Observer Performance Tests Research Articles

50μm両面集光CR-mammography : 画質特性と検出能におけるX線斜入射の影響

In mammography units, the X-ray tube focal spot is located directly above the chest wall edge of the detector. Therefore, the X-ray beam is incident at a different angle along the cathode-anode axis. When the X-ray beam is incident on the imaging plate (IP) at a relatively large angle, the resolution property of a new imaging plate with dual-sided reading system would be degraded compared with the conventional imaging plate because of the parallax effect, which produces a shift in the image on two sides of the imaging plate. To evaluate the oblique incidence effect of the X-ray beam on the degradation of resolution properties and detection of simulated microcalcifications of a new CR system with a pixel size of 50 microm, its basic imaging properties and observer performance tests were compared with those of a conventional CR system. The resolution properties were evaluated by measuring modulation transfer functions (MTFs). Observer performance tests were conducted to compare the detectability of simulated microcalcifications of CR systems. Degradation of presampling MTFs for the new system is greater than that of the conventional CR system when the X-ray beam was incident at the same angle on the imaging plate. We found that the degradation of the area under the ROC curve (Az) for the new CR system was greater than that of the conventional CR system when the X-ray beam was incident at the same angle on the imaging plate.

Physical Imaging Properties and Low-contrast Performance of a Newly Developed Flat-panel Digital Radiographic System

We investigated the clinical usefulness of a newly developed flat-panel detector (FPD) system by comparing its physical imaging properties and low-contrast detectability with those of a current FPD system. The newly developed CsI-based indirect FPD (Canon, CXDI-40C) and current Gd(2)O(2)S-based FPD (Canon CXDI-11) systems were used. Characteristic curves, resolution properties, radiographic noise, detective quantum efficiencies (DQEs) and low-contrast detectability for both systems were measured. The new FPD system showed considerably lower noise levels than those of the current FPD system. DQE (0) s of the new and current FPD systems were 75% and 35%, respectively. Observer performance tests of the contrast-detail (C-D) phantom indicated that the new FPD system can significantly improve low-contrast performance over that obtainable with the current FPD system under the same conditions of exposure. The new FPD system provided approximately 50% reduction in exposure while providing comparable detectability. The newly developed FPD system provides radiographic images with excellent inherent physical image quality and low-contrast performance.

Full-field digital mammography with amorphous silicon-based flat- panel detector: physical imaging characteristics and signal detection

The physical characteristics of a clinical amorphous silicon-based flat-panel imager for full-field digital mammography were investigated. Pre-sampled modulation transfer functions (MTF) were measured by using a slit method. Noise power spectra were determined for different input exposures by fast Fourier transform. The MTFs of full-field digital mammography systems showed significantly higher values than those of the computed radiography (CR) system. The full-field digital mammography system showed a lower noise level than that of the CR system under the same exposure conditions. Contrast detail analysis has been performed to compare the detectability of the full-field digital mammography system with that of the screen-film (Min-R 2000/Min-R 2000) system. The average contrast-detail curves of digital and film images were obtained from the results of observation. Image quality figures (IQF) were also calculated from the individual observer performance tests. The results indicated that the digital contrast-detail curves and IQF, on average, are superior to those of the screen-film system.

Computer‐aided diagnosis for detection of changes in sequential chest radiographs (in Japanese)

The subtraction image of digital chest radiographs taken at different times improved the diagnostic accuracy of radiologists viewing screening chest radiographs. The accurate registration of two chest images using “lung markings” instead of “rib edges” enables us to detect subtle changes in the “difference image.” The “lung markings” are the shadows of blood vessels traversing lung substance. Most of the morbid changes grow in lung substance not in the rib cage. Twenty‐nine pairs of posteroanterior chest radiographs with and without temporal morbid changes were selected from approximately 200 sequential cases. The images were 1760×1760 matrix and 1024 gray scale with a computed radiography system (Fuji Medical System, Tokyo). Image registration employed the matching of “lung markings” in the two radiographs. Observer performance tests with and without the use of the “difference image” were carried out by eight radiologists. Six of the eight observers diagnosed with higher sensitivity. The mean for eight observers increased from 43.9% to 55.3% with a statistical significance of The mean area under the AFROC (Alternative Free‐Response Receiver Operating Characteristics) curve improved from 0.596 to 0.647 with a statistical significance of The false positive response was comparable with and without the use of the subtraction image. We conclude that the use of the subtraction image with the new registration technique improves the diagnostic accuracy for detection of subtle changes between radiographs, such as nodule, infiltrate, and cardiomegaly of radiographic findings.

A perceptually tempered display for digital mammograms.

