Objective Evaluation Research Articles

Screening of Sensorial and Inflammatory Changes in Patients Submitted to Orthognathic Surgery.

Despite the high levels of success after orthognathic surgery, the immediate postoperative pain and edema, besides the neurosensorial deficits, are common complications. This study aimed to evaluate the pattern of sensory and inflammatory responses in patients undergoing orthognathic surgery. This prospective observational study included 20 patients undergoing bimaxillary orthognathic surgery, who were evaluated in the preoperative period and on Days 1, 2, 3, 4, 5, 6, 7, and 30 after surgery, using a battery of tests to assess sensorial and inflammatory changes. Subjective and objective evaluations of edema indicated a trend toward edema resolution within 30 days, with a significant decrease in mouth opening on days 1, 7, and 30 after surgery. Regarding nasal obstruction, a significant increase in Nasal Obstruction Symptom Evaluation (NOSE) scores was demonstrated on the first, second, and third days, returning to preoperative levels after 30 days. There was a significant increase in visual analogic scale (VAS) scores from the first to the seventh day after surgery, with a reduction within 30 days. For mechanical and thermal sensitivity tests, the lower lip and chin regions had poorer results, without recovery after 30 days. Positive correlations were observed between painful and inflammatory parameters, as well as between subjective and objective evaluations. Analysis of saliva biomarkers did not show significant differences for pre- and postoperative CCL3 or CCL4 levels. Data provide new evidence about the early inflammatory and sensorial complications after orthognathic surgery.

‘Goalkeepers are players too’: key attributes coaches’ look for in talented youth soccer goalkeepers

ObjectiveCurrently, there is a gap in knowledge on what the key goalkeeper attributes are during talent identification and selection in soccer. Hence, the objective was to investigate South African coaches’ perceptions regarding key attributes of talented youth soccer goalkeepers.DesignCross-sectional survey.MethodsA total of 173 soccer coaches (130 men and 43 women; Mage = 36.6 ± 10.4 years; Mcoaching experience = 8.4 ± 7.3 years) were purposively recruited to participate in the study. All of the participants completed the Talent Identification Questionnaire in Soccer – Goalkeepers (TIDQS-GK).ResultsThe six-component solution identified by the principal component analysis accounted for 68.96% of the total variance. Coaches deemed psychological (e.g. concentration, bravery, self-discipline), physical (e.g. speed, flexibility), social (e.g. coachability, communication), technical (e.g. catching the ball, first touch), tactical (e.g. defensive organisation against set plays) and perceptual-cognitive skills (e.g. decision-making) as important factors in identifying talented goalkeepers.ConclusionsThe study offers new insights into the key attributes that soccer coaches look for in talented goalkeepers such as concentration, bravery, speed, coachability and decision-making and could direct coaches towards more objective evaluation strategies for informing their decisions.

An Operations Chain Model for Automatic Assessment of Operation Procedure for Equipment Operators

Automatic assessment of the operation ability of operators based on computers is an essential approach for improving the effectiveness of equipment operation training and enhancing equipment safety. Present methods primarily focus on the operation results but pay less attention to the operation procedure. One reason is that there is a lack of a model that has the ability to describe all probable paths to accomplish the same task. Therefore, an operations chain model is put forward for the first time to describe the standard operation procedure and relationships among operations based on the decomposition of operational tasks and the relationships among the various operations required to fulfill the task. A specific operation task corresponds to an operations chain, which will form one or multiple standard operation sequences that will allow trainees to complete the same task through different paths. The Needleman–Wunsch sequence alignment algorithm is introduced to match the trainees’ operation sequence with all standard sequences. The maximum alignment result is the score of the trainees’ operations. An example shows that the operations chain model can accurately describe the complex structure of the standard operating procedures. The Needleman–Wunsch sequence alignment algorithm can objectively evaluate the trainee’s operation capabilities. The combination of the operations chain model and sequence alignment algorithm can form a complete operation procedure assessment method that is friendlier to trainees and has more objective evaluation results. The method will help to improve the effectiveness of the competency assessment of equipment operators.

