Northwest Italy Research Articles

Interdisciplinary approach to solve unusual mortalities in the European common frog (Rana temporaria) in two high-mountain ponds affected by climate change

The global decline in amphibian populations is a major environmental issue. Chytridiomycosis, Ranaviruses and the red-leg syndrome have been identified in unusual mortality events. However, these infections do not account for all causes of declining amphibian populations. Moreover, several cases of amphibian mortality are difficult to solve without resorting to an interdisciplinary approach. Two cases of unusual mortality in Rana temporaria occurred at two high-mountain ponds (northwest Italy) in April and May 2021. Water and frog samples were analysed to understand the possible causes responsible for the unusual mortalities. Results of the main physicochemical (pH, conductivity, dissolved oxygen, chemical and biochemical oxygen demand) and nutrient (ammonia/ammonium, nitrite, nitrate, total phosphorus) parameters revealed a good condition of the water quality, with the absence of the main cyanotoxins (microcystins/nodularins). However, unseasonably high spring water temperatures were recorded in both ponds (12.73 °C and 14.21 °C for Frog Pond and Selleries Pond, respectively). Frogs (n = 50; snout–vent length: 7.0–9.8 cm; body mass: 85–123 g) collected from Frog Pond mainly presented bumps on the ventral cavity and dermal ulceration associated with the isolation of Carnobacterium maltaromaticum. On the other hand, frogs (n = 5; snout–vent length: 8.0–9.1 cm; body mass: 87–92 g) from Selleries Pond presented petechiae and dermal ulcerations on the rear limbs associated with the isolation of Aeromonas salmonicida and A. sobria. In both mortality events, the interdisciplinary approach revealed an association between frog mortalities and the isolation of bacteria. Isolated bacteria are considered opportunistic pathogens, and the high values of the water temperature has certainly led a stress on the frogs, favouring the spread of bacteria and the death of the frogs. Further studies are needed to assess the pathophysiological effects of the opportunistic bacteria here isolated, clarifying the interactions between emerging pathogens and climate change.

Featured Poet Kiki Petrosino: “The Red Earth of Terra”

Featured Poet Kiki Petrosino: “The Red Earth of Terra”

Clinical and Forensic Aspects of the Management of Child Abuse: The Experience of the Paediatric Emergency Department in Novara, North-West Italy.

Child abuse is an endemic phenomenon that refers to any form of violence aimed at children and adolescents. The Emergency Room is often the entry point to healthcare for the abused child. This is a cross-sectional study including minors, aged 0-18 years, of all genders, who experienced any form of violence examined at the Paediatric Emergency Department of the 'Maggiore della Carità' Hospital in Novara (North-West Italy) between 1 January 2017 to 31 December 2021. Data were extrapolated by looking at the diagnosis at discharge. A comparison of the different variables collected was made between the pre-COVID-19 period and the COVID era. 120 minors presented to the paediatric emergency room seeking help for violence. The average age was 10 years, 55% of the victims were male and 75% of them were Italian. In the pre-COVID period, the number of presentations for abuse was 62, while in the COVID period it was 58 with an increase of peer violence (from 38.71% to 62.07%) and with a statistically significant impact of the pandemic on the phenomenon (p-value < 0.00001). In general, peer violence accounts for 50% of the cases reviewed and resulted in fewer reports to the judicial authority and requests for forensic advice. The SARS-CoV-2-related pandemic has had an impact on total emergency room admissions and the types of abuse perpetrated.

Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy

The burden of inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-West Italy accounting for 57,615 inhabitants as of 31 December 2021. Clinical and demographic data were retrieved from administrative databases and the medical records of general practitioners (n = 39) at Verduno Hospital. Prevalence and incidence rates were calculated for the time span 2016-2021 and compared to the 2001-2006 period. IBD prevalence was 321.2 per 100,000 population in 2021 and, compared with 2006 (200 per 100,000 population), the prevalence has increased at a rate of +46%. Similarly, the average incidence has increased from the period 2001-2006 (6.7 per 100,000 population/year) to the period 2016-2021 (18.0 per 100,000 population/year) at a rate of +169%; such an increase was greater for CD than UC. In the 2016-2021 period, the mean age at diagnosis was 42.0 ± 17.4 years and 30.9% required at least one hospitalization, while 10.9% of patients underwent at least one surgery. In conclusion, the prevalence and incidence of IBD distinctly increased over a two decade period in the Healthcare District Bra paralleling the results of previous surveys from other Italian regions. These data warrant specific interventions to improve patients' management and resources' allocation.

Monitoring of Antimicrobial Resistance of Salmonella Serotypes Isolated from Humans in Northwest Italy, 2012-2021.

Salmonella enterica is among the most common causes of foodborne outbreaks in humans in Europe. The global emergence of resistance to antimicrobials calls for close monitoring of the spread and prevalence of resistant Salmonella strains. In this study, we investigated the occurrence of antimicrobial resistance of Salmonella serotypes isolated from humans between 2012 and 2021 in Piedmont, northwest Italy. A total of 4814 Salmonella strains (168 serotypes) were tested against six classes of antimicrobials. Many strains (83.3%) showed resistance to at least one antibiotic: tetracycline (85.1%), ampicillin (79.2%), quinolones (47.4%), and gentamicin (28.4%). Between the first (2012-2016) and the second study period (2017-2021), a decrease in antimicrobial resistance was noted for tetracycline (from 92.4% to 75.3%), ampicillin (from 85.3% to 71.3%), quinolones (from 49.4% to 44.6%), and cefotaxime (from 34.8% to 4.0%). Many multidrug resistant Salmonella strains (43.6%) belonged to S. ser. Typhimurium, S. ser. Infantis, and S. ser. Typhimurium 1,4,[5],12:i:-. Overall, multidrug resistance decreased from 60.7% to 26.4%, indicating a reduction in the antimicrobial resistance of Salmonella strains in Piedmont and in Europe and demonstrating the effectiveness of the measures that were put in place to reduce antimicrobial resistance.

Sociopolitical conflicts on the establishment of protected natural areas: The case of Portofino National Park (Genoa, North-West Italy)

&lt;abstract&gt; &lt;p&gt;This work traces the main stages of environmental and landscape protection of the Portofino Promontory, located in &lt;italic&gt;Riviera Ligure di Levante&lt;/italic&gt; (N-W Italy), with particular regard on the recent establishment of Portofino National Park. From 2017, when the institution law was enacted, to date, the park has not yet been established due to the socio-political conflicts that have arisen between some stakeholders and institutions of the territory. These conflicts include not only environmentalists against hunters and constructors but also disagreement between municipalities and region (&lt;italic&gt;Regione Liguria&lt;/italic&gt;) and between region and the Ministry of Environment. Today the situation is still stalled, and funds for a park larger than the current one (Portofino Regional Park) have not been allocated. In spite of this, the tug-of-war continues through legal actions. The aim of the article is to analyze the perception of the enlargement of the park by the community and local governance and how this is communicated by the press. The research was conducted through the analysis of the results of a questionnaire aimed at understanding the level of knowledge of the main functions of a national park and the position of the people with respect to it. Second, an analysis of the press was carried out to understand the narratives on this environmental measure. The results of the questionnaire showed a positive consensus toward the park, while press analysis showed little involvement of experts on the subject to foster a political debate without concrete arguments, which damaged the park's image.&lt;/p&gt; &lt;/abstract&gt;

Adaptive urbanism in ordinary cities: Gentrification and temporalities in Turin (1993–2021)

The aim of this paper is to ground gentrification processes within a broader urban transformation pattern and within a deeper historical account, taking an ordinary city into consideration: Turin, in the North West of Italy. The paper elaborates on qualitative data collected along a twenty year span, allowing reflection on different phases and dynamics of capital extraction across time. We will show that, problematically, gentrification was considered as a positive model by local authorities and that it was adopted as a reference by both private and public actors to generate local growth and to react to economic crises.

