As a generalization of matching preclusion number of a graph, we provide the (strong) integer $k$-matching preclusion number, abbreviated as $MP^{k}$ number ($SMP^{k}$ number), which is the minimum number of edges (vertices and edges) whose deletion results in a graph that has neither perfect integer $k$-matching nor almost perfect integer $k$-matching. In this paper, we obtain a necessary condition of graphs with an almost-perfect integer $k$-matching and a relational expression between the matching number and the integer $k$-matching number of bipartite graphs. And then the $MP^{k}$ number and the $SMP^{k}$ number of complete graphs, bipartite graphs and arrangement graphs are obtained, respectively.