Herbomineral is effective for a number of ailments from ancient times. Bhasma an effective herbomineral are highly potent, non-toxic and therapeutically beneficent medicines due to their unique method of preparation known as Samskara. Thereby by the metal particles are reduced to finer and finer sizes. Bhasma prepared by herbs, mineral, and metals are incinerated to ash under supervised conditions Prepared bhasma are subjected to physiochemical characterization using modern technical like elementary analysis with EDAX, SEM.TEM, TGA, XRD, AAS, etc. These studies reveal that Bhasma particles are in oxygen defective state and clearly noticeable particles fractions are in nanometre size range. These properties like oxygen defiant and nanoparticles in bhasma might disseminate therapeutic property.