Obstinate Cases Research Articles

The applied aspect of socio-psychic causation & trait effect in the context of Swedenberg – Kentian concept of disease development with clinical prospective.

In modern era psychosomatic diseases are very common due to the race of competitive spirit, unsatisfied wants, and covetousness which creates various psychological personalities know as traits i.e. suspiciousness, Conscientious, dictatorial etc. It was the Swedenborg who first developed the concept of being mentally happy, physically healthy and socially benevolent to be mentally and physically healthy and realising the divine aura. Divine aura when descends it first purify soul, the influence of it is then realised in mind and lastly in body. This influx was realised by Dr. Kent. Dr. Kent after being homoeopath, discovered the origin of Hahnemann psora from ‘Mental tension’ and named it ‘Internal itch’ by the base of Swedenborg’s influx principle. Dr. Kent theorised that man is healthy till he is good to his neibour, when he became jealous to others and think ill, the psora enters in the form of “Internal itch”, first pollutes the spirit like vital force which first affects mind and then body. Man shows a deviated pattern of hypersensitiveness or dullness behaviour and physically intolerance to trivial environmental changes or foods. Kent advised to take care of those perverted Mental Generals and Physical generals which are the foundation of disease development. So Dr. Kent advised us to treat Man in disease, not the diseases of man. While investigating disease personality and healthy personality from patient, the Raymond B. Cattell’s personality trait found to be unique fitting best to homoeopathic symptoms and rubrics. 16 personality factors of source trait and abnormal traits are defined with their equivalent rubrics for practitioners. Some obstinate cases are treated with socio-psychic causes rubrics (Internal itch of Kent) gave very remarkable curative results and some cases treated with trait rubrics yield also remarkable curative outcome. Thus it is the study of Swedenborg – Kentian concept for prevention and cure of diseases and the study of Raymond B. Cattell’s source traits and abnormal traits for enlighting Swedenborg - Kentian concept to treat the man in disease, not the diseases of man.

Psora theory of Hahnemann is scientifically immunological sensitization or psycho - pathological somatization or both?: The scientific study with case analysis

Master Hahnemann’s Psora theory has been tested and has undergone the acceptance in obstinate cases where suppression of skin diseases found and has giving remarkable success. The criticism (antithesis) in case of failure in scabies and scabies with superadded fungal or bacterial infection amongst the practicing homoeopaths. Dr. Burnette, Dr. Dugeon did not accepted that scabies can be cured by internal medication of Sulphur alone experienced through their practice. Dr. Clarke opined that ‘all the diseases cannot be categorized into three broad categories only. We need further classification like Burnette’s vaccinosis’. Hebbert A. Roberts called nutritional deficiency and functional disorders as Psora. As Truth is the daughter of time, not of any authority (Lord Bacon), so also psora theory undergoes the scientific processing to verify its validity. In this article, by the help of pathology and psychopathology psora theory is analyzed and interpreted. The pathogenesis of allergic and autoimmune disease giving rise to psoric manifestation is illustrated in figure 1 & 2. The justification of using scabicidal natural or artificial lotion or soap application in scabies along with internal medication as stated by Dr. Dugeon and Dr. Burnette is proven with scientific reasoning. Lastly practical utility of Psora theory for prescription with case studies as per scientific approach is thoroughly elaborated. Prevention of skin diseases by hygiene maintenances and protections from psoric manifestation by simultaneous internal intake of antipsoric medicine as per totality and cleanliness of skin diseases and in case of scabies additional external scabicidal application and/or cleanliness with scabicidal soap are vividly illustrated.

