AbstractIonospheric maps from an optimal GNSS (global navigation satellite system) receiver network may lead to better understanding and prediction of the equatorial ionospheric gradients. An unsupervised machine learning framework is proposed using the ‐means clustering approach to optimize the available number of GNSS receivers. Beginning with = 15 receivers, the simulations are performed to obtain distribution of the ionospheric pierce points (IPPs) in different grid resolutions up to = 1,000. The algorithm uses a reference grid and subsequently optimizes the locations according to the available IPPs in a cluster. The IPP cluster centers are iteratively optimized based on minimizing the “within cluster sum of squares” error. The IPPs from the optimal receiver locations are used to generate a 2‐D vertical total electron content (VTEC) map using NeQuick‐G model. A one‐sigma confidence limit derived from hourly histogram of the IPPs from the locations is used as decisive criteria for useable grid cells. The number of empty bins thus obtained in a given scenarios provides a percentage normalized empty grid ratio (). A below 10% is used as a threshold to make a decision over eligibility of a scenario to produce a desired VTEC map. Several scenarios are thus tested for varying temporal and spatial grid resolutions, geographical boundaries, GNSS and NavIC satellite configurations, considering the diurnal and annual variation in year 2019. The framework is found to be successful in designing a GNSS network for any geographical region to obtain high resolution 2‐D VTEC maps for space weather applications.