Objectives: The purpose of this study was to identify the effect of pre-basic nursing science program on academic resilience, learning agility and learning attitude in first-year nursing students. Methods: This study was a non-equivalent control group pretest-posttest quasi-experimental design. There were a total of 56 participants, consisting of 28 nursing students in the experimental group and 28 nursing students in the control group. Academic resilience, learning agility and learning attitude between the experimental and control groups were measured before and after the program participation. Data were collected from October 13 to November 10, 2023 by taking a self reported survey and analyzed by using chi-square test, Fisher’s exact test, independent t-test, and paired t-test with SPSS 25.0 program. Results: Homogeneity between the two groups was ensured before the program. After the program compared to before the program, there were no statistical differences in academic resilience (t=0.09, <i>p</i>=0.925), learning agility (t=0.91, <i>p</i>=0.366), and learning attitude (t=0.26, <i>p</i>=0.798) between two groups. On the other hand, the academic resilience (t=4.15, <i>p</i><0.001), learning agility (t=4.34, <i>p</i><0.001), and learning attitude (t=4.37, <i>p</i><0.001) of the experimental group increased statistically significantly. Conclusions: According to these results, pre-basic nursing science program could be used to increase academic resilience, learning agility and learning attitude of first-year nursing students. In the future, more research is needed on the development of various basic science program for first-year nursing students.
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