In Large-Eddy Simulation (LES), the turbulence inflow can be generated synthetically, where the input value of the maximum turbulence frequency can impact the accuracy. LES efficacy can be influenced by the designated computational domain (CD) size and grid specifications. This study proposes multiple parametric studies that aim to correlate the effective parameters controlling the accuracy of numerical wind load evaluation on a low-rise building without compromising the computational cost. The study includes the efficient selection of turbulence maximum frequency (fmax) that can accurately capture the pressure fluctuation induced on the building facade. Both CD size, which involves the distances from the building to the boundary condition, and CD discretization in terms of grid size scheme and shape, are examined. The error assessment is conducted by comparing wind flow aerodynamics and evaluating the RMSE for the pressure parameters with respect to the wind tunnel test. The findings of this study suggest using fmax which can be resolved by the minimum grid size as an input in the inflow turbulence generated to accurately transport the majority of eddies when a satisfactory wavelength of 4 Δx is utilized. This study shows that computational domain size and discretization can be significant sources of error that can reach 21 %, compromising the reliability of computational wind load predictions. The current code in selecting computational minimum width and length is found to be insufficient. In addition, it is found that there are currently no recommendations for selecting the width computational dimension specifications when examining low-rise buildings oriented in an oblique wind direction. The domain grid specification induced a considerable error of 14 % in the mean pressure across the roof when tetrahedral grid shapes were used. Overall, this study's proposed recommendations can significantly impact the efficacy of computational wind load evaluation for low-rise building geometry.