Sequential Monte Carlo (SMC) represents a principal statistical method for tracking objects in video sequences by on-line estimation of the state of a non-linear dynamic system. The performance of individual stages of the SMC algorithm is usually data-dependent, making the prediction of the performance of a real-time capable system difficult and often leading to grossly overestimated and inefficient system designs. Also, the considerable computational complexity is a major obstacle when implementing SMC methods on purely CPU-based resource constrained embedded systems. In contrast, heterogeneous multi-cores present a more suitable implementation platform. We use hybrid CPU/FPGA systems, as they can efficiently execute both the control-centric sequential as well as the data-parallel parts of an SMC application. However, even with hybrid CPU/FPGA platforms, determining the optimal HW/SW partitioning is challenging in general, and even impossible with a design time approach. Thus, we need self-adaptive architectures and system software layers that are able to react autonomously to varying workloads and changing input data while preserving real-time constraints and area efficiency. In this article, we present a video tracking application modeled on top of a framework for implementing SMC methods on CPU/FPGA-based systems such as modern platform FPGAs. Based on a multithreaded programming model, our framework allows for an easy design space exploration with respect to the HW/SW partitioning. Additionally, the application can adaptively switch between several partitionings during run-time to react to changing input data and performance requirements. Our system utilizes two variants of a add/remove self-adaptation technique for task partitioning inside this framework that achieve soft real-time behavior while trying to minimize the number of active cores. To evaluate its performance and area requirements, we demonstrate the application and the framework on a real-life video tracking case study and show that partial reconfiguration can be effectively and transparently used for realizing adaptive real-time HW/SW systems.