Combining energy dynamic simulation and multi-criteria analysis for supporting investment decisions on smart shading devices in office buildings

In the framework of the current energy transition, the building sector is experiencing a smart revolution, recognizing how the adoption of advanced control strategies and smart management systems can increase buildings energy efficiency and improve occupants’ comfort. As a key element for smart buildings, solar shading devices coupled with effective control systems need to be strategically assessed. The investment decision-making process for selecting the proper shading systems is influenced by the existence of potential conflicts from economic, environmental, social, and energy standpoints, thus asking to be supported by innovative methodological approaches able to include all these aspects in the decisional framework. To this purpose, the work aims to propose a multi-disciplinary methodological framework to support decision-makers in ranking a set of solar shading device and relative control strategy, integrating energy dynamic simulations with multi-criteria decision analysis techniques. The analysis focuses on office buildings, recognizing their huge impact in terms of energy consumptions and the need to guarantee proper indoor conditions to increase employees’ productivity and well-being. To test the applicability of the multi-step methodology for this building category, the proposed approach is applied to an office building located in the North-West of Italy, aiming to assess and compare different alternative combinations of shadings devices and management strategies. The advanced features of building energy modelling and simulation and the application of PROMETHEE II (Preference Ranking Organization METHod for Enrichment Evaluation II) method as multi-criteria analysis allows to provide recommendations to decision-makers to identify the systems to be installed, able to guarantee the best trade-off between internal comfort, operational energy, and environmental costs for the building under investigation.

The landscape impact of agricultural sheds in rural UNESCO site: Public preferences and mitigation solutions

The mitigation process of agricultural sheds into the landscape is crucial for aesthetic quality of its landscape and architectural integrity. The evaluation of how residents perceive these elements and identifying preferred solutions is crucial for landscape planning. For identifying sets of preferred mitigation solutions and defining shared criteria for landscape planning a representative sample of the population was investigated. We have estimated the willingness to pay for integrating contemporary agricultural sheds in a UNESCO landscape. Data were collected in six Core Zones of “Vineyard Landscape of Piedmont: Langhe-Roero and Monferrato” (North-West Italy). Preferences toward different mitigation measures of the agricultural sheds were investigated using a Discrete Choice Experiment (DCE) method. The DCE survey was carried out through face-to-face interviews involving 400 residents. The set of mitigation attributes (colour of the walls, colour of the roof, green barriers and plant green walls) was selected by means of a landscape analysis and presented to respondents using a set of images (close and distant views). Our study shows that the presence of green barriers (formal hedge and tree line) and the colour of the wall (green) are considered positive mitigation solutions. These attributes have a positive effect both in the close and the distant view. Our results confirmed that the distance may affect the visual impact of these buildings. Most of the respondents agree with the need to implement mitigation solutions for agricultural sheds, guaranteeing a better aesthetic enjoyment.

Glyphosate, glufosinate ammonium, and AMPA occurrences and sources in groundwater of hilly vineyards