Evaluation of Early Therapeutic Effect of Bone Marrow Mesenchymal Stem Cells Transplantation on Injured Spinal Cord in Albino Rats by Two Routes

Background: Stem cells have created hope for treatment of obstinate cases as injured spinal cord (ISC).Objective: aims to assess possible early therapeutic effect of bone marrow mesenchymal stem cells (BM-MSCs) on regeneration of ISC and to estimate effective transplantation routes in animal models. Material and Methods: 62 adult male albino rats were used; two rats for BM-MSCs extraction and 60 rats were allocated into three groups. Control group: subjected to ISC, intralesional (IL) group: injected with BM-MSCs via intralesional injection and intravenous (IV) group: injected with BM-MSCs via intravenous injection at 3rd day post cord injury (PCI). Rats were examined to assess motor functional recovery. SC specimens were extracted for histological, morphometric, chemical, Immunological and statistical studies. Results: Tracing BM-SCs of SC, (IL) group versus (IV) group showed higher number of engrafted stem cells at all studied ages with gradual decrease from 1st to 6th week PCI. The MSCs counts in (IL) versus (IV) groups were highly significantly increased at 1st, 3rd weeks but only significantly increased at 6th week. They were concentrated at injury site of SC in (IL) group then extended out rostrally and caudally. In (IV) group, they were dispersed over wider area including injury site indicating their capability to home. The mean cavitation areas in treated versus control groups showed highly significant decrease and the smallest cavitation areas observed were in (IL) group. Also (IL) group showed highest neurotrophic factors expressions than other groups with increasing pattern from 1st to 3rd week then decreased at 6th week. Locomotor recovery scores in treated versus control groups showed highly significant increase with highest improvement in (IV) group. Conclusion: This work concluded that early transplantation of BM-MSCs in ISC gave outstanding improvement. Intravenous route therapy provided highest locomotor recovery while intralesional route gave best histological and neuroprotective outcomes.

The problem of obstructive sleep apnea syndrome in asthmatic patients

Asthma and obstructive sleep apnea syndrome (OSAS) are one of the most common chronic respiratory diseases. These have common risk factors that include obesity, gastroesophageal reflux disease (GERD) and impaired nasal breathing (allergic rhinitis, sinusitis). At the same time, experimental evidence demonstrates common pathophysiological mechanisms of these diseases, such as involvement in the process of the respiratory tract, a systemic inflammatory response, and implementation of neuromechanical reflexes. Thus, there is an obvious synergism between these conditions, which affects symptoms, response to therapy, and prognosis. The available data allow discussion on whether there is a need to identify and treat OSAS in asthmatic patients. By keeping in mind the high incidence of OSAS in patients with severe asthma, it may be suggested that treatment for OSAS can reduce the number of exacerbations, improve the quality of life, and decline the number of obstinate asthma cases. It is very important for general practitioners to assess risk factors, such as body weight, nasal stuffiness, and GERD, and to utilize screening tools for more efficient use of healthcare resources. Considering the known positive effects of CPAP therapy in short-term studies, future investigations should focus on the impact of CPAP therapy on asthma symptoms in the long-term, as well as on the effects of asthma drugs on the course of OSAS.

Recalcitrant cervical stenosis unresponsive to traditional attempts at cervical dilatation. successful intrauterine pregnancy following frozen embryo transfer after fluoroscopically guided cervical dilatation and stenting

Recalcitrant cervical stenosis unresponsive to traditional attempts at cervical dilatation. successful intrauterine pregnancy following frozen embryo transfer after fluoroscopically guided cervical dilatation and stenting

Polycystic ovary syndrome: Induction of ovulation

In summarizing the treatment of infertility associated with PCOS, basically the induction of ovulation may be achieved by boosting FSH stimulation of the ovaries, either indirectly with clomiphene or native pulsatile GnRH, or directly with gonadotrophin preparations. There seem to be two main determinants of the success of this treatment in achieving a live birth: the degree of hyperinsulinaemia and the concentration of circulating LH. Either of these, when in excess, not only makes induction of ovulation and conception relatively difficult but is also associated with a high rate of early miscarriage. Their correction, particularly in obstinate cases, should be a major consideration in the attempt to achieve optimal results. With such a range of reasonably successful treatments for the induction of ovulation in PCOS, the emphasis in the selection of therapy should now be placed on minimizing the prevalence of undesired side-effects while retaining acceptable efficiency.

