Number Of HIV Cases Research Articles

Prevention Risk Behavior of HIV/AIDS in Senior High School Student

World Health Organization (WHO) data are 680.000 people died by HIV in 2020. Based on data, 99.000 are chidren under 15 years ages and 580.000 are adults over 15 years. The number of HIV case in Gowa district from years 2021 to on November 2023 grow up. In years 2021 number of HIV cases are 55 peoples. In years 2022 number os HIV cases are 72 peoples. Number of HIV cases in years 2023 until on November is found the number is 136 peoples. The aim of this research is to analyze the prevention of HIV/AIDS risk behavior among students at SMA Senior 1 Gowa.. Quantitative research. The number of sample are 194 respondents by purposive sampling. Data source from sekunder data in 2024. The results of analysis described gender toward risky behavior (p value 0.290). economy status toward risky behavior (p value 0.316). attitude toward risky behavior (p value 0.092). cultural toward risky behavior (p value 0.081). media toward risky behavior (p value 0.000). obedience religious toward risky behavior (p value 0.000). knowledge towar risky behavior (p value 0.000). Conclussion, on no effectedon gender, economy status, attitude, and culture. Nonetheless, effected on media, obedience religious and knowledge.

Health service quality of human immunodeficiency virus voluntaries’ counselling and testing

United Nations & AIDS (UNAIDS) in 2019 stated that 38 million individuals in the world were suffering from human immunodeficiency virus or HIV. Since it was discovered in 1987, the number of HIV cases in Indonesia until mid-2020 was 436,948 cases, of which 64,990 people have died. This study aims to assess the quality of health services with the service quality (SERVQUAL) analysis model on voluntary HIV counseling and testing. A quantitative study was conducted with a descriptive observational analytic approach and a cross-sectional design on 120 respondents. The variables were measured using a service quality questionnaire and Likert scale. The results showed a difference between the expectations and perceptions of respondents on the service quality of voluntary HIV counseling and testing. The statistical analysis (p=0.000) shows that the health services for voluntary HIV counseling and testing have poor quality. However, the respondents gave good scores on responsiveness and assurance of the services. Managers and relevant authorities need to plan and pay special attention to other yet optimal variables.

Cost of implementing HIV pre-exposure prophylaxis at community-based clinics in Indonesia.

Currently, Indonesia still has one of the highest rates of new HIV/AIDS infections among countries in Asia and the Pacific region. The WHO has recommended pre-exposure prophylaxis (PrEP) as an additional HIV epidemic prevention step, which has been applied globally and related to the reduction in the number of HIV cases. However, information on the cost of implementing PrEP is rarely available in developing countries, especially in Southeast Asia. Designing a cost-effective approach to scale up PrEP and to estimate the potential budget impact requires information on the cost of implementing PrEP. This study aims to estimate the cost of implementing PrEP at community-based clinics in Indonesia. We collected healthcare and non-healthcare/client costs from nine community-based clinics in various cities/districts in Indonesia. The healthcare costs included data on resource utilisation and costs to deliver PrEP, divided into recurrent and capital costs using a discount rate of 3%. Non-healthcare costs included out-of-pocket costs (e.g., transportation, meals) and productivity loss by clients and accompanying person(s) in accessing PrEP. On average, we interviewed 27 clients/clinic. The annual cost of providing PrEP per client is US $365.03, 39% lower than the yearly cost of antiretroviral treatment (ART) per person (approximately US $600). Drugs and non-healthcare costs contribute approximately 67% of the cost. The cost of PrEP amounts to US $292,756.45/year, covering 802 clients. The non-healthcare cost per visit at all sites never reaches more than 10% of the average monthly household expenditure. The cost of providing PrEP per person is approximately US $365 and is 39% lower than the annual cost of ART per person. Lowering the cost of PrEP ARV drugs would reduce the cost. Scaling up PrEP should recognise this cost structure and strive to reach economies of scale as the intervention gains more clients while simultaneously controlling new HIV infections.