Glyphosate [N-(phosphonomethyl) glycine] and glufosinate ammonium [ammonium dl-homoalanin-4-(methyl) phosphinate] are broad-spectrum, nonselective, post-emergence herbicides extensively used in various applications for weed control in both agricultural and non-crop areas. Aminomethylphosphonic acid (AMPA) is the major degradation product of glyphosate found in plants, water, and soil. Due to glyphosate's presumed low mobility, its monitoring in European water was limited. Recently both glyphosate and AMPA have been detected in several groundwater samples in Europe, U.S, Canada, Argentina, and China. Understanding the sources of these substances in water, especially in groundwater used for drinking, becomes a priority. In the present work the occurrences and the main drives of glyphosate, AMPA, and glufosinate ammonium in the groundwater of hilly vineyards located in the North-West of Italy were evaluated. Groundwater monitoring results showed frequent detection and concentrations above EQSGW for glyphosate and AMPA, while glufosinate ammonium was never detected. More frequent occurrences and higher concentrations were detected in the samples collected from wells located in the farmyards, most of them being used for irrigation and/or preparation of PPPs mixtures. Indeed, AMPA was the only compound detected in one groundwater well used for drinking, at values bellow EQSGw/DWQS. Such monitoring results were not expected as the modelling estimations under local pedoclimatic conditions indicated no risk of leaching to groundwater. However, the modelling performance and output may have been influenced by the non-consideration of important specific processes. Integrating monitoring and modelling results with information concerning the agricultural practices adopted and the wells use and location, possible contamination drivers were identified. These include the non-agricultural use of glyphosate in the farmyard, the point source contamination of wells and the possible transport with the subsurface lateral inflow of water from up-hill vineyard. This study strengthens the position of SETAC EMAG-Pest GW group concerning the necessity of spatial and temporal contextualisation of groundwater monitoring for a better understanding of its contamination drivers by PPPs.

A UNESCO Site as a Tool to Promote Local Attractiveness: Investigating Stakeholders’ Opinions

UNESCO World Heritage Sites are a useful tool to protect and promote the legacy human beings leave over the centuries. Ivrea, a 20th century industrial city, is the second Italian industrial site recorded in the UNESCO World Heritage List. It is a city in the North-West of Italy, historically known for the Olivetti factory, which made it world-famous by combining visionary ideals and a careful entrepreneurial policy. Our study focuses on the tourism value of the Ivrea UNESCO site and, in particular, aims at analyzing the level of integration of local stakeholders and their ability to identify guidelines for the promotion of the UNESCO site in terms of tourism. The research process was conducted with an in-depth analysis of the perception and consideration of public and private stakeholders concerning this topic. A questionnaire was prepared by a group of experts and individual interviews were conducted using the Delphi method; then, the results of the interviews were presented and the identification of priorities was carried out using the nominal group technique. Results show that the new UNESCO site in Ivrea has great potential, both in cultural terms, continuing the dissemination of Adriano Olivetti’s ideals, and in terms of tourism, because it may turn into a tourist attraction capable of generating new tourist flows and promoting the Olivetti approach.

Occurrence of antibiotic-resistant bacteria and resistance genes in the urban water cycle.

This study investigates the antibiotic resistance fate in the urban water cycle, evaluating the dynamics of antibiotic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) in three different full-scale wastewater treatment plants (WWTPs) and two drinking water treatment plants (DWTPs) located in the same geographical area (North-West of Italy). ARB (tetracycline-, ampicillin-, and sulfonamide-resistant bacteria) were quantified by plate counting and the abundances of selected ARGs (i.e., tetA, blaTEM, and sulII) and intI1 gene were measured using quantitative real-time PCR (qPCR). Higher concentrations of ARB and ARGs were observed in the WWTPs with respect to the DWTPs identifying the WWTP as hotspot for the spread of antibiotic resistances. Although a significant reduction of ARB and ARGs was observed in WWTPs and DWTPs after the treatment, none of the detected ARB or ARGs was completely removed in drinking water. The stability of the antibiotic-resistant rates between inlet and outlet associated with the reduction of relative ARG abundances underlined that both the treatments (WWTs and DWTs) did not apply any selective pressure. The overall results highlighted the importance to investigate the antibiotic resistance dynamics in aquatic ecosystems involved in urban water cycle integrating the information obtained by culture-dependent method with the culture-independent one and the need to monitor the presence of ARB and ARGs mainly in drinking water that represents a potential route of transmission to human.

