Malnutrition Research Articles

Complementary food hygiene practice and associated factors among mothers with children aged 6–23 months in Dessie Zuria, South Wollo Zone, Amhara, Ethiopia, 2023

BackgroundImplementing appropriate complementary food hygiene practices is essential to lower the incidence of food-borne disease and malnutrition in children. However, this aspect is often overlooked in resource-limited settings, and information regarding these practices is not fully available and is not assessed enough. Therefore, this study aimed to assess complementary food hygiene practices and their associated factors in Dessie Zuria, South Wollo Zone, Amhara, Ethiopia, in 2023.MethodsAn institutional-based cross-sectional study design was conducted from 17 April to 18 May 2023, among 366 mothers with children aged 6–23 months. Dessie Zuria was purposively selected, and a systematic random sampling technique was used to recruit study participants. Data were collected using pretested and structured questionnaires. Finally, the data were entered using EPI-info and then exported to SPSS version 26. Bivariable and multivariable logistic regression analyses were used to identify factors associated with complementary feeding hygiene practices. Both crude odds ratios (COR) and adjusted odds ratios (AOR) with a 95% confidence level (CI) were computed, and a p-value of <0.05, in the final model, was considered statistically significant.ResultsThe proportion of households practicing complementary food hygiene was 22.22%. Factors associated with these practices included access to media such as television or radio (AOR = 10.51, 95% CI: 2.8, 39.28), starting complementary feeding before 6 months (AOR = 2.01, 95% CI: 1.05, 3.84), and the child’s age being 6 to 11 months (AOR = 0.25, 95% CI: 0.08, 0.7).ConclusionThe prevalence of complementary food hygiene practices was poor. Healthcare professionals should promote starting breastfeeding at the age of 6 months. In addition, media companies ought to make an effort to create a positive social and cultural environment that encourages complementary feeding practices for young children.

A Review on Malnutrition in Children: Management and Treatment

Abstract: Malnutrition in children is a major problem in developing countries. An increased number of children are dying because of a lack of nutrition in their regular diet. The nutritional value of food during the growing stage of children is important. The development of the human body requires various types of nutrition for normal growth, which is obtained from a regular healthy diet. In this study, an exhaustive literature survey was done using Pubmed, Google Scholar, and various other internet sources, and also other reference records were studied. This review highlighted the causes and consequences of the perpetual lack of a healthy diet that leads to malnutrition. It also summarized the steps taken for the management and treatment of malnutrition. This review may be a vital tool for the researchers working on malnutrition for its proper understanding.

Optimizing Lumefantrine Dosing for Young Children in High-Malaria-Burden Countries Using Pharmacokinetic-Pharmacodynamic Simulations.

Artemether-lumefantrine is the most widely used treatment for uncomplicated malaria and it is dosed based on weight bands according to World Health Organization (WHO) guidelines. However, children are vulnerable to underdosing. Inadequate dosing can lead to treatment failure and drug resistance. Nutritional parameters for 372 363 children <5 years old in 25 high-malaria-burden countries were acquired from the Demographic and Health Surveys program. Prevalence of attaining day 7 lumefantrine concentrations ≥200 ng/mL and remaining reinfection free for 42 days were evaluated using a simulation-based approach with a population pharmacokinetic-pharmacodynamic model. Besides the WHO-recommended lumefantrine dosing regimen (twice daily for 3 days), we explored 3 adjusted regimens: extended (2 extra days of dosing), increased (1 extra 120-mg tablet per dose), and intensified (thrice daily for 3 days). We also explored an alternative method dosing malnourished children based on expected weight for age. We estimated that 75% of children reached the 200 ng/mL lumefantrine threshold and 77% were malaria free for 42 days when using WHO treatment guidelines. By switching to the alternative dosing method, 5% more children achieved target lumefantrine levels; 22% more achieved the target using the alternative dosing and the extended regimen. With combined alternative plus extended dosing, 97% of children reached 200 ng/mL lumefantrine and 88% were malaria free for 42 days. This study highlights the inadequacies of weight-based lumefantrine dosing for young and underweight children and supports the need of clinical trials using extended dosing based on expected weight in malnourished children.

