This book does a great job of introducing the novice entrepreneur to—and preparing him or her for—the field (this novice generally being an advanced engineering, medical, or business student). The book begins with a section introducing the prospective entrepreneur to the importance of focusing on the envisioned end product’s value and then offers some insight into the global biodesign market. The main text is divided into three parts corresponding to the development phases of a biodesign product: “Identify,” “Invent,” and “Implement.” Each of these is expanded into two substages, which are then further expanded into specific activities related to each stage for a total of 29 design/develop/build/sell/et cetera chapters. Overall, this is an impressive text, both comprehensive and very well written. Over 60 examples are provided to elaborate upon the authors’ essential points. Each chapter is well illustrated; tables, in particular, are comprehensive and valuable in terms of design considerations. Chapters are also well referenced with notes. Additional notes and other reference materials as well as excellent supplementary videos may be found at ebiodesign.org, a website developed by the authors in collaboration with other contributors. This is a very useful text for the biodesign entrepreneur. In the education sector, I see the best primary use of this text being situations in which a multitalented team (e.g.,engineers, medical students, and business students) collaborate on a year-long, fairly involved project to drive items from concept to development prior to going to market. This could involve technology transfer grant work, guided master’s or Ph.D. degree-level design/development theses and dissertations, or contract work (given adequate funding). For the entrepreneur in academia or industry (or in the garage), this text a good guide to read and to follow.