A numerical parametric study on the burner arrangement design for a steam methane reforming reactor was conducted under three burner configurations: a single co-axial inside burner (SCIB), a single top burner (STB), and multiple top burners (MTB). The burner combustion gas inlet angle was changed to 25°, 45°, and 90° with respect to the horizontal plane. Moreover, the number of reformer tubes inside the reactor was changed to four, six, and eight tubes arrangements. Furthermore, the models were numerically evaluated for temperature distribution inside the combustion space and hydrogen mole fraction in the reactor by incorporating the Xu and Forment model using a user-defined function (UDF). The results show that the STB configuration is preferable over the SCIB and MTB configuration due to the uniform temperature distribution inside the combustion space and efficient heating from the combustion gas. Furthermore, the standard deviation of the temperature inside the combustion space was found to be lower for the STB arrangement. Moreover, the STB configuration reported a maximum temperature uniformity index of 0.92 for the eight-tubes reformer arrangement. The value of the average wall heat transfer coefficient and wall heat flux at the reformer tube surface for STB configuration was 396.6 W/(m2K) and 21.7 W/m2, respectively. The velocity inlet angle of the burner combustion gas also plays an important role in the methane steam reforming reaction. A burner combustion gas inlet angle of 45° was observed to have better hydrogen conversion than the 25° and 90° inlet angles due to the proper mixing, leading to more effective heat transfer to the reformer tubes.