The cathode ray tube of a workstation for use with digital mammograms was calibrated with a photometer to produce an input-output characteristic curve similar to the perceptually linear curve defined by a current display standard. Then, a test pattern consisting of bars of increasing intensity containing disks of decreasing contrast was used by an observer to estimate the minimal detectable contrast (MDC) at different levels of display luminance. The MDC was modeled by a parabola. The shape of the parabola was determined by the observer's perceptual responses, and the range was determined by the maximum and minimum pixel values of the breast parenchyma. As each mammogram was displayed, the contour of the breast was automatically found and pixels within the breast image were sampled to determine the pixel values that were used to compute the maximum and minimum pixel values. The parabola was integrated to determine the look-up table for the initial MDC-tempered display of the mammogram. Preliminary observer performance tests showed no significant differences in the accuracy and speed of three radiologists who read a set of mammograms when the MDC-tempered display was compared with the perceptually linear display.

Assessment of image quality in dental radiography, part 2: Optimum exposure conditions for detection of small mass changes in 6 intraoral radio-graphy systems

Objective. The purpose of this study was to compare 2 film systems and several digital intraoral systems with regard to visual image quality through use of a test phantom developed for this purpose. Study Design. The detectors used for digital imaging were as follows: Computed Dental Radiography (CDR), Digora, Dixel, and Sens-A-Ray without scintillator layer. Two types of digital images were prepared for the observer performance test: one with original gray scales and another with contrast enhancement. Images with and without enhancement from the 4 systems were displayed to 7 observers. The change in the average number of perceptible holes was plotted against exposure, and modified perceptibility curves were created and compared with curves for the film systems. The exposure level at which the maximum number of holes was perceived was defined to be optimum. The optimum exposure levels were determined for each digital system and compared with that of the film systems. At the optimum exposure, the average maximum numbers of perceptible holes in each digital system with and without contrast enhancement were compared with the maximum numbers for the film systems. The minimum exposure levels were determined to be those at which the number of perceptible holes exceeded the number for film, and the possibility of exposure reduction was evaluated. Results. All digital systems except the Digora system showed lower optimum exposures than E-speed film. In all digital images without enhancement, however, the maximum number of perceptible holes was significantly lower than that for the film systems at that exposure. With contrast enhancement, all digital systems except the Sens-A-Ray system showed visibility superior to that of the film systems. With the CDR, Digora, and Dixel systems, exposures could be further reduced by a considerable amount, with greater retention of information than was associated with film. Conclusions. Our results strongly suggest that digital systems, if properly used, can exceed film systems in the detection of small mass changes. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;87:123-9)

The Scientific Work-Up of Radiographic Image Quality Now and a Decade Ago: The Radiologist's Approach

The past decade has seen a number of efforts to increase image quality and decrease examination hazards to the patient in medical imaging. A comparison of image quality studies in the early 1980s with those of the early 1990s shows that the amount of scientific publications on the topic as well as their sophistication has grown. The concept of diagnostically relevant structures as well as the observer performance test with receiver operator characteristics analysis has been well received. On the basis of our own experience in projection radiography a three-step approach to the evaluation or optimisation of new imaging modalities is proposed: (1) base evaluation applying adequate physical parameters; (2) subjective optimisation of the system with the diagnostic objectives in mind (i.e. the diagnostically relevant structures in radiographic studies) to generate a set of alternative hypotheses; and (3) comparison of these hypotheses with clinically oriented observed performance tests.

The Effect of Irreversible Image Compression on Diagnostic Accuracy in Thoracic Imaging

Digital image compression reduces the storage requirements and network traffic on picture archiving and communications systems. Full-frame bit-allocation (FFBA) is an irreversible image-compression method based on the discrete cosine transform that provides for high compression ratios with a high degree of image fidelity. One hundred twenty-two posteroanterior chest radiographs were obtained on patients in an ambulatory patient setting, including 30 cases of interstitial lung disease, 45 images containing combinations of lung nodules (N = 37) or mediastinal masses (N = 39), and 47 normal images containing none of the pathology for which we were testing. The images were digitized (nominal 2 K x 2 K x 12-bit resolution), printed on a 35 x 35-cm hard copy format, and compressed at an approximate compression ratio of 20:1. Observer performance tests were conducted with five radiologists using receiver operating characteristics analysis on digitized uncompressed and compressed hard copy images. There were no significant differences between the two display conditions for the detectability of any of the thoracic abnormalities. Our preliminary results suggest that irreversible image compression at ratios of 20:1 may be acceptable for use in digital thoracic imaging.

Quantitative assessment of digitized portal images: effect of sampling frequency on observer performance.

To investigate spatial resolution requirements for digitized portal images in radiation therapy, observer performance tests were performed. One hundred twenty portal images were digitized with sampling frequencies of 0.700, 0.350, and 0.175 mm for observation. Receiver operating characteristic analysis was used to determine the acceptable sampling frequency for clinical portal images. The detectability of setup errors was significantly better on the original images than on the digitized images with sampling frequencies of 0.700 mm (P = .005) and 0.350 (P = .046). Some clinical disadvantages might accrue with the use of a sampling frequency of 0.350 mm or larger.