Modern aspects of therapy of metabolic associated liver disease in patients with type 2 diabetes mellitus

Metabolic associated fatty liver disease (MAFLD) is currently the most common liver disease. The main risk factors for its development are poor nutrition, sedentary lifestyle and obesity. MAFLD is associated with various cardiometabolic conditions – lipid metabolism disorders, cardiovascular pathology and carbohydrate metabolism disorders. The association of MAFLD and type 2 diabetes mellitus (DM) is common among patients, since these diseases have a common pathogenesis link – insulin resistance. The combination of these diseases has a mutual negative effect on each other and increases the risks of cardiovascular diseases, hospitalizations, as well as the risks of liver fibrosis progression. Therefore, the detection of MAFLD and its treatment in type 2 DM are extremely important to improve the patient’s prognosis. Diagnostics of MAFLD includes laboratory and instrumental research methods. The “gold standard” of diagnostics is considered to be liver biopsy, but due to the fact that this method is invasive, it is rarely used and only for differential diagnostics of MAFLD with other liver pathologies. The most accessible instrumental method for detecting liver steatosis is ultrasound. Treatment of MAFLD primarily involves lifestyle changes (rational nutrition with limitation of simple carbohydrates and animal fats, adequate physical activity) and weight loss. Also, hypoglycemic drugs used to treat type 2 diabetes (metformin, pioglitazone, glucagon-like peptide-1 agonists) can have a certain positive effect on MAFLD. Essential phospholipids, which have membrane-stabilizing, antioxidant and antifibrotic effects, are also an important component of MAFLD treatment. A number of domestic and foreign studies have shown the high efficiency of Essential Phospholipids both in relation to biochemical parameters in patients with a combination of type 2 diabetes and MAFLD, and in relation to ultrasound signs, improving the function and structure of the liver in MAFLD, as well as slowing the progression of liver fibrosis.

Directed acyclic graph helps to understand the causality of malnutrition in under-five children born small for gestational age

Directed acyclic graph helps to understand the causality of malnutrition in under-five children born small for gestational age

Social determinants of health associated with increased prevalence of childhood malnutrition in Africa

Social determinants of health associated with increased prevalence of childhood malnutrition in Africa

An evaluation of interventions within a Growth Through Nutrition project aimed at enhancing optimal nutrition and water, sanitation and hygiene (WASH) and nutrition practices among nutritionally most vulnerable households (MVHHs) in Ethiopia.

Despite a downward trend, Ethiopia still faces significant challenges with high rates of stunting and acute malnutrition in children. To tackle these issues, the Feed the Future Ethiopia Growth Through Nutrition Activity, a USAID-funded project aligned with Ethiopia's National Nutrition Program, was executed from 2016 to 2023. This initiative aimed to enhance nutrition for women and young children across six regions through multisectoral interventions. Annual surveys conducted in 2017, 2018, and 2020 evaluated the impact of livelihood support and Water, Sanitation, and Hygiene (WASH)-focused social behavior change communication (SBCC) on vulnerable households with children under two. The results showed significant improvements in child nutrition. Dietary diversity among children increased from 12% to 34% (p<0.001), and the percentage of children receiving a minimal acceptable diet rose from 12% to 30.7% (p<0.001). Women's dietary diversity also improved markedly, from 2% to 16% (p<0.001). Handwashing practices saw improvements, with the proportion of households having handwashing facilities rising from 14% to 31% (p<0.001), and the adherence to critical handwashing moments increased from 16% to 23%. However, challenges in water treatment and latrine use persisted, with less than 25% improvement. The findings suggest that integrating livelihood support with SBCC interventions can positively enhance nutritional outcomes. Continued focus on these strategies is recommended to further support vulnerable households.

Study of Severe Acute Malnutrition in Children Aged 0-59 Months Hospitalized in the Pediatric Department of Sikasso Hospital

Introduction: Malnutrition is a backdrop on which several infections are grafted. The implementation of WHO guidelines would significantly reduce hospital mortality due to severe malnutrition. General Objective: To evaluate the epidemio-clinical characteristics of severe acute malnutrition in children aged 0 to 59 months in the pediatric department of Sikasso hospital from 2015 to 2019. Methodology: The study was conducted in the pediatric department of Sikasso hospital. It was a cross-sectional study with retrospective data collection from January 2015 to December 2018 and prospective from January 2019 to December 2019, children aged 0 to 59 months hospitalized with a P/T ratio &lt; -3 z score or a MUAC &lt; 115mm or nutritional edema. Results: During the study period we had 11,255 cases of hospitalization including 190 cases of severe acute malnutrition in children aged 0 to 59 months, i.e. a frequency of 1.68%. The average age was 19 months with extremes ranging from 6 months to 48 months. The male sex dominated with 56% of cases with a sex ratio of 1.27. The unfavorable socio-economic conditions in the families were 66.32%. The most frequent reasons for consultations were fever and anorexia, respectively 75.79% and 65.26%. Fever was the most common complication, 76% of cases, followed by anemia and anorexia, respectively 65% and 63%. Malaria was the most associated pathology, 47.43%, followed by cases of gastroenteritis and pneumonia, respectively 20.57% and 17.71%. According to the outcome, 8% of malnourished people died.