APPLICATION OF PANELIZED SPLINE-SPATIAL AUTOREGRESSIVE MODEL TO HIV CASE DATA IN INDONESIA

Spatial regression analysis is a statistical method used to perform modeling by considering spatial effects. Spatial models generally use a parametric approach by assuming a linear relationship between explanatory and response variables. The nonparametric regression method is better suited for data with a nonlinear connection because it does not need linear assumptions. One of the nonparametric regression methods is penalized spline regression (P-Spline). The P-spline has a simple mathematical relationship with mixed linear model. The use of a mixed linear model allows the P-Spline to be combined with other statistical models. PS-SAR is a combination of the P-Spline and the SAR spatial model so that it can analyze spatial data with a semiparametric approach. Based on data from monitoring the development of the HIV situation in 2018, the number of HIV cases in Indonesia shows a clustered pattern that indicate spatial dependence. In addition, the relationship between the number of positive cases and the factors tends to be nonlinear. Therefore, this study aims to apply the PS-SAR model to HIV case data in Indonesia. The resulting model is evaluated based on the estimates of autoregressive spatial coefficient, MSE, MAPE, and Pseudo R2. Based on the results, the PS-SAR model has an autoregressive spatial coefficient similar to the SAR model and has smaller MSE and MAPE than the SAR model.

Cost-effectiveness prediction of AIDS interventions among men who have sex with men in Ningbo

Objective: To provide information reference for resource allocation and decision-making in related fields, the cost-effectiveness of HIV input among men who have sex with men (MSM) in Ningbo. Different intervention coverages were compared. Methods: Taking MSM as the target population, data were collected and modeled by Optima HIV for the corresponding HIV health output and the budget under different intervention coverages. Results: According to the estimated size of the MSM population, which was 19 584 in Ningbo in 2020, if the coverage of 2020 baseline intervention is maintained in the next ten years, the number of HIV cases, new HIV infections, and HIV-related deaths among this population will show an upward trend. It is estimated that from 2021 to 2030, 7.9% of new infections and 1.7% of deaths can be avoided and the relevant funding investment comed to 2.4 time the baseline if the intervention coverage rate expanded to 3.0 times the 2020 baseline. After the coverage rate of intervention expanded to 3 times the baseline, it continued to grow, the health effect did not increase. Conclusions: At present, expanding the baseline coverage of HIV-related intervention projects among MSM in Ningbo and increasing capital investment will still reverse HIV-related death and reduce new infections. Moreover, there is a saturation point of the intervention effect. Researchers and policymakers must explore more effective interventions/combinations to obtain more significant health outcomes.

Approaches to forecasting of time dynamics of the processes and use of Farr’s epidemic evolution law on example of dynamics of new cases of HIV-infection in Russian Federation

Introduction. Forecasting of different processes in health, including epidemics, are important area of public health. There exists an idea that in some cases simple models can give adequate forecasts.Goal of this study was to evaluate possible use and results of forecasting of registration of new cases of HIV infection in Russian Federation based on well-known Farr’s law.Materials and methods. The official statistical data on new HIV cases in 1999–2020 in Russian Federation were used. Parameters for forecasting new cases until 2027 were calculated according to Bregman and Langmuir. For evaluation of forecasting the calculations were done for 2015–2020 after fitting model with data until 2014. Normal components of the empirical epidemic curve were estimated and more appropriately fitted distributions were found for the data described by those components.Results. Estimations according to the Farr’s law somewhat undercount number of the new cases of HIV infection (it forecast 99% (95% CI 92–106%) cases when smoothing was used and 97% (95% CI 89–106%) when raw data were used). In general, especially when smoothing was used, fit was satisfactory. Forecast until 2027 show that total number of HIV cases in 1999–2027 will be 1.7–2.0 mln people. Analysis of most probable distribution of the second peak of epidemic curve show that it is lognormal, which allow for much larger number of infected in medium- and long-term perspective.Conclusion. Though Farr’s law could be used for short-term forecast it is not recommended to weaken preventive programs due to possibility of large increase in number of HIV-infected in comparison with Farr’s law forecast.

