Astrophysical environments that reach temperatures greater than $\sim$ 100 keV can have significant neutrino energy loss via both plasma processes and nuclear weak interactions. We find that nuclear processes likely produce the highest-energy neutrinos. Among the important weak nuclear interactions are both charged current channels (electron capture/emission and positron capture/emission) and neutral current channels (de-excitation of nuclei via neutrino pair emission). We show that in order to make a realistic prediction of the nuclear neutrino spectrum, one must take nuclear structure into account; in some cases, the most important transitions may involve excited states, possibly in both parent and daughter nuclei. We find that the standard technique of producing a neutrino energy spectrum by using a single transition with a Q-value and matrix element chosen to fit published neutrino production rates and energy losses will not accurately capture important spectral features.