A theory is developed for the rupture of Newtonian black films by a mechanism of nucleation of holes in these bimolecular foam films. The two film monolayers are considered as mutually adsorbed on each other and the film thermodynamic equilibrium is described by an adsorption isotherm in mean field approximation. Expressions are derived for the nucleation work, the steady-state nucleation rate, and the nucleation time lag of mono- and bilayer circular holes of critical size. A formula is obtained for the mean time for film rupture as a function of the activity (or the concentration) of surfactant in the bulk of the solution, and a critical activity (or concentration) for obtaining a Newtonian black film is defined. The present theory is directly applicable to the case of bilayer lipid membranes (BLM) which are a suitable model for studying the stability of biological membranes.