Abstract Aim The Scoliosis Research Society Health-Related Quality of Life Questionnaire (SRS22) allows clinicians insights into the challenges patients with scoliosis face. This study aims to assess compliance with SRS22 questionnaires, identifying key factors impacting adherence. Method This retrospective cohort study of the British Spine Registry included 216 patients who underwent surgery for Adolescent Idiopathic Scoliosis between 2018 and 2022 at a single institution. Completed SRS22s at 5 timepoints were collected with contact and deprivation data. Results SRS22 completion averaged 44.0% across time points. Contact information was available in 84.1%. There was a significant drop in completion from 2018 (60.4%) to 2021 (30.6%) at follow up. Binary logistic regression demonstrated preoperative and 6-week SRS22s were significant predictors of completed 6-month and 1-year questionnaires (OR: 2.46; p = 0.037, OR: 3.31; p = 0.0041). Six-month completion and telephone numbers were significant predictors of 1-year completion (OR: 6.29; p < 0.001, OR: 5.55, p = 0.048). One year completion was the only significant predictor for 2-year completion (OR: 10.29; p < 0.001). Index of multiple deprivation was not significant to SRS22 completion. Conclusions With lowering rates of engagement, input at the beginning of care may provide an effective strategy to maximise long-term collection. With incomplete preliminary questionnaires, later questionnaire completion is unlikely. Long term completion does not seem to directly correspond to email availability or area deprivation. Clinical initiative and funding, maximising completion at early patient visits, could lead to significantly greater engagement.