Longitudinal monitoring of hypertonia through a multimodal sensing glove

As clinical evaluations of neuromuscular disorders such as hypertonia mostly rely on perception-based scales, the imprecise subjective ratings make it difficult to accurately monitor treatment progress. To promote objective evaluation, this work used a multi-modal sensing glove in a double-blind study to enable sensitive monitoring of medication effects across 19 participants. The biomechanical measurements from the sensing glove effectively distinguished patient cohorts receiving a baclofen treatment or a placebo with 95% confidence. Consistent monitoring over a two-month period was demonstrated, closely tracking variations in individual responses to treatment. The biomechanical changes were correlated to neural activities as recorded by electromyography, verifying the medication effects. The sensing glove is shown to be a reliable tool for point-of-care settings to facilitate precise evaluation of hypertonia, essential for tailoring individual treatment choices and timely management of chronic symptoms.

Subjective and objective evaluation of nasal obstruction in patients treated at the Hospital de Clínicas, Paraguay

Nasal obstruction is characterized by insufficient airflow and increased resistance in the nasal cavities, affecting patients’ quality of life and sleep. This study aims to compare the efficacy of medical and surgical treatment in patients with Nasal obstruction, using subjective evaluations (NOSE and VAS scales) and objective evaluations (active anterior rhinomanometry). This is an experimental and prospective longitudinal study conducted at the Hospital de Clínicas, Paraguay. Forty patients with Nasal obstruction were included, divided into medical treatment (nasal corticosteroids) and surgical treatment (turbinoplasty, septoplasty, or both) groups. Pre- and post-treatment evaluations were performed using the NOSE and VAS scales, and active anterior rhinomanometry. The sample included 52.5% men and 47.5% women, with an average age of 32.18±11.59 years. The main cause of Nasal obstruction was chronic rhinitis (62.5%). Treatments showed significant improvements in subjective and objective evaluations. In the medical group, VAS improved by 2.63 points in women and 2.00 in men, while the surgical group showed more pronounced improvements. The NOSE also showed significant reductions, especially in patients undergoing combined turbinoplasty and septoplasty. Active anterior rhinomanometry reflected an increase in overall nasal flow in all treated groups. Both medical and surgical treatments are effective in improving Nasal obstruction, with greater benefits observed in surgical treatments. Subjective and objective evaluations are valuable and complementary tools for assessing treatment in patients with Nasal obstruction. These results highlight the importance of a comprehensive evaluation in the management of Nasal obstruction.

Subjective and objective quality evaluation for industrial images

Recently, the demand for ever-better image processing technique continues to grow in field of industrial scenario monitoring and industrial process inspection. The subjective and objective quality evaluation of industrial images are vital for advancing the development of industrial visual perception and enhancing the quality of industrial image/video processing applications. However, the scarcity of publicly available industrial image databases with reliable subjective scores restricts the development of industrial image quality evaluation (IIQE). In preparation for a vacancy, this article first establishes two industrial image databases (i.e., industrial scenario image dataset (ISID) and industrial process image dataset (IPID)) for assessing IIQE metrics. Furthermore, in order to avoid overwhelming industrial image nuances due to the wavelet subband summation, we then present a novel industrial application subband information fidelity standard (SIFS) evaluation method using the channel capacity of visual signals in wavelet domain. Specifically, we first build a visual signals channel model based on perception process from human eyes to brain. Second, we compute and compare the channel capacity for reference and distorted images to measure the information fidelity in each wavelet subband. Third, we sum over the subbands for information fidelity ratio to obtain the overall quality score. Finally, we fairly compare some up-to-date and our proposed image quality evaluation (IQE) methods in two novelty industrial datasets respectively. Our ISID and IPID datasets are capable of evaluating most IQE metrics comprehensively and paves the way for further research on IIQE. Our SIFS model show a remarkable performance comparing with other up-to-date IQE methods.

Specific training in coloproctology: cross-sectional cohort study through the Young Group of the Spanish Association of Coloproctology

IntroductionSpecific training at surgical super-specialities and its objective evaluation is a challenge nowadays in order to measure the potential benefits that it might add. Material and methodsAn online survey addressed by the “Grupo Joven de la Asociación Española de Coloproctología” has been performed in order to evaluate the level of formation achieved specifically at colorectal surgery. Results128 surgeons participated, representing 81 colorectal surgery units. Mean satisfaction after the period of formation was moderate to high in 84% of the ones polled. The main points of improvement were the realization of advanced surgical techniques (52%) and academic questions (45%). The big part of the respondents has performed simple proctologic procedures (98%) and oncological open colic resections (100%) during their training period, observing the scarcity of related pelvic floor procedures (20%) and diagnosis techniques (10–45%). Scientific production (31,5%) and presentation of studies at congresses (82,8%) have been moderated. No differences between accredited units and non-accredited units have been observed. ConclusionsSpecific formation in colorectal surgery is appropriate, with a high level of simple procedures and open surgery performed by personal at formation. In view of these results, it seems logical to think that even though is necessary a progress in the formation of minimal invasive and diagnosis techniques.

