A field experiment was conducted on a clayey soil during twosuccessive winter seasons of 2007-2008 and 2008-2009 at Damas village, MitGhamer district, El Dakahlia Governorate, Egypt to evaluate the effectivenessof seed inoculation with rhizobium and foliar spray with zinc and cobalt onfaba bean (Vicia faba L.) yield and its components as well as seed protein andnutrient contents. Zinc and cobalt sulphates were applied at three rates of 0,250 and 500 mg L-1 for Zn and 0, 15 and 25 mg L-1 for Co. Yield and itscomponents (i.e., number of tillers plant-1), number & dry weight of nodulesand nitrogenase activity of root nodules plant-1 at two investigated periods of45 and 70 days from sowing as well as number of pods plant-1, grain contentsof protein and elements (i.e., N, P, K, Fe, Zn, Cu & Co). Soil content ofavailable nitrogen forms (NH4+ and NO3-) after 70 days from sowing and atharvest were taken into consideration in this study.The obtained data show that seed inoculation with rhizobiuminoculation and foliar spray with Zn and Co led to a significantly increased ineach of tiller plant-1, number of pods plant-1, grain protein, grain and strawyields in kg fed-1. A parallel trend was occurred for the positive effect of theapplied treatments on faba bean grain contents of N, K, Fe, Zn, Cu and Co,however, the greatest values were achieved at the highest rates of 500 and 25mg L-1 of Zn and Co, respectively. On the other hand, no changes wereobserved for grain content of P by increasing the applied Zn and Co rates,may be due to the antagonism between Zn and P.As for the beneficial effects of the applied treatments on the availablenitrogen content in the experimental soil, data show that seed rhizobiuminoculation as well as Zn and Co as foliar application resulted in a noticeableincrease for available content of nitrogen forms (NH4+ and NO3-) at bothinvestigated periods of 70 days after sowing and at harvest as compared to thecontrol treatment. At the same times, it is noticed that the available N-formsgave the greatest values at 70 days after sowing as well as in case of Znfoliarly as compared to at harvest and case of Co. This was true, since suchincrease was more closely to the nitrogenase activity. It is noteworthy tomention that seed inoculation and Zn or Co foliar application showed aparallel trend for the pronounced increases of all tested plant and soilparameters as compared to the control treatment under both studied growingseason conditions. So, it could be said that the residual effect of N-biofixation in the soil after harvest leading to rationalize use of N-mineralfertilizers for the next crop, which is surplus point for sustainable agriculturesystem.