Prevention of mother-to-child HIV transmission: from the first stages to the possibility of elimination

Despite the success in reducing mother-to-child HIV transmission rate worldwide, the problem of perinatal HIV transmission is still relevant. Sexual activity nowadays is the predominant way of transmission, therefore the number of HIV cases among women growths. This leads to an increased number of pregnancies and childbirth in HIV-infected women. Better preventive treatment has decreased the transmission risk to 1% or less. Despite this, the Russian Federation is still not among the countries where the elimination of mother-to-child transmission has been recorded. This review article focuses on the main stages of mother-to-child transmission prevention from the time that no antiretroviral therapy was available to the current stage, when highly active antiretroviral therapy is used during pregnancy, childbirth and for the treatment of newborns. The research provides a comparative analysis of modern national and international clinical recommendations for the prevention of mother-to-child HIV transmission.

Characteristics of HIV-1 molecular transmission networks and drug resistance among men who have sex with men in Tianjin, China (2014\u20132018)

BackgroundIn Tianjin, China, there is a relatively high prevalence of HIV in men who have sex with men (MSM). The number of HIV cases in Tianjin is also increasing. We investigated the HIV molecular transmission network, genetic tropisms, and drug resistance mutations in Tianjin.MethodsBlood samples were collected from 510 newly diagnosed antiretroviral therapy (ART)-naïve HIV-1-infected subjects among MSM in Tianjin. Partial pol and env genes were sequenced and used for phylogenetic, genetic tropism, and genotypic drug resistance analyses. Molecular clusters were identified with 1.5% genetic distance and 90% bootstrap support.ResultsAmong the 436 HIV-1 pol sequences obtained from the study participants, various genotypes were identified, including CRF01_AE (56.9%), CRF07_BC (27.8%), B (7.3%), CRF55_01B (4.1%), unique recombinant forms (URFs) (3.7%), and CRF59_01B (0.2%). A higher prevalence of X4 viruses was observed in individuals infected with CRF55_01B (56.3%) and CRF01_AE (46.2%) than with other subtypes. Of all 110 sequences in the 36 clusters, 62 (56.4%) were observed in 23 CRF01_AE clusters and 18 (16.4%) in four CRF07_BC clusters. Eight sequences clustered with at least one other shared the same drug resistance mutation (DRM). In different cluster sizes, the distributions of individuals by age, presence of sexually transmitted disease, and presence of DRMs, were significantly different.ConclusionWe revealed the characteristics of HIV molecular transmission, tropism, and DRMs of ART-naïve HIV-infected individuals among the MSM population in Tianjin. Identifying infected persons at risk of transmission is necessary for proposing counseling and treating these patients to reduce the risk of HIV transmission.

Gambaran Minat Ibu Hamil dalam Mengikuti Program Preventation of Mother to Child Transmission (PMTCT) di Kelurahan Tanjung Uma Wilayah Kerja Puskesmas Lubuk Baja

