In the present study, a field experiment was laid out to assess the suitability of two short-duration varieties of red gram and standardize the agronomic management practices. The treatments included combinations of two varieties, two spacings, and three nutrient levels. Individual effects of the variety, APK 1, narrow spacing, and the highest nutrient level were found superior for yield and its contributing attributes. The pooled analysis registered the highest seed yield (1.38 t ha-1) in the combination APK 1 + 40 cm × 20 cm + 40:80:40 kg NPK ha-1. The net returns and benefit-cost ratio were also the highest. Soil available nutrient status was found to be augmented with the cultivation, with wider spacing and the highest nutrient dose recording maximum postharvest soil NPK contents. The results proved that the variety APK 1 and the agronomic management of 40 cm × 20 cm spacing with 40:80:40 kg NPK ha-1 are most suitable for red gram cultivation in southern Kerala.