The physiological effects of cellulose in the human large intestine

A diet high in coarse vegetables, fruits and whole grain cereals will generally yield a residue sufficiently bulky to be effective in preventing constipation. But with the modern tendency for the average person to make up a high percentage of his diet of meat, potatoes, white bread, and pastries, constipation has a wide prevalence, and the use of more concentrated roughage materials has been resorted to for the benefit of obstinate cases or for those persons who do not incline toward using a natural roughage diet. With this introduction, Frey et al. (1928) published a study of Dietetic investigations of edible pure cellulose. They described a series of studies where they tested the effects of an edible obtained from the hull of rice grain on gastrointestinal function in human and animal subjects. From the results of their experiments, they recommended their product as a more palatable, yet equally effective, source of roughage than bran, the then accepted supplement to the diet to prevent constipation. Sixty years on, is still considered a potential additive for food products in order to increase their dietary fiber content and for many years the word cellulose was often considered an equivalent term for roughage or fiber. Indeed, it was only in 1982 that Dietary Fiber became a medical heading in Index Medicus; before that time all literature pertaining to fiber was to be found under the heading Cellulose.

DR. JOSEPH CLARKE IN 1797 DESCRIBES HIS TREATMENT OF OBSTINATE COSTIVENESS IN INFANTS

Many well-known physicians of a century or two ago who treated infants and children considered constipation to be a cause of violent convulsions and an incitement to recurrent fever.1 For this reason the treatment of obstinate costiveness in infants was mentioned frequently in the publications of many physicians of the eighteenth and of the first half of the nineteenth centuries. One of the most widely respected of these was Dr. Joseph Clarke (1758-1834), Master of the Rotunda (Maternity) Hospital in Dublin. His enthusiastic recommendation of calomel in the treatment of constipation in infants in one of his papers published in 1797, and quoted here, was widely accepted by practitioners as the drug of choice for this complaint for well over a century. (It wasn't until 1948 that mercury was found in the urine of children with acrodynia.) Every one, acquainted with the constitution of infants, knows that it is natural to them to have three or four stools every twenty-four hours; and that without such discharges they seldom enjoy perfect health. A few instances occur in practice where the intestines of infants never discharge their contents unless irritated by some kind of physic. I have met with a good many such cases, and trying all the ordinary laxative medicines I could not say that any of them was entitled to a preference. The effects of all were temporary only. An ingenious friend and correspondent in London first suggested to me a trial of calomel in such obstinate cases.

The relief of resistant edema by utilization of a sump phenomenon.

Fourteen massively edematous patients with either cardiac disease or nephritis, who had hydrothorax and/or ascites, have proved resistant to the usual diuretic measures, but have been relieved of edema by repeated aspirations of fluid from either the pleural or peritoneal spaces. In the intervals between aspirations the fluid of the interstitial space appeared to seep readily into the sump from which fluid had just been removed. The repeated aspirations did not result in hyponatremia nor hypoproteinemia in these cases. As a means of by-passing "`reluctant" kidneys the utilization of the sump phenomenon has proved simple, safe and effective in some very obstinate cases.

Tuberculosis meningitis and its management.

1. An analysis of thirtyone cases of tuberculous meningitis has been presented. 2. It has been shown that the disease is on the increase. 3. Early diagnosis (clinical and C.S.F. changes) and intensive treatment for a prolonged period is necessary for cure. 4. Prognosis has been revolutionised by the new chemotherapeutic and antibiotic group of drugs. 5. Treatment of choice (specific therapy) at the present time is (a) streptomycin and hydrazide intramuscularly, (b) streptomycin intrathecally and hydrazide intrathecally in obstinate cases, (c) PAS orally.

RADIATION THERAPY FOR CONDUCTIVE DEAFNESS: Report of Results and Discussion of Roentgen and Radium Irradiation

THE WORK of Crowe and associates at the John Hopkins University has initiated and popularized radium irradiation of the nasopharynx for a certain type of deafness. That radium was successfully used for aerotitis in the recent war is well known from the numerous enthusiastic reports of the air and submarine forces. Bordley1stated that irradiation of the nasopharynx resulted in appreciable useful increase in hearing acuity in 45 per cent of the children selected for treatment of conductive deafness. He further stated that only 25 per cent of selected adults showed such improvement. Full page advertisements of the radium applicator in the special journals urge its use in such allied conditions as recurring attacks of acute otitis media, obstinate cases of chronic otitis media and certain types of cough and asthma. This is a large order. MODE OF ACTION The therapeutic action of the monel metal radium applicator is

