Introduction- PCOS is a complex metabolic, endocrinopathy and reproductive disorder that results in the production of androgens and is associated with insulin resistance. Adolescents with PCOS are more obese than normal adolescents and have an increased risk of metabolic syndrome. In obese adolescent increasing abdominal adiposity, worsening insulin sensitivity and Dyslipoproteinemiadyslipoproteinemia give rise to NAFLD in adulthood. This study aimed to investigate the association between PCOS, obesity, NAFLD and Metabolic syndrome in adolescents with PCOS. MATERIALAND METHOD- Retrospective study of 24 obese adolescent PCOS patients. with mean BMI 32.89 kg/m2. Data were taken from 1st January 2015 to 31st December 2020. PCOS patients were diagnosed according to Rotterdam 2003 criteria. Data were collected from the medical records of the patients including clinical history, height, weight, blood pressure, waist circumference and Modied Ferriman-Gallway score for hirsutism. Laboratory values were obtained ultrasound nding of polycystic ovarian disease and fatty liver were obtained from the records. RESULTS:- 2 In our study, the mean age was 15.2 yr The mean body mass index was 32.89 kg/m and the mean age of menarche was 12.3 yr. Hirsutism was present in 75% by modied FG Score system, Family history of PCOS was present in 29.16%, Family history of Cardiovascular disease was present in 12.5%. Afamily history of diabetes mellitus was present in 20.83%. The majority 87.5% of the obese adolescent girl's were presented with menstrual problems. mostly 70.83% with a history of Oligomenorrhea. Waist circumference, >0.80 was present in 87.5%, 50% of patients were hypertensive. 20.83% were prediabetes, 54.16% of patients were found to have dyslipidaemia and 45.83% of patients had Metabolic syndrome. In our mean LH was 10.6 IU/L, mean FSH was 5.8 IU/L, mean Serum testosterone 18.5 ng/ml, mean Serum prolactin was 21.2 ng/mL and mean Serum TSH was 3.3 µIU/mL.75 % of patients had Polycystic appearing ovarian morphology in USG.45.83 % of obese PCOS patient had NAFLD in USG and 33.33% of obese patients had abnormal liver enzymes with NAFLD in USG nding. CONCLUSION:-In our study, we found both metabolic syndrome and NAFLD were frequent in patients with obese adolescent PCOS conrming a relevant clinical association between these three conditions. This study highlights the importance of preventing obesity during the management of adolescent PCOS. The importance of obesity counselling in obese adolescent women is a must to reduce the risks associated with metabolic syndrome. The therapeutic intervention combined with lifestyle modication may provide better treatment for adolescent PCOS.