Objective Grading System Research Articles

Comprehensive Grading System for Experimental Autoimmune Uveitis in Mice.

Experimental autoimmune uveitis (EAU) is the most commonly used animal model to study the progression of chronic uveitis and to test various therapies to treat the disease. However, to accurately evaluate the effectiveness of such treatments, a grading system that combines the latest imaging techniques with definitive quantitative grading thresholds is required. This study aimed to develop a comprehensive grading system that objectively evaluates EAU progression in C57BL/6J mice. EAU was induced following immunisation with interphotoreceptor retinoid-binding protein (IRBP) and pertussis toxin. Weekly fundus and optical coherence tomography (OCT) images were acquired over 12 weeks using a Micron IV imaging system. Each mouse was graded (between 0 to 4) based on changes seen on both the fundus (optic disc, retinal blood vessels and retinal tissue) and OCT (vitreous and retinal layers) images. A total EAU response (with a maximum score of 48) was calculated for each mouse based on the sum of the individual scores each week. Analysis of the clinical scores depicted a gradual increase in inflammatory signs including optic disc and vascular swelling, leukocyte infiltration in the vitreous, lesions in the retina and formation of granulomas and hyper-reflective foci in the retinal layers in EAU mice, with most signs reaching a plateau towards the end of the study period. Development of these signs into sight-threatening complications such as optic disc atrophy, structural damage to the retina and subretinal oedema were noted in 80-90% of mice suggesting consistent disease induction. Overall, a comprehensive and objective grading system encompassing all pathologies occurring in EAU mice was developed to enhance the preclinical evaluation of novel uveitis treatments.

Predicting the likelihood of live birth: an objective and user-friendly blastocyst grading system

Research questionCan day-5 blastocysts be ranked according to their likelihood of live birth using an objective and user-friendly grading system? DesignA retrospective multicentre study conducted between 2017 and 2019, including 1044 day-5 blastocysts. Blastocyst expansion degree, trophectoderm and inner cell mass quality were assessed morphologically and morphometrically. Several analyses were conducted: the association between the qualitative and quantitative assessment for the blastocyst expansion degree and the number of trophectoderm cells; the effect of the embryo quality on day 3 and the contribution of the three blastocyst parameters to live birth, with logistic regression; and a decision tree with the most significant variables to create the new scoring system. ResultsCut-off points were found to discriminate between expanding and expanded blastocysts (165 µm for blastocyst diameter) and between trophectoderm grades (A: ≥14 cells; B: 11–13 cells; C: ≤10 cells). When the embryos reached the blastocyst stage, their quality on day 3 did not add predictive value for implantation and live birth. In the logistic regression analysis, the only parameter capable of significantly predicting the live birth likelihood was the trophectoderm grade: A versus C (OR 1.95, 95% CI 1.26 to 3.0); B versus C (OR 1.71, 95% CI 1.22 to 2.4). The decision tree supported the finding that the trophectoderm grade had the highest predictive value for a live birth, followed by the blastocyst expansion degree in a second step. ConclusionsThis new method makes objective blastocyst assessment feasible, allowing for standardization and exportation to other laboratories worldwide.

Computerized dynamic occlusal analysis and its correlation with static characters in post-orthodontic patients using the T-Scan system and the ABO objective grading system

ObjectivesThis study was conducted to detect the overall performance of both static and dynamic occlusion in post-orthodontic patients using quantified methods, and to ascertain the correlation between the two states of occlusion.Materials and methodsA total of 112 consecutive patients evaluated by ABO-OGS were included in this study. Based on the pre-treatment Angle’s classification of the malocclusion, samples were divided into four groups. After removing orthodontic appliances, each patients underwent the American Board of Orthodontic objective grading system (ABO-OGS) and T-Scan evaluations. All the scores were compared within these groups. Statistical evaluation included reliability tests, multivariate ANOVA, and correlation analyses (p < 0.05 was considered significant).ResultsThe mean ABO-OGS score was satisfactory and did not differ by Angle classifications. The indices making substantial contributions to ABO-OGS were occlusal contacts, occlusal relationships, overjet, and alignment. Disocclusion time in post-orthodontic patients was longer than normal. Occlusion time, disocclusion time, and force distribution during dynamic motions were considerably influenced by static ABO-OGS measurements, especially occlusal contacts, buccolingual inclination, and alignment.ConclusionPost-orthodontic cases that passed the static evaluation of clinicians and ABO-OGS may nevertheless be left with dental casts interference in dynamic motions. Both static and dynamic occlusion should be extensively evaluated before ending orthodontic treatment. Further research is needed on dynamic occlusal guidelines and standards.