Penyebaran HIV dan AIDS di Indonesia dari tahun ke tahun menunjukan peningkatan yang cepat. Jumlah kasus HIV sampai dengan mei 2017 sebanyak 103.759 dan AIDS sebanyak 43.347, dengan kematian sebanyak 8.340. dengan peningkatan kasus yang sangat besar tersebut maka WHO mengingatkan Indonesia sebagai salah satu negara Asia tercepat dalam hal peningkatan populasi HIV dan AIDS. (Kemenkes RI, 2015). Ibu hamil merupakan kelompok beresiko tertular HIV yang berdampak pada bayi yang dikandungnya seiring dengan meningkatnya jumlah laki-laki yang melakukan hubungan seksual tidak aman atau beresiko, yang selanjutnya akan menularkan pada pasangannya (istrinya)Dari data yang didapat dari 5.138 ibu hamil yang konseling dan test HIV, ada 32 yang positif HIV dan 15 AIDS, serta ada 19 bayi yang lahir dari ibu dengan HIV positif. Secara keseluruhan, penderita HIV di Kota Batam tahun 2017 mencapai 1038. Tujuan dari penelitian ini adalah untuk mengetahui minat ibu hamil dalam memanfaatkan program PMTCT. Jenis penelitian adalah penelitian survey yang bersifat analitik dengan pendekatan cross sectional. Besar sampel yaitu 100 ibu hamil di Wilayah Kerja Puskesmas Lubuk Baja. Alat pengumpulan data dengan kuesioner. Dari penelitian didapatkan minat ibu hamil dalam mengikuti program Prevention of Mother to Child Transmission (PMTCT) sebagian besar berada pada kategori berminat sebanyak 70 ibu hamil (70%) sedangkan tidak berminat 30 ibu hamil (30%). Untuk mengatasi masalah ini diharapkan kepada tenaga kesehatan untuk memberikan informasi ataupun penyuluhan tentang pemanfaatan PMTCT kepada Ibu hamil.

Situation of PMTCT in Bhutan, 14 Years’ Experience

Introduction: Prevention of mother-to-child transmission activities form important part of HIV/AIDS prevention program of any community or country. Methods: Information from the PMTCT Programme from the Ministry of Health and other published literature on HIV in Bhutan were reviewed. Results: The first case of mother to child transmission was reported in Bhutan in 2001. However, the retrospective study shows that one of the earliest mothers-to- child transmissions could have taken place back in 1997. Strategies for the prevention of mother-to-child transmission (PMTCT) of HIV in Bhutan have endured substantial advancement based on global scientific evidence. It is a concern as there is a slow rise in the number of HIV cases. The main modeof transmission is unsafe heterosexual practice in Bhutan. Before the planned PMTCT program, 3 children were infected. After launch of proper PMTCT program, we had all the components of effective strategies in PMCT program which have evolved with better ones with time. Due to this, MTCT was 3.2%. With undetected HIV infections, 32 children were born outside of the program and actual national MTCT rate is 5.5%. Conclusion: There is increasing number of people every year with new HIV infections. In addition, our detection gap is 45% with about 602 undiagnosed in the community. Every effort should be put forward to upscale the PMTCT program for Bhutan to eliminate Mother-to-Child transmission (MTCT) of HIV by 2020 and beyond.

Supporting Factors of Sex Workers Behavior on HIV/AIDS Prevention: A Qualitative Study

As of November 2018, the number of HIV cases in Semarang reached up to 546. Sex workers have the highest risk to contract HIV/AIDS due to many sexual couples exposure. In 2018, the number of HIV in Argorejo location has increased three times compared to 2017. The purpose of the study was to describe the source of female sex workers information media to act in an effort to prevent HIV / AIDS in the Argorejo Localization in Semarang City. This study used descriptive qualitative method. Data collection techniques was in-depth interviews. Population in this research is female sex workers in the Argorejo Localization, Semarang City. A descriptive phenomenological study was used describe the experience of female sex workers during in prostitution. Eleven female sex workers, a foster mother also two health workers as data resource triangulation to collect the data. This analysis also uses content analysis. Most of the sex workers have heard of HIV/AIDS from magazine, social media, sign or poster in dorm and from friends. HIV/AIDS cases that have occurred to the sex workers’ colleagues were one of the guides to behave or in other words considering the experience that has happened before is a strong predictor for behavior in the future.