Primary constipation: Treatment

The foregoing is an overall program which will produce satisfactory results in the most obstinate cases of Primary Constipation. In mild cases, good results are frequently obtained when the patient is instructed to take only the water and vegetables, or it may be necessary to add the salt or even the mineral oil. In extreme cases, in order to gain the confidence of his patient, the physician may outline the entire anticonstipation program in the beginning, and when he finds the patient having too many movements, he can cut down first on the oil, then on the salt, and later on fluid or diet, but one at a time, until only one defecation daily is achieved. Very frequently, in long-standing and obstinate cases, the defecation reflex has been so increased (19) that the individual is not aware that a bowel movement is imminent until great pressure is exerted. Therefore, when the regimen is first started, he should be told to be on the alert for vague symptoms of fullness in the rectum. He may wonder if he should try to have a movement. In case this occurs, and it frequently does soon after the water has been taken, he should at least go to the toilet to see what will happen. No straining is needed. If he delays, the effect of the water may be lost, and movement will not take place until later in the day, or not at all. As his habit becomes established, the threshold of the defecation reflex is lowered, and an unmistakable urge will be present. The busy family physician mav feel that this program is too involved. We do not find it so, although, it is sometimes necessary to question the patient at length in order to find in just what respect instructions arenot beine: followed. Many persons, who have taken laxatives and enemas all their lives, seem to take a fiendish delight in proving their doctor wrong, but we have found that a little persistence and patience give brilliant results in a high percentage of cases. During the past five years, prescriptions for laxatives have been almost eliminated in this clinic and in our private practice.

Modification of the munro tidal drainage apparatus

W HEN Munro first presented his conception of tida1 drainage of the urinary bIadder in 1934, it apparentIy was not evident to the uroIogists discussing the paper that this method of treatment had uroIogic significance. However, it was soon discovered that this was a valuabIe and dependable addition to their therapeutic armamentarium, and modifications of the origina apparatus for specia1 cases were devised. We wish to present two such modifications: the first having very genera1 application and the second a very Iimited one. Tidal drainage was first utiIized by the uroIogist for the treatment of cystitis, particularly in those obstinate cases which did not respond to recognized measures. The value of the treatment Iies in the regular, automatic distention and irrigation of the bladder. With the origina apparatus, the reservoir and tubing had to be fiIIed at each cycIe before any fluid entered the bIadder, and the evacuation of the viscus was sometimes incompIete. It was evident that with constant irrigation the modaIity wouId be more effective. For this purpose, the modification shown in Figure I was devised. EssentiaIIy, it consists of a twoway catheter with tidal drainage apparatus attached to the outflow. AI1 the ffuid entering the apparatus must first pass through the bIadder. ActuaI tests have shown that a soIution of indigo carmine wiI1 be cIeared from the bladder in haIf the time that is required with ordinary tida1 drainage. This modification is vaIuabIe in the treatment of a11 types of cystitis, but particuIarIy so when the urine is markedly infected or when incrustations are present, and perDENVER, COLORADO