Treatment Effectiveness of Clear Aligners in Correcting Complicated and Severe Malocclusion Cases Compared to Fixed Orthodontic Appliances: A Systematic Review.

This systematic review aimed to critically assess the available evidence regarding the effectiveness and efficiency of clear aligners in the comprehensive treatment of complex cases accompanied by premolars extraction. An electronic literature search by two reviewers was independently done on 27 February 2023 in the following databases without time and language limitations: Pubmed®, Scoups®, Google Scholar, Cochrane Library database, Web of Science™, and Proquest Database Open. Randomized controlled trials (RCTs) of any type, non-randomized clinical trials (CCT), cohort studies, and prospective, retrospective, and cross-sectional studies were reviewed. The risk of bias in included studies was assessed using the Risk of Bias (RoB 2.0) tool for randomized trials and the Risk of Bias in Non-randomized Studies (ROBINS-I) tool for non-randomized studies. After carefully searching the literature, six trials were included in this systematic review, three RCTs, two retrospective cohort studies, and one CCT. Two hundred eighty-three patients were included (186 females, 97 males). Three studies found that there were no differences between the clear aligners and fixed appliances when evaluations were done using the American Board of Orthodontists Objective Grading System (ABO-OGS) or the Peer Assessment Rating (PAR) index. Two studies found that there were some differences between predicted and achieved tooth movements when clear aligners were used in premolars extraction cases. Based on the included studies, the duration of treatment was shorter with fixed appliances than the clear aligners when applied to orthodontic extraction cases. Both clear aligners and fixed appliances were found effective in the orthodontic treatment of premolar extraction-based cases. Fixed appliances have the advantage of achieving better buccolingual inclination and occlusal contacts in a shorter treatment duration. Treatment with clear aligners might be associated with differences between predicted and achieved tooth movements. Therefore, the characteristics of these techniques should be considered when making a treatment decision.

Objective and automatic grading system of facial signs from smartphones' pictures in South African men: Validation versus dermatologists and characterization of changes with age.

To evaluate the capacity of the automatic detection system to accurately grade, from selfie pictures, the severity of eight facial signs in South African men. Selfie pictures (obtained from frontal and back cameras) of 281 South African men differently aged (20-70years) were obtained and analyzed by an automatic artificial intelligence (AI)-based automatic grading system. Data were compared with the clinical gradings made by experts and dermatologists. In all facial signs, both series of gradings were found highly correlated with, however, different coefficients (0.59-0.95), those of marionette lines and cheek pores being of lower values. No differences were observed between data obtained by frontal and back cameras. With age, in most cases, gradings show up to the 50-59year age-class, linear-like changes. When compared to men of other ancestries, South African men present lower wrinkles/texture, pigmentation, and ptosis/sagging scores till 50-59years, albeit not much different in the cheek pores sign. The early onset (mean age) of visibility of wrinkles/texture for South African men were (i.e., reaching grade >1) 39 and 45years for ptosis/sagging. This study completes and enlarges the previous works conducted on men of other ancestries by showing some South African specificities and slight differences with men of comparable phototypes (Afro American).

Treatment of skeletal classIII malocclusion using acombined clear aligner and surgery-early approach : Assessment based on the American Board of Orthodontics Objective Grading System.

To evaluate whether clear aligner therapy (CAT) combined with asurgery-early approach can achieve good therapeutic effects in patients with skeletal classIII malocclusion. Thirty consecutive skeletal classIII malocclusion cases treated with clear aligners combined with early surgery were selected. Treatment time, lateral cephalograms and American Board of Orthodontics Objective Grading System (ABO-OGS) scores of the treatment models were measured to evaluate the treatment efficiency, facial profile, and occlusion. The results showed that early surgery was achieved after 7.71months of presurgical orthodontics, on average. ANB decreased by 5.57° (P < 0.001), and STissueN Vert to Pog' decreased by 7.29 mm (P = 0.001), both reaching normal values. The posttreatment ABO-OGS scores were 26.600 on average, meeting its standards. With the assistance of CAT, early surgery can be accomplished in patients with skeletal classIII malocclusion, improving their facial profile and achieving functional occlusion.