A Fully Automated Adaptive Unsharp Masking Technique in Digital Chest Radiograph

The authors are developing a fully automated adaptive unsharp masking technique with parameters that depend on regional image features of a digital chest radiograph. A chest radiograph includes various regions such as lung fields, retrocardiac area, and spine. These areas have very different texture patterns and optical densities. Therefore, for best evaluation, it is necessary to enhance the image contrast of each region by an optimal parameter. In the current study, a chest radiograph was automatically divided into three segments (lung field, retrocardiac area, and spine) by using a histogram analysis of pixel values. The lung fields and retrocardiac area were selectively enhanced with a small mask size and mild weighting factors that had been previously determined to be optimal. The spine was enhanced with a large mask size and adequate weighting factors. An observer performance test indicated that this technique provides excellent diagnostic accuracy for simulated nodules in chest radiographs.

Direct comparison of conventional and computed radiography with a dual-image recording technique.

To compare the image quality of computed radiographic (CR) with conventional screen-film images, the authors used a dual-image recording technique. Images were simultaneously acquired with a conventional screen-film combination and a storage-phosphor imaging plate loaded into a single cassette. Wiener spectra and modulation transfer function were compared for both image types. A preliminary observer performance test was conducted with chest images obtained with the dual-image recording technique on portable and fixed equipment. Analysis of physical parameters and observer test results suggests that the conventional screen-film system can provide slightly superior image quality, although the CR system has some advantage in bedside applications.

5. ROC 解析(ディジタルラジオグラフィの画像評価)

The image quality in a computed radiography system (CR) was evaluated with observer performance tests using receiver operating characteristic (ROC) analysis. The detectability of low-contrast object (2mmφ beads) was compared CR with screen-film system. Effects of incident exposure to the imaging plate (IP) and image processing (contrast enhancement, unsharp masking) on the detectability of low-contrast object were also studied. The results indicated that the detectability of low-contrast object in a CR system was comparable to that of the medium-speed screen-film system. However, the detectability of low-contrast object in a CR system depended on IP size and decreased with incident exposure decreasing and increased by using contrast enhancement or unsharp masking.

Digital chest radiography: effect on diagnostic accuracy of hard copy, conventional video, and reversed gray scale video display formats.

Observer performance tests were conducted to compare the effects on diagnostic accuracy of hard copy (film) versus video display and to determine the diagnostic merits of conventional negative ("white bone") versus positive ("black bone") video displays. Subjective preferences were elicited from each observer for each display modality, and diagnostic accuracy was determined with receiver operating characteristic analysis. Digitized chest radiographs were used, including normal and abnormal cases with a variety of subtle abnormalities. The hard copy was printed with a 1,024 X 1,024-matrix by a high-quality drum scanner in conventional white bone format only. The video images were displayed on a 1,023-line monitor (30 Hz, interlaced) in both white bone and black bone formats with fixed window and brightness settings. Most observers preferred hard copy to video, but preferences were sharply divided between white bone and black bone video. Diagnostic accuracy was significantly greater with hard copy than with video display, and the conventional white bone format was significantly superior in accuracy to the black bone display.

Digital radiography of subtle pulmonary abnormalities: an ROC study of the effect of pixel size on observer performance.

Forty conventional radiographs with examples of mild interstitial infiltrates and subtle pneumothoraces and 40 normal studies of the chest were selected and digitized, with pixel sizes of 1.0, 0.5, 0.2, and 0.1 mm. Observer performance tests were carried out using receiver operating characteristic analysis. Conventional radiographs and digitized images were compared. The results indicate that, in such cases, diagnostic accuracy increases significantly as the pixel size is reduced, at least to the 0.1-mm level. We conclude that, for digital systems using screen-film or similar image receptors, use of a pixel size substantially larger than 0.1 mm may result in some loss of diagnostic accuracy.

Digital projection radiography of the chest.

Direct and film-based radiographic systems are undergoing evaluation by observer performance studies for use in digital imaging of the chest. Many issues intrinsic to digital imaging are not settled, including the minimal pixel size necessary for images of accurate diagnostic quality, the characteristics of the display console, and the usefulness of digital imaging processing techniques. The chest is a particularly difficult anatomic region for examination by digital radiography because of the broad spectrum of disease findings encountered. These issues are discussed in reference to four reports that use observer performance tests for evaluating various facets of chest diagnosis using digital radiography.

Anticrossover emulsions evaluated by observer performance tests.

Observer performance in the detection of pulmonary nodules and infiltrates was measured using film coated with anticrossover emulsion, a recent innovation in radiographic film that is expected to produce sharper images because of improved resolution. Test radiographs of an anthropomorphic phantom were shown to six experienced observers. Radiographs containing pseudonodule and pseudoinfiltrate images were obtained with the anticrossover film and the same type of film without the anticrossover coating. Test images contained single nodules, single infiltrates, or both; approximately 45% of the test radiographs were normal. Individual receiver operating characteristic (ROC) curves were formed, and sensitivity and specificity values were calculated. The results demonstrated an improvement in observer performance with the anticrossover film as measured by sensitivity and the area under the average ROC curves.