Treatment of trichomonas vaginalis

TEUCORRHEA is one of the commonL est complaints among gynecoIogica1 and obstetrica patients. From the symptomatic standpoiht, it is usuaIIy the first to arise and the Iast to disappear. Davis,l in examining IOOO femaIe patients, found that 33 per cent had some type of discharge. This is about the percentage in my practice and in the gynecoIogica1 cIinic of the Jefferson Davis HospitaI, Houston, Texas. Trichomonas vaginaIis is one of the most common causes of Ieucorrhea, but had been overIooked unti1 our research at the University of Texas SchooI of Medicine. The first case of trichomonas vaginaIis reported in the United States was by George Dock2 in GaIveston, Texas, where most of this research was carried out. The first papers on trichomonas vaginaIis were reported by Donne3 in 1837 and Iater ones by KunstIer4 in 1893 and 1894, by Benson in Igr 2, DeLee5 in 1920, ReuIing6 in 1 g2 I, Hegner7 in 1925, BIand and RakofP in 1932. Since that time many American authors, such as HesseItine,g Drabkin,lO Buxton and SheIanski,ll and the author12 have added to the Iiterature. Incidence of Trichomonas Vaginalis. In 1932 at the John SeaIy HospitaI, GaIveston, 500 consecutive women coming to the outpatient cIinics of the hospita1 were examined. There were 187 positive cases of trichomonas vaginaIis, a percentage of 37.4. There were 300 negro and 200 white femaIes; 46.3 per cent of the negro femaIes, and 24.0 per cent of the white femaIes harbored the organism. These patients ranged from I I to 52 years of age. The Iargest percentage of positive cases of trichomonas vaginaIis Iay between the ages of Ig and 33 years with the Iargest singIe group at 23. According to the author’s statistics, based upon the examination of over 10,000 women, trichomoniasis was present in 37.5 per cent of the gynecoIogica1 and obstetrica patients in GaIveston, Texas, a seaport, and in onIy 27 per cent of the same class of patients in Houston, Texas, 52 miIes inIand. The author has examined more than 25,000 femaIe patients for trichomonas vaginaIis during the past eight years and the percentage of patients found positive was 25.5 per cent. Urinary Infections. FIashkamp14 found trichomonas vaginaIis in the urine in one out of 250 patients examined, and Saye+ in 27 per cent of 2 12 patients examined. Sayer beIieves the bIadder to be the norma habitat for trichomonas vaginaIis. In our resistant and obstinate cases, we find trichomonas vaginaIis more often in the bIadder. Whenever one fails to cure trichomonas vaginaIis by the routine method, such as fforaquin and vinegar douches, then at the same time as the vagina is treated, the bIadder is irrigated with boric acid foIIowed by the instiIIation of argyro1. Signs and Symptoms. The patient usuaIIy compIains of a discharge or “whites” with an itching and burning, or chafing, of the externa1 genitalia and inner aspect of the thighs. No other discharge produced by the vagina1 mucosa and no other microorganisms besides the trichomonas vaginaIis causes a scaIding sensation of the vagina, vuIva and perineum. The discharge is usuaIIy thin and creamy in coIor, but it may be thick and yeIIowish. At times it is diffIcuIt to distinguish trichomonas infection from gonorrhea1 infection. The discharge of trichomonas vaginalis usuaIIy resists a11 types of treatment, but it may sometimes be checked by

Certain postoperative complications of cataract operations: With especial reference to a study of 1,004 operations

Certain postoperative complications of cataract operations: With especial reference to a study of 1,004 operations

Surgical treatment of ovarian dysfunctions

I have presented five cases of ovarian hypofunction, with ovarian pain, all of whom were benefited by excision of one or both ovarian cortices. Another case, of hyperfunction with pain has apparently been relieved functionally and subjectively by excision of part of each ovary, combined with almost complete decortization.Surgical treatment of ovarian dysfunction should have a very limited field of usefulness, but it is my opinion that there is a place for it if we are to utilize all the facilities at our command. Many of these patients become actually psychic, due to almost constant pain, and with their inordinate fear of the consequences of abnormal sex functions.Partial decortization alone appears to be beneficial in relieving ovarian hypofunction, and pain.Excision of a segment of ovarian parenchyma, usually without decortization, may be beneficial in some obstinate cases, in dealing with hyperfunction.A combination of the procedures might be undertaken if ovarian pain accompanies hyperfunction.I realize that the cases presented are not complete from the standpoint of an endocrinologist, and his criticism might be that they were not adequately treated from a medical standpoint. Furthermore the number of cases is too small to warrant definite conclusions. However, I present them for your discussion and judgment.

A COMPARATIVE STUDY OF CLINICAL BISMUTH TREATMENTS

The extensive use of bismuth as a spirocheticide in the treatment of syphilis is comparatively recent. It has been recommended in particular for obstinate cases, wherein it is regarded by some as probably superior to mercury. According to expert students¹of the subject, the clinical efficiency of treatment with bismuth compounds in syphilis has been sufficiently demonstrated by all the available methods—by clinical progress, by the disappearance of spirochetes from lesions, and by the reversal of the Wassermann reaction. Many compounds and preparations of bismuth have been employed, so that the question of choice has come to the forefront. This is particularly true because the soluble preparations involve the danger of absorption of poisonous amounts of bismuth. According to Sollmann, Cole and Henderson¹it may be presumed that compounds which differ in solubility differ also in rapidity of absorption, and therefore of excretion, and in promptness and duration