The Role of the Government of East Jakarta City in the Control of TB-HIV and the Fulfillment of the Right to Health

TB-HIV eradication is one of Indonesia’s government role implementation to ensure the rights to health for its citizens. Jakarta Timur is the area in DKI Jakarta that has the highest number of TB cases and the second-highest number of HIV cases. This research is held to understand the regulation regarding the government’s role in TB-HIV eradication, implementation of government’s role in TB-HIV eradication, and factors that influence the implementation of the government’s role in TB-HIV eradication The research was conducted in the Jakarta Timur area, throughout health care offices and institutions. This study used a sociological juridical approach with analytical descriptive specifications. The data used are primary data through interviews and observation, also secondary data through field and literature studies. The study used the purposive sampling method which includes TB-HIV patients and healthcare providers in health care facilities. The result of the study indicates that regulation regarding the Jakarta Timur government’s role in TB-HIV eradication has been created however separately, HIV regulation in Peraturan Daerah DKI Jakarta No. 5 Tahun 2008 and TB regulation in Peraturan Gubernur DKI Jakarta No. 28 Tahun 2018. Moreover, the collaborative regulation that has been created in the form of Surat Edaran Suku Dinas Kesehatan Kota Administrasi Jakarta Timur No. 50053/1.772.11 , is not legally binding. Thus, the Government’s role in eradicating TB-HIV still encounters few factors that hinder its implementation thus the rights to health haven’t entirely fulfilled. Influencing factors are juridical, sociological, and technical factors. The juridical factors are the existence of regulation in TB-HIV eradication, however separately and the lack of legal binding in Surat Edaran to regulate TB-HIV eradication. The sociological factors are lack of patients’ medication compliance, healthcare provider’s stigma and violation of medical confidentiality. The technical factors are the TB-HIV collaboration team that hasn’t been arranged in health care facilities, overlap in TB-HIV reporting mechanism, availability of medication and funding that rely on donor’s contribution.

Trend of HIV/AIDS for the last 26\xa0years and predicting achievement of the 90\u201390-90 HIV prevention targets by 2020 in Ethiopia: a time series analysis

BackgroundHIV infection continues to be epidemic of public health importance with a prevalence of 1.1% and incidence of 0.33/1000 population having low-intensity mixed epidemic. Ethiopia has adopted the 90–90-90 by 2020 target but its progress was not yet assessed. Therefore, this study aimed to assess the trend of HIV infection for the last 26 years and to predict the achievements of the 90–90-90 target.MethodsWe used aggregates of HIV/AIDS indicator data from 1990 to 2016 of UNAIDS data bases. The data were analyzed with excel and STATA. The trend line that best fits the regression was drawn, annual change was estimated and future values of HIV detection rate, coverage of antiretroviral therapy and viral suppression indicators were predicted and compared with the 90–90-90 targets.ResultSince 1995, new infection has declined by 81% and since 2002; number of HIV cases has declined by 35.5%. However, after remarkable decline for decades, since 2008 HIV incidence rate began to rise by 10% and number of new infection diagnosed each year increased by 36% among all ages and doubled among adults. ART coverage has increased by 90% among all age and tripled among pregnant women within 6 years. Nationally, 67% of people living with HIV know their status, 88% of them are on treatment and 86% of people on treatment have viral suppression. As a result, AIDS-related death declined by 77 and 79% among all age and children respectively. By 2020, 79% of people living with HIV will know their HIV status, of which 96–99% of HIV infected people will be on ART and more than 86% will have viral suppression.ConclusionAfter remarkable decline, HIV infection started to increase in the last few years among adults. With the current trend, Ethiopia will achieve the second and third 90% HIV targets, while the first target is not achievable and without achieving this overarching goal control of the epidemic will not be achieved. Therefore due attention is needed to avert the current epidemics and diagnosis of cases.

Mapping Determinants of Virus Neutralization and Viral Escape for Rational Design of a Hepatitis C Virus Vaccine.