The sagittal evaluation and classification of midfacial morphology in Chinese Han Youth: A cross-sectional study

Midface is located in the central area of the facial region and plays a crucial role in the aesthetic evaluation of one's appearance. The East Asian, especially the Chinese, has wide and flat midfacial bone structure, low piriform aperture area compared with the prominent zygomatic and oral region, which results in an unpleasant appearance. 1 Jin H.R. Won T.B. Rhinoplasty in the Asian Patient. Clin Plast Surg. 2016; 43: 265-279 Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar In contrast to the patients' surging demand of midface filling surgery, there is a lack of evaluation standard for midfacial depression, nor quantitative and objective grading system for midface morphology. In the current study, we collected the three-dimensional (3D) facial information of Chinese Han Youth and summarized the morphological characteristics of their midface, focusing on the concavity and convexity from the sagittal plane.

Conventional and self-ligating lingual orthodontic treatment outcomes in Class I nonextraction patients: A comparative study with the American Board of Orthodontics Objective Grading System

This study aimed to assess and compare the duration and outcomes of orthodontic treatment with conventional and self-ligating lingual fixed appliances with the American Board of Orthodontics (ABO) Objective Grading System. Thirty consecutive patients with a complete dentition and Angle Class I malocclusion treated with a conventional lingual bracket system (STb; Ormco, Glendora, Calif) or self-ligating lingual bracket system (GC Experience-L; GC Orthodontics, Breckerfeld, Germany) were included. The occlusal outcome was assessed with the ABO instrument. The treatment duration and ABO scores of the 2 groups were recorded. Statistical analyses were evaluated using independent-sample t tests. The conventional group had a mean treatment time of 2.10 ± 0.69 years, and the self-ligating group had a treatment duration of 1.68 ± 0.48 years (P>0.05). The mean posttreatment ABO scores in the conventional group were 20.23 ± 5.13, and the mean posttreatment ABO scores in the self-ligating group were 21.00 ± 5.66. No difference was found between the groups regarding the criteria of ABO (P>0.05). The highest scores were given in the assessment of buccolingual inclinations in both conventional and self-ligating lingual bracket groups. The design of the lingual appliances used in this study did not influence the treatment duration and the total ABO scores in treating patients with a Class I relationship in this sample. Both types of lingual brackets were especially deficient in correcting buccolingual inclinations. The strengths were their ability to close spaces and correct anterior rotations and overjet regardless of the bracket types.

Orthodontic treatment of substituting third molars for missing permanent molars

This study aimed to evaluate the orthodontic effect and efficiency of substituting third molars for missing first or second permanent molars systematically. Forty-six patients (69 third molars total) with missing permanent molars replaced by third molars were selected. The angulation, crown-to-root ratio, and periodontal condition of the third molars before and after treatment were compared. The American Board of Orthodontics Objective Grading System was used to evaluate the alignment and occlusion of third molars after treatment. The duration of orthodontic treatment and third molar replacement therapy were also recorded. The average orthodontic treatment time was 33.9 ± 5.6 months, and the average angulation change of third molars during treatment was 49.8 ± 29.8°. The average height of mesial alveolar bone increased by 4.8 ± 0.5 mm in patients whose third molars were mesially inclined or horizontally impacted. The root length of adult patients decreased by 0.72 ± 0.02 mm on average, and the average gingival recession was 0.10 mm, both of which were not statistically significant. The average score for each third molar evaluated by the American Board of Orthodontics Objective Grading System was 1.8 ± 0.5 points. If the indications and timing of treatment were well-controlled, third molars would be excellent substitutes for missing first or second permanent molars through the orthodontic method.