Some observations on the value of intratracheal injections of iodized oil for bronchial asthma

A BOUT seven years ago, while using iodized oil for diagnostic purposes, my attention was directed to the improvement that often followed t,he injection of iodized oil into the lungs of certain patients with bronchial asthma. This was a suggestion that seemed to be worth further consideration, and I began a study of the problem in order to determine whether the intratracheal injection of iodized oil was of any value in the treatment of this disorder. These observations are based on a study of 60 cases drawn from private practice and from the wards and dispensary of the Western Pennsylvania Hospital, Pittsburgh. They were unselected as to etiologic factors, duration of the condition, or age, with the one exception that children under twelve years of age, owing to the technical difficulties of injecting the oil, were excluded until positive evidence of the value of this method of treatment was fully established. Most of the patients were of the chronic type and had received the various treatments for this condition without results. There is only one patient in the group in whom the duration of asthma was less than four years. In all others the condition had existed from four to forty-eight years. In many of the cases the asthma had existed from infancy or early childhood. About half the number of this group were susceptible to foreign proteins ; in the other half, the excitant was peripheral, psychic, or due to infection of the respiratory system. Influenza too,k the lead among the various infections of the respiratory system. In many of the patients this condition was accompanied by chronic bronchitis, hay fever, emphysema, or myocardial changes of years’ duration. Dyspnea due to the emphysema was as distressing to the patient as were the ast,hmatic paroxysms. Response to the treatment with iodized oil varied widely, and in certain obstinate cases a changed chemical composition has seemed indicated, and has been attended with improved results clinically. In certain types of cases the response has been prompt ; but in others, tardy, months being required to bring relief of definite character. That the administ,ration of the oil should be cautious is indicated by the fact t,hat in some cases the first injection precipitated an immediate attack, which, however, was usually followed by definite improvement. In the others, the attacks decreased in frequency and severity after the

PERSISTENT VAGINAL DISCHARGE IN INFANTS AND IN LITTLE GIRLS

The usual treatment for acute vulvovaginitis in infants and in little girls has seemed fairly satisfactory, because, with ordinary measures insuring cleanliness and mild antisepsis, the condition is apt to be self-limited. The treatment for chronic vaginitis or vulvovaginitis, especially with a complicating endocervicitis, offers a much more difficult problem. I will present some material which has been of great assistance in the study and treatment of these obstinate cases in private and in institutional practice. The common complaint is of a vaginal discharge of long duration which is noticed because the clothing is stained, or because there is irritation about the vulva. Burning urination or the presence of an odor may be the complaint. Occasionally there is a history of atypical acute vulvovaginitis, preceding the chronic condition, but it is uncommon to obtain a history of real value in regard to the possible source of infection. The picture is

The inhibition of putrefactive spore-bearing anaerobes by bacterium acidophilus

There is available, however, no definite information in regard to the biologic or chemical factors which permit these aciduric organisms to become predominant. The investigations of Kendall,2 Torrey,3 Rettger and his co-workers 4 and others have established the fact that diets containing liberal amounts of lactose are particularly effective in stimulating the overgrowth of B. acidophilus in the intestine, and one of us 3 has also recently demonstrated that dextrin is equally efficacious. Further, through the studies of Hull and Rettger4 and Rettger and Cheplin,5 it has been shown that lactose and dextrin are so slowly absorbed from the digestive tract that a part of the amount fed reaches the lower bowel, the normal habitat of these bacilli. This, as Rettger has emphasized, provides a favorable pabulum for B. acidophilus and permits the rapid development of this organism. It would seem, however, that these conditions might be equally favorable for the growth of such fermentative organisms as B. coli and streptococci and that the predominance of B. acidophilus is probably attained through factors other than or additional to more mechanical overgrowth. Kopeloff7 in an inquiry into the cause for the improvement in obstinate cases of constipation following the ingestion of large amounts of B. acidophilus milk cultures with a consequent simplification of the intestinal flora,