To describe trends in case notification data for vaccine-preventable diseases in NSW for 2010. Risk factor and vaccination status data were collected from cases through public health unit follow-up. Data from the NSW Notifiable Conditions Information Management System (NCIMS) were analysed by: local health district of residence; age; vaccination status; and sub-organism, where available. Outbreaks of measles and pertussis were notified in 2010, associated with unimmunised groups (measles) or as a result of waning immunity (pertussis). With the exception of pertussis, most vaccine-preventable disease notifications remain low in NSW. Ensuring high levels of vaccination for travellers is important to prevent future outbreaks of vaccine-preventable disease, particularly measles.
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