Feeling senseless sensations: a crossmodal EEG study of mismatched tactile and visual experiences in virtual reality

Objective.To create highly immersive experiences in virtual reality (VR) it is important to not only include the visual sense but also to involve multimodal sensory input. To achieve optimal results, the temporal and spatial synchronization of these multimodal inputs is critical. It is therefore necessary to find methods to objectively evaluate the synchronization of VR experiences with a continuous tracking of the user.Approach.In this study a passive touch experience was incorporated in a visual-tactile VR setup using VR glasses and tactile sensations in mid-air. Inconsistencies of multimodal perception were intentionally integrated into a discrimination task. The participants' electroencephalogram (EEG) was recorded to obtain neural correlates of visual-tactile mismatch situations.Main results.The results showed significant differences in the event-related potentials (ERP) between match and mismatch situations. A biphasic ERP configuration consisting of a positivity at 120 ms and a later negativity at 370 ms was observed following a visual-tactile mismatch.Significance.This late negativity could be related to the N400 that is associated with semantic incongruency. These results provide a promising approach towards the objective evaluation of visual-tactile synchronization in virtual experiences.

Monoenergetic reconstructions and iodine density maps for visualization of coronary artery stents using 8-cm dual-layer detector spectral computed tomography: an in vitro phantom study.

The effectiveness of coronary computed tomography (CT) angiography in assessing stent restenosis is hindered by heavy metal artifacts. This study aimed to evaluate the image quality of monoenergetic reconstructions and iodine density map for coronary stent imaging using an 8-cm dual-layer detector spectral CT. In this study, 8 stents with a diameter <3 mm (group A) and 10 with a diameter ≥3 mm (group B) were placed in plastic tubes filled with iodinated contrast media and scanned. The internal diameter of the prepared stents was then measured by intravascular ultrasound. The reconstructed images included iodine density maps, conventional images, and different energy levels. The visualization of the stent lumen and stent structure was subjectively assessed using a 4-point Likert scale. The objective evaluation was performed using the in-stent lumen signal-to-noise ratio (SNRis), non-stent lumen SNR (SNRns), internal diameter difference (IDD), and blooming artifact index (BAI). The Friedman test and analysis of variance were used for multiple comparisons. For lumen visualization, the optimal monoenergetic images received the highest score for both group A (2.56±0.51) and group B (3.1±0.55). Multiple comparisons showed that there were significant differences between the optimal monoenergetic images and iodine density maps. However, for stent structure, iodine density maps received the highest score for group A (3.0±0.52) and group B (3.8±0.41). For quantitative assessment, the optimal monoenergetic images had the highest SNRis and SNRns, while the iodine density maps had the lowest SNRis and SNRns. For IDD and BAI, the iodine density maps yielded the smallest value. The monoenergetic images on the second-generation dual-layer detector CT provide better visualization of the lumen and higher SNR. However, iodine density maps are superior for evaluating stent structure and IDD and BAI compared to monoenergetic and conventional reconstructions.

MHW-GAN: Multidiscriminator Hierarchical Wavelet Generative Adversarial Network for Multimodal Image Fusion.

Image fusion technology aims to obtain a comprehensive image containing a specific target or detailed information by fusing data of different modalities. However, many deep learning-based algorithms consider edge texture information through loss functions instead of specifically constructing network modules. The influence of the middle layer features is ignored, which leads to the loss of detailed information between layers. In this article, we propose a multidiscriminator hierarchical wavelet generative adversarial network (MHW-GAN) for multimodal image fusion. First, we construct a hierarchical wavelet fusion (HWF) module as the generator of MHW-GAN to fuse feature information at different levels and scales, which avoids information loss in the middle layers of different modalities. Second, we design an edge perception module (EPM) to integrate edge information from different modalities to avoid the loss of edge information. Third, we leverage the adversarial learning relationship between the generator and three discriminators for constraining the generation of fusion images. The generator aims to generate a fusion image to fool the three discriminators, while the three discriminators aim to distinguish the fusion image and edge fusion image from two source images and the joint edge image, respectively. The final fusion image contains both intensity information and structure information via adversarial learning. Experiments on public and self-collected four types of multimodal image datasets show that the proposed algorithm is superior to the previous algorithms in terms of both subjective and objective evaluation.

