Molluscs have long been regarded as promising bioindicator and biomonitoring subjects for heavy metals as molluscs are highly tolerant to heavy metals and exhibit high accumulation in their body. In spite of several previous studies about the impact of cadmium on molluscs, little information exists in literatures concerning the toxic effects of cadmium on Lymnaea acuminata, especially pertaining to behavioral and hematological changes as these are considered effective bioindicators and biomonitoring variables for detecting heavy metals in polluted water bodies. In the present study, the median lethal concentrations of cadmium chloride to snail, Lymnaea acuminata, were estimated to be 9.66, 7.69, 6.26, and 5.54mg/L at 24, 48, 72, and 96h, respectively. For behavioral studies, variable test concentrations of cadmium from 0.00 to 10mg/L were used. The clumping tendency, crawling activity, and touch reflex in the exposed snails were gradually decreased with higher concentrations at 72 and 96h. For measuring the hemocyte numbers in the circulating hemolymph of snail during chronic cadmium exposure, two sublethal doses of cadmium (10 and 20% 96-h LC50-0.55 and 1.11mg/L, respectively) were used. A significant variation (p<0.05) from the control at all exposure times (7, 14, 21, and 28days) was recorded at 1.11mg/L concentration. The total count of circulating hemocytes was significantly reduced (p<0.05) compared to the controls at both concentrations of cadmium exposure at all time periods except 14 and 21days exposure at 0.55mg/L where values were non-significantly increased. In comparison between two sublethal doses, blood cells were significantly (p<0.05) lowered at 1.11mg/L cadmium treatment. Considering the behavioral and hematological data, it seems possible to forecast the physiological state of snails in cadmium-contaminated water bodies and these findings can be used in determining the safe disposal level of cadmium in aquatic ecosystem.