MALNUTRITION AND COGNITIVE DEVELOPMENTAMONG UNDER FIVE YEARS CHILDREN IN INDIA

Malnutrition is a silent epidemic that is associated with structural and functional brain disease. Malnourished children have been found to have a wide range of cognitive abnormalities.Malnutrition in under five yearschildren has been linked to lower intelligence quotient, cognitive development, academic achievement, and behavioural difficulties in school-aged children compared to matched controls.The aim of this review is to give a comprehensive overview of the current knowledge on the link between malnutrition and cognitive development. A study was conducted by the secondary data including review paper, research articles, WHO report, newspaper articles and NFHS-5 report in the literature that have attempted the existing knowledge on the study. This article discusses the most important malnourished factors and its associations with cognitive functions.

Utilization of biscuits as nutritional intervention to reduce stunting among children: A systematic review

Childhood stunting remains a global health issue with significant consequences for the growth, long-term health, and development of childre, Poor nutrition is a well-established contributor to childhood stunting. This study aims to investigate the potential of utilizing biscuits as a nutritional intervention to improve the child‘s stunting condition. This systematic review was consisted of a literature search in several databases: Scopus, Web of Science, ScienceDirect, PubMed, and Springer, following the PRISMA methodology. Our search yielded a total of 836 records, while 11 studies were finally included after the screening. The studies revealed critical findings regarding the utilization of biscuits as a carrier in providing essential nutrients. Nevertheless, more well-designed and standardized studies are required to establish clear guidelines for the formulation and implementation of biscuit-based interventions. Policymakers and health practitioners should consider incorporating fortified biscuits into strategies aimed at reducing stunting, especially in regions with a high prevalence of stunting.

Comparison of the efficacy and safety of neoadjuvant PD-1 inhibitors plus chemotherapy vs targeted therapy plus chemotherapy in locally advanced hypopharyngeal squamous cell carcinoma.

To investigate the clinical efficacy, preservation of laryngeal function, and safety differences between PD-1 inhibitors combined with chemotherapy, and targeted therapy combined with chemotherapy in LA HPSCC patients. This was a retrospective analysis of patients with LA HPSCC treated at Beijing Tongren Hospital, Capital Medical University from October, 2020 to March, 2024. A total of 110 eligible patients were included, 56 in the PD-1 inhibitors combined with chemotherapy group (Group A), and 54 in the targeted therapy combined with chemotherapy group (Group B). Relevant clinical data were collected, and the clinical efficacy, preservation of laryngeal function, complete response (CR) rate, pathological complete response (pCR) rate, major pathological response (MPR), and treatment-related adverse events (TRAEs) of the two groups were analyzed and compared. In both groups A and B, the objective response rate (ORR) and disease control rate (DCR) were similar with no significant differences, but the pCR rate in Group A was much higher than that in Group B, at 37.5% and 7.4%, respectively (p<0.001). The rate of primary tumor downstaging in group A was much higher than that in group B (76.8% vs. 38.9%) as well (p<0.0001). In addition, the 1y-OS rate in group A was 95.7%, compared to 87.0% in group B (p=0.106, HR=0.34; 95% CI: 0.114-1.013), and the 1y-PFS rate was 89.4% in group A compared to 85.2% in group B (p=0.399, HR=0.675; 95% CI: 0.275-1.659). Furthermore, the larynx function preservation rate was significantly higher in group A at 85.7%, compared to that of group B at only 66.7% (p=0.019). There were no deaths due to TRAEs in either group, and there was no significant difference in the incidence of grade 3-4 TRAEs between the two groups either (p=0.77). The main TRAEs in Group A were metabolism and nutrition disorders (52/56, 92.9%) and, in Group B were blood and lymphatic system disorders (40/54, 74.1%). PD-1 inhibitors combined with chemotherapy showed better short-term efficacy compared to targeted therapy. Additionally, a trend toward improved long-term survival was observed with PD-1 inhibitors but not with targeted therapy. Results for both groups indicate that neoadjuvant therapy is both safe and manageable.