Основные принципы фактической , реальной критики Н.А.ДобролюбоваДоктор доцент Ибтисам Ахмед Хамза

This research is dedicated to analyzing the criticism of N. A. Dobrolyubov and examining his critical approach. Dobrolyubov founded his realistic criticism on a profound understanding of life and literature. His criticism was objective and independent, significantly influencing the development of Russian literature. Dobrolyubov believed that criticism should be based on facts and objective evaluation. He analyzed literary works in terms of their intellectual content, artistic characteristics, and social functions. Dobrolyubov asserted that literature should be active and aimed at societal development, and he criticized works that, in his view, did not reflect the life of society or contribute to its progress. His realistic criticism had a major impact on the development of Russian literature, contributing to the formation of realism in Russian literature as well as the development of social thought in Russia. According to him, realistic criticism is based on the realistic analysis of literary works, rather than the subjective impressions of the critic.

Use of the Oral Sialogogue “Oriza Tablet” in Reducing Drug-Induced Xerostomia in Patients with Overactive Bladder or Neurogenic Bladder: Randomized Clinical Study

Purpose Evaluate the clinical efficacy of “Oriza tablet” (OT) for patients with neurologic bladder or overactive bladder affected by xerostomia due to receiving antimuscarinic drugs. Material and methods This was a randomized clinical trial. Twenty-eight patients (median age = 64 years) with xerostomia were divided into two groups: OT (intervention group) and placebo (control) group. Both groups comprised 14 patients each. Objective We assessed severity using a questionnaire for the subjective evaluation of xerostomia. Objective evaluation was undertaken for the stimulated salivary flow rate (SSFR). Xerostomia evaluation took place before treatment (baseline) as well as 2 weeks and 4 weeks after treatment. Results The xerostomia score decreased significantly ( p &lt; 0.05) in the OT group compared to the placebo group, with scores of 2.75 versus 4.4 at 2 weeks and 2.19 versus 4.13 at 4 weeks, respectively. The SSFR increased significantly ( p &lt; 0.05) in the OT group compared to the placebo group, with SSFR of 2 versus 1.2 at 2 weeks and 1.85 versus 1.1 at 4 weeks, respectively. Throughout the trial, no patient discontinued taking antimuscarinic medications. There were no adverse effects noted. Conclusion Continuous daily use of OT for 4 weeks reduced xerostomia symptoms and increased saliva production in patients suffering from neurologic bladder or overactive bladder who received antimuscarinic medications. Clinical trial registration The study was registered with The Thai Clinical Trials Registry (TCTR). ID: TCTR20240715015.

Improving goal-concordant care via a uniquely collaborative and multi-site PFAC model.

265 Background: Studies reveal a mismatch between the goals of care (GOC) of cancer patients and actual care received. The 10 members of the Alliance of Dedicated Cancer Centers (ADCC) convened the Improving Goal Concordant Care (IGCC) initiative to address system gaps. IGCC was led by palliative care and oncology experts, with guidance from patient and family advisors. Uniquely, the advisors were identified from patient family advisory councils (PFAC) at each center, forming a collaborative Advisory Group (AG) with the lived experience of each center and the knowledge of advocating for the patient/family voice locally. Methods: PFAC members were recruited from each site to serve on the AG. The 19 member AG met quarterly, with minutes shared with the IGCC oversight group, the Implementation Workgroup (IWG). In September 2023, all AG members were surveyed about perceptions of PFAC engagement and local impact of IGCC. In May 2024, 20 IWG members were surveyed about implementation successes and barriers, including items related to PFAC engagement. Results: AG evaluation and recommendations altered IGCC planned core implementation and evaluation actions meaningfully; for example in 1) selection of structured fields in electronic health record (EHR) and universally accessible GOC documentation and in 2) centering patients in the GOC measure set, including incorporating “Heard &amp; Understood” survey into IGCC evaluation. Other AG guidance around direct patient engagement readiness for GOC conversations and implementing patient GOC surveys was left to individual sites to consider with variable adoption. AG Survey: 63% response rate. 80% noted that the GOC program was discussed with their local PFAC and 92% experienced changed routine patient care after GOC implementation. IWG Survey: 100% response rate. 68% agreed that their center sought guidance from their PFAC during GOC implementation and that leadership presented to their PFAC about their GOC implementation. 26% indicated reporting data to their PFAC; of those that did, 80% agreed that this positively impacted their GOC implementation. Conclusions: While PFACs are occasionally included in quality interventions, this model centered the patient/family voice by supporting a PFAC stakeholder feedback loop working collaboratively and locally to support implementation and evaluation of IGCC objectives. While not all AG recommendations were formally integrated into IGCC, all were considered and many adopted at individual centers. Despite ongoing IGCC-level involvement, center-specific engagement of PFACs varied. Future efforts can track this during process evaluation as local PFAC engagement was highly valued. Consensus building for national best practice implementation and evaluation by recruiting local experts including PFAC members into national collaborative efforts is a successful model for local change.