Hepatitis C virus (HCV) continues to spread worldwide with an annual increase of 1.75 million new infections. The number of HCV cases in the U.S. is now greater than the number of HIV cases and is increasing in young adults because of the opioid epidemic sweeping the country. HCV-related liver disease is the leading indication of liver transplantation. An effective vaccine is of paramount importance to control and prevent HCV infection. While this vaccine will need to induce both cellular and humoral immunity, this review is focused on the required antibody responses. For highly variable viruses, such as HCV, isolation and characterization of monoclonal antibodies mediating broad virus neutralization are an important guide for vaccine design. The viral envelope glycoproteins, E1 and E2, are the main targets of these antibodies. Epitopes on the E2 protein have been studied more extensively than epitopes on E1, due to higher antibody targeting that reflects these epitopes having higher degrees of immunogenicity. E2 epitopes are overall organized in discrete clusters of overlapping epitopes that ranged from high conservation to high variability. Other epitopes on E1 and E1E2 also are targets of neutralizing antibodies. Taken together, these regions are important for vaccine design. Another element in vaccine design is based on information on how the virus escapes from broadly neutralizing antibodies. Escape mutations can occur within the epitopes that are involved in antibody binding and in regions that are not involved in their epitopes, but nonetheless reduce the efficiency of neutralizing antibodies. An understanding on the specificities of a protective B cell response, the molecular locations of these epitopes on E1, E2, and E1E2, and the mechanisms, which enable the virus to negatively modulate neutralizing antibody responses to these regions will provide the necessary guidance for vaccine design.

DUKUNGAN SOSIAL TERHADAP KONSUMSI ARV IBU RUMAH TANGGA PENDERITA HIV DI SURABAYA

In 2014, East Java ranks second highest HIV cases in Indonesia to 32.872 the number of HIV cases. Concern HIV disease is exposed when in 2014 based on the sequence of work housewife ranks second HIV cases in Surabaya with the number of 129 cases. The case of a housewife who has HIV is higher compared to commercial sex workers. Therapeutic treatment for patients with HIV using antiretroviral drugs. ARV consumption serves to suppress the growth of HIV. This study was conducted to determine the social support for the consumptionof ARV housewife in Surabaya. The research is a qualitative research with case study approach. Informants used are numbered 9 consisting of three housewives with HIV, three families and three close friends housewife with HIV. The study was conducted from May to December 2016. Data collection using an interview guide and study documents. The results showed that there is social support for the consumption of housewives with HIV. Their diff erences in background,control beliefs, perceived behavioral control, intention-owned and social support received informants could aff ect the consumption of ARVs do informant. The conclusion that can be drawn is that the most infl uential social support for the consumption of ARV housewife with HIV in Surabaya is emotional support and support networks. Another eff ect of ARV consumption comes from a background that was once owned by housewives with HIV.Keywords: social support, consumption of ARV, housewife, HI

Variance in Global Response to HIV/AIDS between the United States and Japan: Perception, Media, and Civil Society

AbstractThe US and Japan, despite their shared reputation as leading donors for international development, remarkably varied in their foreign aid policy for HIV/AIDS in the 1980s and 1990s. Unlike the US, who initiated and increased global AIDS funding dramatically, Japan was lukewarm in its contributions. I claim that the distinctive pattern depends on how the pandemic was domestically framed and understood. The policy commitment was more likely when the internationally shared idea (international norms) of threats requiring immediate international cooperation was congruent with the domestic perception of the epidemic. The research undertakes a comparative examination of the determinants of the distinctive domestic perceptions of the two cases, including the number of individuals infected with HIV, the attitude and role of the media, and the civil society organizations dealing with HIV/AIDS. They played significant roles as intervening variables that conditioned domestic diffusion or internalization of the international norms for foreign aid policy development. The US had a favorable domestic condition based upon the relatively large number of those infected with HIV, a media that adopted a constructive approach, and active civil society organizations associated with the disease. In contrast, in Japan the number of HIV cases was lower, the media had a distorted view of the epidemic, and civil society organizations were not strong enough to offer much support until the early 1990s.

Tackling Drug-Resistant Tuberculosis: Current Trends and Approaches.