Agreement evaluation of the severity of oral epithelial dysplasia in oral leukoplakia

Objective: To evaluate the inter-observer agreement of the severity of oral epithelial dysplasia in oral leukoplakia, providing a theoretical basis for the development of a more objective grading system. Methods: This study included 60 digital pathological slides of oral leukoplakia from Oral Medicine Department of West China Hospital of Stomatology, Sichuan University, and 239 tissue microarray images of oral leukoplakia from State Key Laboratory of Oral Diseases, Sichuan University, to evaluate the agreement of grading. Besides, 1 000 patches were generated from the 60 digital pathological slides and were divided into 500 small-sized patches (224 pixel×224 pixel) and 500 large-sized patches (1 024 pixel×1 024 pixel), to evaluate the agreement of feature detection. Gradings and feature detections were completed by three pathological experts from the oral pathology departments of two Grade 3, Class A stomatological hospitals in China. Kappa coefficient was used to quantify the inter-observer agreement among pathologists. Results: Minimal agreement was found in the grading of oral epithelial dysplasia among pathologists (Kappa=0.30 in the pathological slide group, Kappa=0.30 in the tissue microarray group). None agreement was found in feature detection within the small-sized patches group (median Kappa=0.14 for architectural features, median Kappa=0.18 for cytological features), and minimal agreement was found in feature detection within the large-sized patches group (median Kappa=0.25 for architectural features, median Kappa=0.25 for cytological features). Conclusions: Generally, the agreement of grading and feature detection of oral epithelial dysplasia in oral leukoplakia is poor. Development of a more objective grading system of oral epithelial dysplasia based on artificial intelligence may be helpful to improve the agreement.

“Introduction of a low-cost and automated four-dimensional assessment system of the face.”

Existing automated objective grading systems either fail to consider the face's complex three-dimensional morphology or have poor feasibility and usability. Consumer-based red, green, and blue depth sensors or smartphone integrated three-dimensional hardware can inexpensively collect detailed four-dimensional facial data in real time but are yet to be incorporated into a practical system. This study aimed to evaluate the feasibility of a proof-of-concept automated four-dimensional facial assessment system using a red/green/blue depth sensor (OpenFAS) for use in a standard clinical environment. This study was performed on healthy adult volunteers and patients with facial nerve palsy. The setup consists of the Intel (Santa Clara, Calif.) RealSense SR300 connected to a laptop running the OpenFAS application. The subject sequentially mimics the facial expressions shown on screen. Each frame is landmarked and automatic anthropometric calculations are performed. Any errors during each session were noted. Landmarking accuracy was estimated by comparing the ground-truth position of landmarks annotated manually with those placed automatically. Eighteen participants were included in the study, nine healthy participants and nine patients with facial nerve palsy. Each session was standardized at approximately 106 seconds. A total of 61.8 percent of landmarks were automatically annotated within approximately 1.575 mm of their ground-truth locations. The findings support that OpenFAS is usable and feasible in routine settings, laying down the critical groundwork for a facial assessment system that addresses the shortcomings of existing tools. The iteration of OpenFAS presented in this study is nascent; future work, including improvements to landmarking accuracy, analyses components, and red/green/blue depth technology, is required before clinical application.

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19.

The incidence of dry eye syndrome (DES) has increased due to wearing masks, utilizing digital devices, and working remotely during the pandemic. A survey was conducted during the COVID-19 pandemic to determine the prevalence of dry eye syndrome. A cross-sectional study investigated how prevalent DES is during COVID-19 in healthy patients aged 20-45 in the United States. An Ocular Surface Disease Index (OSDI) questionnaire was given to 40 individuals remotely from October 31, 2021, to December 1, 2021. The AOS and the OSDI survey were used to evaluate DES. The subjects were 29 years old on average (SD 14.14), with 23 males (57.5%) and 17 females (42.5%). According to the OSDI survey, low DES, moderate DES, and severe DES had prevalence rates of 15%, 77.5%, and 7.5%, respectively. White (W) people represent 50% of the population, while African Americans (AA) represent 35%, Asians represent 7.5%, and Hispanics represent 7.5%. Mild DES affected 77.5% of subjects, with 64.50% males and 35.50% females. According to the AOS objective grading system, mild (M) DES, moderate (MO) DES, and severe (S) DES had prevalence rates of 40%, 12.5%, and 15%, respectively. Linear regression was used to compare the two grading systems, and it demonstrated a strong relationship between the two grading systems.

Medium Definition Liposuction Abdominoplasty.