Longitudinal trajectories of the overall and regional body composition between severe acute malnourished and well-nourished children of Rohingya refugee camps.

The present study aimed to observe how body composition differs between severe acute malnutrition (SAM) (treated with ready-to-use therapeutic food, RUTF) and well-nourished children. A longitudinal investigation was conducted among well-nourished and SAM children of 6-59 months in Rohingya refugee camps. These two groups (350 children in each group) of children were observed over 12 weeks and individual data were collected during admission, follow-up visits, and at the time of discharge. Anthropometric information was collected following standard procedures. The thicknesses of the biceps, triceps, subscapular, and supra iliac skinfolds were measured using a Herpenden-type skinfold caliper. Separate linear mixed models were conducted to assess associations of the independent variables (i.e., group and time) with each of the dependent variables (i.e., biceps, triceps, subscapular, supra-iliac skinfold thickness (ST), fat mass (FM), and fat-free mass (FFM)). Both in well-nourished and SAM children, the mean biceps, triceps, subscapular, and supra-iliac ST, FM, and FFM increased over the 12 weeks. The increase in biceps ST was significantly faster in the SAM children compared to the well-nourished children (difference in slope = 0.366 mm every four weeks; p < 0.001). The increment rate in triceps ST was also faster in the SAM children compared to the well-nourished children (difference in slope = 0.430 mm every four weeks; p < 0.001). Moreover, the pace of increase in subscapular (difference in slope = 0.027 mm every four weeks; p < 0.001), and supra-iliac (difference in slope = 0.211 mm every four weeks, p < 0.001) ST was also significantly higher in the SAM group. Similarly, the change in FM (difference in slope = 0.065 kg every four weeks, p < 0.001) and FFM (difference in slope = 0.152 kg every four weeks, p = 0.023) was also significantly faster in SAM children compared to the well-nourished children over the treatment period. Furthermore, the girls gained significantly higher triceps ST, subscapular ST, FM, and FFM compared to the boys. The benefit of RUTF was evident from this longitudinal study in the recovery of FM and FFM contents among the SAM children of Rohingya refugee camps.

HPV Vaccines

Human papillomavirus (HPV) is a double-stranded DNA virus and a source of infection that primarily affects the skin and mucous membranes. It can be transmitted through sexual contact and contaminated surfaces. There are over 200 genotypes of HPV, approximately 40 of which infect the anogenital region. High-risk HPV types, such as HPV-16 and HPV-18, can lead to the development of various cancers, particularly cervical cancer. Factors that increase the risk of transmission include having multiple sexual partners, early initiation of sexual activity, and having an uncircumcised male partner. Low socioeconomic status, poor nutrition, immunosuppression, and co-infections with HIV, genital herpes, or chlamydia can result in persistent and severe HPV infection. Three types of vaccines have been developed against HPV: bivalent, quadrivalent, and nonavalent vaccines. The bivalent vaccine provides protection against HPV-16 and HPV-18; the quadrivalent vaccine is effective against HPV-16, HPV-18, as well as HPV-6 and HPV-11. The nonavalent vaccine offers the broadest protection, covering nine different types of HPV. All vaccines are approved for males and females aged 9 and older. Vaccination before the onset of sexual activity significantly increases protection against cervical cancer.

Poor nutrition doubles post-COVID-19 syndrome risk in cancer patients: insights from a Chinese multicentre study

BackgroundSince 2019, approximately 760 million SARS-CoV-2 cases have been reported globally, with post-COVID-19 syndrome posing significant challenges for cancer patients due to their immunosuppressed status and poor nutritional conditions. The role of nutritional status in influencing their infection risk and post-COVID-19 outcomes remains unclear, underscoring the need for targeted research and strategies.ObjectiveTo investigate the impact of baseline nutritional status on SARS-CoV-2 infection and the risk of post-COVID-19 syndrome in cancer patients.MethodsA multicenter cross-sectional study was conducted from December 2022 to June 2023 in four tertiary hospitals across China. Cancer inpatients aged 18 years and older were enrolled and classified into two groups based on their Nutritional Risk Screening (NRS) scores. The correlation between SARS-CoV-2 infection, post-COVID-19 syndrome and nutritional status were analyzed using multivariable logistic regression.ResultsAmong 834 eligible cancer patients, 10.8% were in the high nutritional risk group (NRS ≥ 3). The prevalence of SARS-CoV-2 infection was 58.8% (95% confidence interval, CI: 56.8–60.8%), and post-COVID-19 syndrome was 21.0% (95% CI: 10.4–14.4%). After adjusting for confounding factors, the high nutritional risk group had a significantly higher prevalence of post-COVID-19 syndrome compared to the low nutritional risk group (32.7% vs. 19.5%, AOR: 2.37, 95% CI: 1.23–4.54, p = 0.010). However, no significant difference in SARS-CoV-2 infection rates was found between the two groups (61.1% vs. 58.5%, AOR: 1.12, 95% CI: 0.70–1.80; p = 0.634).InterpretationPoor baseline nutritional status in cancer patients is associated with a higher prevalence of post-COVID-19 syndrome, providing preliminary information on post-COVID-19 syndrome in this population. These findings underscore the importance of adequate nutritional management in cancer patients, particularly during pandemic recurrences.