Objective Esthetic Evaluation of Implant-Supported Single Crowns

Objective Esthetic Evaluation of Implant-Supported Single Crowns

Enhancement of joint quality for laser welded dissimilar material cell-to-busbar joints using meta model-based multi-objective optimization

In the battery pack assembly, it is essential to ensure that the cell-to-busbar joints can be produced with high quality and with minimal impact on the individual battery cells. This study examines the influence of process parameters on the joint quality for nickel-plated copper and steel plates, laser welded in an overlap configuration. Artificial neural network-based meta models, trained on numerical results from computational fluid dynamics simulations of the laser welding process, are used to predict and evaluate the joint quality. A set of optimized process parameters is identified, in order to simultaneously maximize the interface width for the joints, and minimize the formation of undercuts and in-process temperatures. In an meta model-based multi-objective optimization approach, the non-dominated sorting genetic algorithm II (NSGA-II) is used to efficiently search for trade-off solutions and the meta models are used for objective approximation. As a result, the objective evaluation time is decreased from around 9 h, when evaluated directly from numerical simulations, to only tenths of a second. From the Pareto-optimal front of trade-off solutions, three optimal solutions are selected for validation. The selected solutions are validated through laser welding experiments and numerical simulations, resulting in joints with large interface widths and low in-process temperatures without a full penetration.

Benefits and Drawbacks of International Medical Elective Databases in Abroad Elective Research: A Narrative Review.

International medical electives (IMEs) are considered high-impact practice in global health education. Nevertheless, international medical elective (IME) research remains scarce, with only a few new publications appearing each year. The discrepancy between the many unanswered questions regarding IMEs and the lack of opportunities to perform research in this field has been further aggravated by the COVID-19 pandemic. Elective databases cataloguing structured IME reports/testimonies could offer a viable solution here. This narrative review provides a balanced and objective evaluation of the strengths and weaknesses of elective databases, summarizing their potential usefulness in IME research. The methodology employed was a multidisciplinary narrative review of the published and grey literature on databases cataloguing IME testimonies. Elective databases offer numerous benefits to the IME researcher. Their size allows for large analyses, built on hundreds of equally structured elective testimonies. Pre-defined outcomes, such as the elective destination, elective discipline or duration, are queried in a standardized way, allowing for a broad set of research questions. Elective databases are usually open-access, not confined to a single university, and free to use. Most databases also offer user-friendly filter functions, permitting targeted analyses centered around a particular outcome. A major drawback is that reports are rarely verified. Subject to several forms of bias (eg, recall and reporting bias), elective databases may not be suitable for all types of research questions, and the report quality is often inhomogeneous. Above all, they rarely allow for an informational depth that may result from qualitative face-to-face interviews. Elective databases could be a valuable supplement to interview-based elective research, potentially allowing for larger and broader analyses not confined to single institutions.

Autologous platelet-rich plasma and fibrin-augmented minced cartilage implantation in chondral lesions of the knee leads to good clinical and radiological outcomes after more than 12 months: A retrospective cohort study of 71 patients.

The treatment of cartilage lesions remains a challenge. Matrix-associated autologous chondrocyte implantation has evolved to become the gold standard procedure. However, this two-step procedure has crucial disadvantages, and the one-step minced cartilage procedure has gained attention. This retrospective study aimed to evaluate the clinical and radiological outcome of an all-autologous minced cartilage technique in cartilage lesions at the knee joint. In this retrospective cohort study, 71 patients (38.6 years ± 12.0, 39,4% female) with a magnetic resonance imaging (MRI) confirmed grade III-IV cartilage defect at the medial femur condyle (n = 20), lateral femur condyle (n = 2), lateral tibia plateau (n = 1), retropatellar (n = 28) and at the trochlea (n = 20) were included. All patients were treated with an all-autologous minced cartilage procedure (AutoCart™). Clinical knee function was evaluated by the Tegner score, visual analogue scale, the subjective and objective evaluation form of the International Knee Documentation Committee and the Knee Injury and Osteoarthritis Outcome Score (KOOS). MRI analyses were performed by magnetic resonance observation of cartilage repair tissue (MOCART) 2.0 knee score. Follow-up examination was 13.7 ± 4.2 (12-24) months postoperative. All clinical scores significantly improved after surgical intervention (p < 0.0001), especially the subgroup sports and recreation of KOOS showed clear changes from baseline in the follow-up examination. In the postoperative MRI evaluation, 39 of 71 patients showed a complete fill of the cartilage defect without subchondral changes in 78% of the patients in the MOCART 2.0 score in the follow-up analysis. None of the patients showed adverse effects, which are linked to the minced cartilage procedure during the time of follow-up. An all-autologous minced cartilage technique for chondral lesions at the knee joint seems to be an effective and safe treatment method with good clinical and radiological short-term results. Level IV.