Background:Not all patients who exercise regularly and follow a balanced diet will obtain a well-defined abdomen. Medium definition liposuction, together with the removal of abdominal skin, can recreate an adequate connection between the skin/subcutaneous components and the myo-aponeurotic layer, resulting in the perception of muscle definition.Methods:Over a period of 36 months, 351 patients underwent medium definition liposuction associated with abdominoplasty performed by a single surgeon (G.B.). All patients underwent an evaluation through digital photographs by two independent senior plastic surgeons, using an objective grading system for aesthetic outcomes proposed by Strasser, 12 months after the operation.Results:According to the Strasser Scale, 326 patients (93%) were considered to have good and excellent results. Twenty-two patients (6.2%) had moderate/mediocre results‚ and three patients (0.8%) had poor results. The overall complication rate was 4.8%.Conclusion:Medium definition liposuction associated with abdominoplasty has been shown to be effective, safe, and reproducible for most patients.

Dental, skeletal, and soft-tissue changes in adult orthodontic patients treated with premolar extraction and nonextraction: A cross-sectional study

Various treatment modalities exist to improve and correct Class I malocclusion. This study evaluated the dental, skeletal, and soft-tissue changes in patients treated by premolar extraction (PME) and nonextraction. A cross-sectional study was conducted, including subjects ideally planned for PME. Pretreatment and posttreatment lateral cephalograms were compared among the 2 groups. The American Board of Orthodontics Objective Grading System (ABO-OGS) was used to score the posttreatment casts, and soft-tissue profile silhouettes were judged by a panel of orthodontists to evaluate the improvement among the 2 groups. Comparisons between the 2 groups were performed using the Mann-Whitney U test.Spearman correlation was used to study the correlation between the assessment methodologies. Highly significant differences were observed between the 2 groups for ABO-OGS scores (P≤0.001) and profile silhouette assessment (P≤0.001). Compared with posttreatment cephalometric readings, highly significant differences were seen for the dental variables: SN-U1, IMPA, and interincisal angle (P≤0.001). Statistically significant differences were seen for all soft-tissue cephalometric variables. Highly significant moderate to negative correlation (r= -0.410, P≤0.001) was seen between profile silhouettes and ABO-OGS alignment scores. Highly significant strong negative correlation (r= -0.642, P≤0.001) was seen between profile silhouettes and the lower lip. Dental and soft-tissue changes were highly significant and were found to be in the ideal range when treated with PME. However, PME and nonextraction treatment modalities did not significantly affect the skeletal parameters as seen on the lateral cephalogram.

Did the coronavirus disease 2019 pandemic affect orthodontic treatment outcomes? A clinical evaluation using the objective grading system and Peer Assessment Rating index

IntroductionThis study aimed to compare the treatment outcome of patients whose orthodontic treatment was completed before or during the coronavirus disease 2019 pandemic.MethodsPretreatment and posttreatment models of 100 patients treated with fixed orthodontic appliances were evaluated using the peer assessment rating (PAR) index. Posttreatment models and panoramic radiographs were measured and scored with the objective grading system (OGS). All patients had their treatment plans before the coronavirus disease 2019 pandemic, but the orthodontic treatment finishing date was before (prepandemic: group 1, n = 50) or during (pandemic: group 2, n = 50) the pandemic. Intergroup comparisons were tested with an independent samples t test or Mann-Whitney U test. Chi-square test statistics and Fisher exact test were used to compare categorical variables.ResultsSignificant higher posttreatment weighted maxillary alignment score was found in group 2. However, no significant difference was found between the groups concerning the mean total weighted PAR reduction (29.8 ± 9.9 vs 25.6 ± 8.7) and posttreatment total weighted PAR scores (1 vs 2). The PAR index score improvement (%) was similar between the groups (93.7 ± 7.1 vs 89.9 ± 13.0). No statistically significant difference was found between the groups for the total OGS score (32 vs 33). A lower score for marginal ridge height (4 vs 3) and a higher score for buccolingual inclination (7 vs 11), and a lower score for occlusal relationship (3 vs 1) were found in group 2. Canceled appointments (1.1 ± 0.7 vs 4.8 ± 1.6) and the number of missed appointments (0.6 ± 0.5 vs 1.1 ± 0.8) were statistically higher in group 2, whereas the total number of appointments (27.3 ± 8.8 vs 21.8 ± 5.4) were statistically less. The treatment duration was comparable in both groups.ConclusionsReduced and irregular appointments during the pandemic resulted in significantly higher posttreatment weighted maxillary alignment and worsening of the buccolingual inclination. However, the PAR score improvement, total OGS score, and treatment duration were not affected.