Study on Weight Gain Efforts through Indigenous Technical Knowledge

Introduction: In India, under-five child malnutrition is a serious public health issue. This is demonstrated by the fact that India has one of the highest rates of underweight children worldwide. Aims: The study was carried out to assess the spatial distribution of nutritional status of children of 1-5 years through weight-for-age, height-for-age, weight-for-height data collected by the KVK. Preschoolers' dietary health was regressed on several sociodemographic factors after eliminating the effect of age. The information reveals that children's nutritional condition varies geographically and by gender in India. Methodology: A study was conducted in district Seoni of Madhya Pradesh to eliminate malnutrition via using indigenous technical knowledge (ITK). The trials were conducted in three following years viz 2020 to 2023. Primarily the training was conducted of mothers along with Anganwadi workers regarding the addition of sweet rice to kids from 1-5 years age group. Results: There was twice-daily portions of sweet rice, was prepared by using Jaggery by adding water, desi ghee, and roasted rice dry fruits added to it and then it cooked for 15-30 min and given for 45 days. The average body weight gain after evaluation and personal conversations of mothers was recorded as 9.91 kg and the proportion change against farmers practice was 13.48. Conclusion: The study concluded that rice prevalent areas and rice-based food habits for mothers and children should be adopted the sweet rice (ITK) the recommended practice against farmers’ practice.

Assessment of nutritional, anti-nutritional and functional properties of marketed biofortified sweet potato cultivars

Sweet potatoes, a nutrient-dense crop are recognized as a potential functional food to mitigate an array of nutritional disorders. In India, sweet potato is considered a secondary staple crop due to its unique nutritional properties. Owing to its high consumption, food interventions like biofortification have been made to enrich the essential bioactive compounds (carotenoids and anthocyanins). The current study highlighted the nutritional, anti-nutritional and mineral analysis of farmer-grown biofortified sweet potatoes i.e., Bhusona and Bhu-Krishna varieties and compares them with officially available data. High antioxidant activity was observed in Bhu-Krishna with 40 mg followed by Bhu-Sona and white flesh (unfortified variety) (19.3 and 18.7 mg/100 g dry basis). The total carotenoid content ranged from 0.9 to 12.6 mg/100 g dry weight, with the highest content in BhuSona. The anti-nutritional content like phytates and tannins in sweet potato cultivars ranged between 57.35 and 60.82%. However, the antinutrient content was comparatively high in selected biofortified varieties, establishing research prospects concerning human health. These results provide insights into the suitability of biofortified varieties for inclusion in diets that are nutritionally adequate and have sufficient nutritional information for policymakers to promote these varieties to the vulnerable.

Distribution and redistribution of salt ions in saline soils with shallow groundwater table