GNRB® Knee Arthrometer: Inter- and Intra-observer Reliability and Learning Curve.

Background Diagnosing anterior cruciate ligament rupture is challenging, particularly due to the subjective nature of clinical laxity assessments. Objective evaluation methods are necessary for consistency and publication in clinical research. This study aims to assess the reproducibility of the GNRB® knee arthrometer (GeNouRoB, Laval, France) across different examiners and to examine the associated learning curve for a junior examiner. Methods Anterior translation measurements were conducted on 20 healthy knees using the GNRB arthrometer. Two examiners, a senior and a junior, performed the measurements independently and were blinded to each other's results. Measurements were taken at two different push forces (134 N and 200 N). The study evaluated inter- and intra-observer reproducibility using Cohen's kappa coefficient and the intraclass correlation coefficient (ICC). The junior examiner also performed a thirdseries of measurements to assess the learning curve. Results The senior examiner demonstrated excellent reproducibility with an ICC greater than 0.75 for all measurements. The junior examiner's reproducibility varied from fair to good, with an ICC ranging from 0.45 to 0.75. Inter-observer reproducibility between the senior and junior examiners was excellent (ICC >0.75). Notably, the junior examiner's reproducibility improved to an excellent level (ICC >0.75) during the second series of measurements. Conclusion The GNRB system provides a reproducible method for evaluating anterior knee laxity across different examiners. A learning curve of approximately 20 knees is sufficient for a junior examiner to achieve statistically excellent reproducibility.

End‐to‐end speech‐denoising deep neural network based on residual‐attention gated linear units

AbstractIn this letter, an improved gated linear unit (GLU) structure for end‐to‐end (E2E) speech enhancement is proposed. In the U‐Net structure, which is widely used as the foundational architecture for E2E deep neural network‐based speech denoising, the input noisy speech signal undergoes multiple layers of encoding and is compressed into essential potential representative information at the bottleneck. The latent information is then transmitted to the decoder stage for the restoration of the target clean speech. Among these approaches, CleanUNet, a prominent state‐of‐the‐art (SOTA) method, enhances temporal attention in latent space by employing multi‐head self‐attention. However, unlike the approach of applying the attention mechanism to the potentially compressed representative information of the bottleneck layer, the proposed method instead assigns the attention module to the GLU of each encoder/decoder block layer. The proposed method is validated by measuring short‐term objective speech intelligibility and sound quality. The objective evaluation results indicated that the proposed method using residual‐attention GLU outperformed existing methods using SOTA models such as FAIR‐denoiser and CleanUNet across signal‐to‐noise ratios ranging from 0 to 15 dB.

Self-other voice discrimination task: A potential neuropsychological tool for clinical assessment of self-related deficits

BackgroundDeficits in self are commonly described through different neuro-pathologies, based on clinical evaluations and experimental paradigms. However, currently available approaches lack appropriate clinical validation, making objective evaluation and discrimination of self-related deficits challenging. MethodsWe applied a statistical standardized method to assess the clinical discriminatory capacity of a Self-Other Voice Discrimination (SOVD) task. This task, validated experimentally as a marker for self-related deficits, was administered to 17 patients eligible for neurosurgery due to focal hemispheric brain tumors or epileptic lesions. ResultsThe clinical discriminatory capacity of the SOVD task was evident in three patients who exhibited impairments for self-voice perception that could not be predicted by other neuropsychological deficits. Impairments in other-voice perception were linked to inhibitory neuropsychological deficits, suggesting a potential association with executive deficits in voice recognition. ConclusionsThis exploratory study highlights the clinical discriminatory potential of the SOVD task and suggests that it could complement the standard neuropsychological assessment, paving the way for enhanced diagnoses and tailored treatments for self-related deficits.