Objective and automatic grading system of facial signs from selfie pictures of South African women: Characterization of changes with age and sun-exposures.

To evaluate the capacity of the automatic detection system to accurately grade, from smartphones' selfie pictures, the severity of fifteen facial signs in South African women and their changes related to age and sun-exposure habits. A two-steps approach was conducted based on self-taken selfie images. At first, to assess on 306 South African women (20-69 years) enrolled in Pretoria area (25.74°S, 28.22°E), age changes on fifteen facial signs measured by an artificial intelligence (AI)-based automatic grading system previously validated by experts/dermatologists. Second, as these South African panelists were recruited according to their usual behavior toward sun-exposure, that is, nonsun-phobic (NSP, N=151) and sun-phobic (SP, N=155) and through their regular and early use of a photo-protective product, to characterize the facial photo-damages. (1) The automatic scores showed significant changes with age, by decade, of sagging and wrinkles/texture (p<0.05) after 20 and 30 years, respectively. Pigmentation cluster scores presented no significant changes with age whereas cheek skin pores enlarged at a low extent with two plateaus at thirties and fifties. (2) After 60 years, a significantly increased severity of wrinkles/texture and sagging was observed in NSP versus SP women (p<0.05). A trend of an increased pigmentation of the eye contour (p=0.06) was observed after 50 years. This work illustrates specific impacts of aging and sun-exposures on facial signs of South African women, when compared to previous experiments conducted in Europe or East Asia. Results significantly confirm the importance of sun-avoidance coupled with photo-protective measures to avoid long-term skin damages. In inclusive epidemiological studies that aim at investigating large human panels in very different contexts, the AI-based system offers a fast, affordable and confidential approach in the detection and quantification of facial signs and their dependency with ages, environments, and lifestyles.

Predictors of laminitis development in a cohort of nonlaminitic ponies.

Quantifying risk factors for laminitis development requires improvement. To identify the most useful physical examination, metabolic and management factors to predict laminitis development in client-owned, nonlaminitic ponies. Prospective cohort study. Physical examination, metabolic and management data were collected from a pony cohort 6 monthly for up to 4years. Ponies were monitored for the development of laminitis. Metabolic data included basal plasma concentrations of ACTH ([ACTH]), adiponectin ([adiponectin]), triglycerides and glucose. Serum insulin concentrations ([insulin]) were measured in the unfasted basal state ([insulin]T0) and 60minutes ([insulin]T60) after administration of corn syrup (0.3ml/kg). Separate multivariable Cox proportional-hazards models were developed for physical, management/signalment and metabolic data and later combined into two final models. Low-, medium- and high-laminitis risk categories were defined based on basal or T60 [insulin]. Overall, 374 ponies (age 5-32years) and 891 pony-years were included in the main analysis. Laminitis incidence (95% confidence interval (CI)) was 4.8 (3.5-6.5) cases/100 pony-years. Laminitis development was associated with numerous univariable factors. Significant (P<.05) factors retained in the final multivariable models included [insulin]T0, [insulin]T60, [adiponectin] and divergent hoof growth. [ACTH] was not independently associated with laminitis. Based on [Insulin]T0, low- (<21.6 µIU/ml), medium- (21.6-45.2 µIU/ml) and high-risk (>45.2µIU/ml) categories encompassed 70, 20 and 10% of the population and had estimated 4-year laminitis incidences (95%CI) of 6 (2-9)%, 22 (10-33)% and 69 (48-82)% respectively. Based on [Insulin]T60 the low- (<53.4µIU/ml), medium- (53.4-153µIU/ml) and high-risk (≥153µIU/ml) categories comprised 60, 30 and 10% of the population and had estimated 4-year laminitis incidences (95%CI) of 3 (0-6)%, 20 (10-29)% and 73 (52-84)% respectively. Results may not apply to different insulin assays, geographical regions, breeds or management types. [Insulin]T0 or [insulin]T60 best quantify the risk of future laminitis development in nonlaminitic ponies.

