Using the Plastino-Plastino (PP) equation, we calculate transport coefficients of the heavy-quarks traversing inside the quark-gluon plasma, and generalize their relationship with differential energy loss. The PP equation indicates anomalous diffusion of the probe particles and yields a quasi-exponential stationary distribution obtained also from the nonadditive statistics proposed by C. Tsallis. We estimate energy loss in a nonadditive quark-gluon medium, and calculate the jet quenching parameter (qˆ) for the PP dynamics. With the help of the estimate of qˆ, we calculate the nuclear suppression factor (RAA) of the heavy-quarks passing through a nonadditive quark-gluon plasma using the model proposed by Dokshitzer and Kharzeev. In many a case, the parameters in the analysis are fixed from the experimental results to minimize arbitrariness. There is a good agreement between the theoretical calculation and experimental RAA data, indicating that fast heavy-quarks may be subjected to anomalous diffusion inside the QGP.