Saline water resources are more abundant than freshwater. Bringing these resources into sustainable, productive use will offer opportunities to reduce competition for freshwater resources, especially in arid and semi-arid areas where freshwater is scarce. Hence, the primary objective of this study was to elucidate the dynamics of salt ions in saline profiles of various soil types (sandy Clovelly and sandy loam Bainsvlei) under malt barley cultivation across 2 seasons where no leaching between the seasons took place. Results of this lysimeter study investigating increasing irrigation salinity (ECi) set at 1.5, 4.5, 6, 9, and 12 dSꞏm−1 over 2 seasons were used to explore ion dynamics of a saline environment. The lysimeter set-up included a saline constant (1.2 m) groundwater table with its salinity corresponding to ECi. Findings showed that ion concentrations are higher closer to the water source only in the Bainsvlei soil and remain variable in the Clovelly soil. Salt dynamics were more predictable in sandy loam soil than in sandy soil, making management of saline sandy soils far more challenging when leaching is not possible. Therefore, our hypothesis that the absence of leaching between seasons will lead to a differentiated progressive accumulation of salt ions in the soil profile, with variable effects on the soil depending on soil texture, was true. We conclude that the desalinized zone, which we determined to be at a depth of 600 mm, should be used to guide crop selection. Furthermore, in addition to the apparent provision for leaching of saline profiles, fertilization should target restoring ion balances, especially provisioning for calcium deficiencies. Both soils were prone to nutritional disorders, most especially calcium deficiency. Therefore, in addition to provision for leaching saline profiles, fertilization should target calcium provisioning for crop production in arid saline environments.

Examining the complex dynamics influencing acute malnutrition in Turkana and Samburu counties: Study protocol.

Acute malnutrition in children under 5 years is persistent in Eastern Africa's arid and semiarid lands. This study aimed to identify the drivers of acute malnutrition in Turkana and Samburu counties, Kenya. This was a population-based longitudinal mixed-methods observational study. Qualitative and quantitative data were collected at Wave 1, but only quantitative data were collected during follow-up. Participants were a representative sample of children and their primary caregivers from households with children under 3 years at Wave 1. Anthropometric measurements of all children under 5 years in the sampled households were taken at Wave 1 (May to July 2021), and one child under 3 years was randomly selected for follow-up about every 4 months over 2 years for six data collection waves. The study also collected data on sociodemographics; child feeding practices and morbidity; household water and food insecurity; shocks; coping strategies, social safety nets and economic safeguards; water, sanitation and hygiene; women's decision-making and food consumption. Qualitative data were collected through community dialogues, focus group discussions, in-depth interviews, photovoice and key informant interviews with mothers and fathers with children under 5 years, community leaders, county officials and staff of nongovernmental organisations. Data collection is complete and analysis is ongoing. The analysis includes thematic analysis of qualitative data and descriptive and multi-variable regression analyses of quantitative data.

Relationship Between Gross Motor Function and Nutritional Status of Children with Cerebral Palsy-A cross-sectional study in a Tertiary Care Hospital of Bangladesh

Background: Cerebral Palsy (CP) is one of the most common causes of chronic disability in children. Childhood malnutrition is a major public health issue in low- and middle-income countries. The gross motor function of children with CP can easily be assessed by the tool Gross Motor Function Classification System- Expanded &amp;Revised (GMFCS-E&amp;R). This study aimed to determine the relationship between GMFCS and nutritional status in children with cerebral palsy. Method: This cross-sectional observational study was conducted in the Department of Pediatric Neurology, IPNA, BSMMU from October 2019 to August 2020. All the patients aged 2-12 years were diagnosed as CP by clinical criteria and classified by GMFCS. Nutritional status (weight for age, height for age, weight for height, BMI) is assessed and classified according to the World Health Organization growth charts. Then linear and multinomial logistic regression methods to determine the associations between GMFCS and nutritional status. The correlation between motor function and nutritional status was assessed. Results: Among the 50 children 68% were male and 32% were female. The mean age of the CP children was 4.90±3.05 years. Most patients (66.0%) came from poor families followed by 24% from the middle class. Functionally majority of patients were in GMFCS level IV (28.0% ) and level V (20.0%). Maximum patients in spastic quadriplegia 42%, spastic hemiplegia 16%. The level of GMFCS was associated with nutritional status, as determined by anthropometry. Moderate and severe underweight significantly related with GMFC level IV and V. Moderate and severe stunted was significantly related with IV and V GMFC level. Moderate wasted was significantly related to GMFC levels III and IV. Mild malnutrition was significantly with GMFC level II and III. Severe malnutrition is significantly related to GMFC level IV and V. Conclusion: This study showed majority of cerebral palsy cases had severe functional gross motor disability and also severe grade of malnutrition. A significant association between severe grade of malnutrition and severe grade of motor disability was found. J Bangladesh Coll Phys Surg 2024; 42: 342-349

Malnutrition in infants aged 6-23 months in China’s poorest rural counties from 2016 to 2021: cross sectional study

ObjectivesTo assess trends and differences in child malnutrition by population subgroups among infants aged 6-23 months in China’s poorest rural counties.DesignSix consecutive cross sectional surveys were conducted annually.SettingThe study was...