Linear and angular transfer accuracy of labial brackets using three dimensional-printed indirect bonding trays: A systematic review and meta-analysis

To assess the transfer accuracy of three dimensional-printed trays (3D-printed trays) and to compare the accuracy of this approach with the other methods used for the same purpose. An electronic search was performed in PubMed, Scopus, Web of science, Google Scholar and ProQuest (dissertation and theses). Studies were eligible for inclusion if they involved the assessment of transfer errors measured by the superimposition of the original set-up of brackets and the final positions after transfer. Risk of bias was assessed using Cochrane's tools. Seven studies were included. The pooled estimate of the transfer error in the linear dimensions showed an error of 0.095mm in the mesiodistal direction (95%CI: 0.035, 0.155), 0.114mm in the buccolingual direction (95%CI: 0.067, 0.160) and 0.111mm in the vertical direction (95%CI: -0.033, 0.255). Concerning the angular dimensions, the pooled estimate showed a tipping error of 1.3420 (95%CI: 0.444, 2.240), rotational error of 0.9980 (95%CI: 0.323, 1.672), and torque error of 1.9130 (95%CI: 0.922, 2.903). Thus, the maximum transfer error was in the bucco-lingual and torque directions. 3D-printed trays had better control in mesiodistal and vertical directions than vacuum-formed trays. Polyvinyl siloxane trays were more accurate in the vertical direction than 3D-printed trays. The scarcity of randomized clinical trials is the main risk of bias of the included studies. According to the available evidence, 3D-printed trays have an acceptable transfer accuracy, based on the American Board of Orthodontics Objective Grading System (ABO OGS), with maximum linear transfer error in the buccolingual direction and maximum angulation error in the torque. Conducting randomized clinical trials on this topic is highly recommended.

American Board of Orthodontics (ABO) Discrepancy Index and peer assessment rating (PAR) index with models versus photographs

BackgroundThe objectives of this study were to determine whether rating systems, such as the Peer Assessment Rating (PAR) and the American Board of Orthodontics Objective Grading System (ABO-OGS) can be applied to intraoral photographs. MethodsModels and photographs of 50 cases were graded by 4 raters, and a 20% repeat of randomized cases was completed 2 weeks later. Intraclass correlation coefficients (ICCs) were used to assess inter- and intra-rater agreements, as well as the level of agreement between the ratings on models and photographs. ResultsThe intra- and inter-rater agreements were considered good to excellent. The paired mean difference (model minus photo) for the PAR index and the ABO Discrepancy Index as a total was 2.405 and 1.156, respectively. Overjet was the subdomain that produced the highest differences between photos and models. The ABO- Discrepancy Index method on photographs was more reliable than the PAR index when grading pre-treatment and more-severe malocclusions. ConclusionsBoth methods can be used, but the choice depends on the purpose of the evaluation, and on consideration of the weaknesses and strengths of each relating to its use on photographs.

Reliability of a digital system for models measurements in BBO grading: A pilot study.

ABSTRACTIntroduction: Currently, no method is considered effective for the evaluation of digital models in the Certification Examination of the Brazilian Board of Orthodontics (BBO), considering the parameters of the currently used manual method. Objective: Thus, the aim of this study is to verify the reliability of an evaluation method for digital models that could be used in the BBO exam, compared to the gold standard.Methods: Measurements were performed by five previously calibrated examiners. Samples of ten sets of plaster models of the final phase of orthodontic treatment were measured using a manual method (Objective Grading System, OGS). These models were digitized using a 3D scanner and exported to Geomagic Qualify software, in which the measurements were made with the proposed digital method. These measurements were repeated using five models, after fifteen days. The intra-examiner performance with this method was analyzed with a paired t-test, whereas the inter-examiner analysis was carried out with analysis of variance and Tukey’s test. To compare the manual and digital methods, a paired t-test and Pearson’s correlation analysis were performed.Results: A statistically significant difference was found. The results showed that, when compared to the manual method, the digital method was effective in measuring the OGS in four of the seven variables studied: Marginal Ridge, Overjet, Occlusal Contact, and Interproximal Contact. The variables Alignment, BL inclination, and Occlusal Relationship showed a great amount of dispersion in the findings.Conclusion: Further studies are needed to develop an adequate digital methodology that can be used for all OGS variables.