Tuberculosis is very much rampant in our society and accounts for a large number of deaths annually. In spite of consistent efforts being made, the disease has not been curtailed yet. The emergence of MDR and XDR strains in the society along with an increase in the number of HIV cases and that of latent TB, have further aggravated the problem making the disease very much persistent. The current situation clearly manifests the need to discover and develop new potent molecules/approaches that could help to tackle drug resistance. Various molecules, such as derivatives of fluoroquinolones (e.g. gatifloxacin, moxifloxacin and DC-159a), rifamycins (rifapentine), oxazolidinones (linezolid, sutezolid/PNU-100480), diarylquinolines (TMC207/bedaquiline), antifungal azoles, pyrrole (LL3858), nitroimidazopyran (PA824), nitroimidazole (OPC67683, TBA-354), diamine (SQ109) and benzothiazinone (BTZ043) are being developed in an attempt to combat the disease. This review presents a general introduction to the current status of the disease, the biology of the pathogen as well as the state of drug development against tuberculosis (TB) with emphasis on the major problems and bottlenecks associated with the same. Starting from the first drug against TB, the review discusses the entire history and the course of development of the drugs which are available today in the market as well as those which are under various phases of clinical and pre-clinical trials along with their mechanism of action. It also talks about the possible role of nanosciences in combating TB.

A qualitative analysis of multi-level barriers to HIV testing among women in Lebanon

While the number of HIV cases in the Middle East and North Africa region is low compared to other regions, recent studies show that incidence is increasing especially among high-risk populations; in particular, little is known about women and HIV in the region. Through semi-structured interviews with sexual healthcare providers and staff at non-governmental organisations, we sought to understand barriers to HIV testing among women in Lebanon. Using snowball sampling, key informants were recruited from greater Beirut (12 physicians, 9 non-governmental organisation staff). Data were analysed using a grounded theory framework. Findings identified barriers to HIV testing among women at each level of an adapted social-ecological model (i.e. social-cultural barriers, policy barriers, interpersonal healthcare provider barriers and intrapersonal barriers). Primary findings include the culture of sex as taboo; lack of sexual health education among women; fear of disclosing HIV testing and diagnosis; financial barriers linked to stigmatising insurance policies; and provider attitudes towards women. Findings can be used to inform HIV-related sexual health interventions at multiple levels for women in Lebanon and the greater region.

Number of HIV-infected cases in Iran: True or just an iceberg.

Background:The number of HIV cases in Iran is increasing. Knowledge of the changing epidemiology of HIV is fundamental for service planning and prevention activities. This study aims to estimate the number of HIV-infected cases by the capture and recapture method for size estimation.Materials and Methods:From 2002 to 2009, we used three different centers – hospitals, the Voluntary Counseling and Testing (VCT) center, and a central prison in Fars Province for data retrieval. The overlaps between these centers were investigated to determine the true estimate of HIV cases. Finally, interactions were analyzed by a linear logarithm model with STATA version 9 software.Results:We observed 5167 HIV cases. The number of males was ten times more than that of females. The most frequent age range was between 15 and 44 years. The majority of cases (n = 3347) were retrieved from the VCT center. The least number of infected persons were located in the prison and hospitals. The estimated number of cases in Fars Province was 14,925 from 2002 to 2009. The best model consisted of three sources.Conclusion:Covering the system of medicine deputy for registering the number of infected cases with HIV is poor in Iran. Improvements in making arrangements for enhancing the quality of data related to HIV-infected cases are essential for solving this problem and must be on the agenda for medical policymaking.

The Cost-Effectiveness of Integrating HIV Counseling and Testing into Primary Health Care in the Ukraine.

We estimate the number of HIV cases diagnosed, costs, and cost per HIV case detected associated with integrating HIV counseling and testing (HCT) into primary health care facilities in Ukraine. The study uses a difference-in-difference design with four districts implementing the intervention compared to 20 districts where HCT were offered only at specialized HIV clinics. There was a 2.01 (95% CI: 1.12-3.61) times increase in the number of HIV cases detected per capita in intervention districts compared to other districts. The incremental cost of the intervention was $21,017 and the incremental cost per HIV case detected was $369. The average cost per HIV case detected before the intervention was $558. Engaging primary health care facilities to provide HCT is likely desirable from an efficiency point-of-view. However, the affordability of the intervention needs to be assessed because expansion will require additional investment.