Management of the Medico-Legal Dispute of Healthcare-Related SARS-CoV-2 Infections: Evaluation Criteria and Case Study in a Large University Hospital in Northwest Italy from 2020 to 2021

Healthcare-related SARS-CoV-2 infection is an issue of particular concern during the pandemic. It has important repercussions on the National Health System, which represents a source of medical-legal health disputes. In the healthcare context, there are reports of negative screening at hospital admission (via nasopharyngeal swabs) and subsequent diagnosis of SARS-CoV-2 infection during hospitalization. Such cases cannot be considered a priori of healthcare-related infections but require extensive in-depth evaluation. In this study, we propose an empirical classification to frame cases of SARS-CoV-2 infection diagnosed in the hospital (first negative admission swab, with subsequent positive test during hospitalization). The classification is based on five categories: nosocomial, probably nosocomial, indeterminate, probably community, and community cases. We analyzed patients who died after testing positive for SARS-CoV-2 during hospitalization (with initial negative screening) in the largest hospital in Northwest Italy from February 2020 to 31 December 2021. A total of 383 cases were tracked and are listed as follows: 41 cases (11%) were classified as nosocomial (i.e., 3.2% of COVID-19 deaths). In contrast, 71 cases (19%) were classified as probably nosocomial, 69 (18%) were indeterminate (i.e., the clinical, radiological, and laboratory characteristics did not provide information on the genesis of the infection), 166 (43%) were classified as probably community cases, and 36 (9%) were defined as community cases. Deceased patients with nosocomial SARS-CoV-2 infection constituted the following: 3.23% (41/1266) with respect to the total number of COVID-19 deaths, 1.1% (41/3789) with respect to those who entered the hospital with a negative swab and 0.82% (41/4672) with respect to the total of deaths from any cause of death. In this paper we discuss the topic and issues of nosocomial COVID-19 in hospitalized patients and address the medicolegal implications.

Regulation and policy-making for urban cultural heritage preservation: a comparison between Iran and Italy

PurposeDespite various comparative studies in the field of cultural heritage protection in the world, there is still a significant lack of comparative research on policies related to the legal system of countries' governance. The purpose of this study is to address the comparative policies in Iran and Italy, with a particular focus on the results of the executive experiences of two different types of policies in the cities of Oroumieh (North-West of Iran) and Turin (in North-West of Italy).Design/methodology/approachUtilising the comparative, analytical, bibliographic and descriptive historical research methodology, which is based on the study of the local, national and international comprehensive review of regulations and policy-making of cultural heritage preservation policies in Iran and Italy. In this research, the related documents in three languages (Persian, Italian and English) have been examined to compare profoundly and comprehensively the policies and regulations adopted in these two countries to be able to analyze the national and transnational regulations and local policies in the cultural heritage sector.FindingsIn addition to many cultural similarities and numerous commonalities, especially in the multiplicity of urban cultural heritage in historical centers, the results suggest that the legislation structure in Iran is much more centralized than in Italy. Also, the findings suggest that Italy focuses on aligning its previously centralized national legislative system in line with contemporary European heritage and preservation policies.Originality/valueThe paper outlines how to use historical and cultural similarities through comparative study to benefit the experiences of two historical countries in urban heritage conservation and policy-making part despite their differences.

Calibration of Methods for SARS-CoV-2 Environmental Surveillance: A Case Study from Northwest Tuscany.

The current pandemic has provided an opportunity to test wastewater-based epidemiology (WBE) as a complementary method to SARS-CoV-2 monitoring in the community. However, WBE infection estimates can be affected by uncertainty factors, such as heterogeneity in analytical procedure, wastewater volume, and population size. In this paper, raw sewage SARS-CoV-2 samples were collected from four wastewater treatment plants (WWTPs) in Tuscany (Northwest Italy) between February and December 2021. During the surveillance period, viral concentration was based on polyethylene glycol (PEG), but its precipitation method was modified from biphasic separation to centrifugation. Therefore, in parallel, the recovery efficiency of each method was evaluated at lab-scale, using two spiking viruses (human coronavirus 229E and mengovirus vMC0). SARS-CoV-2 genome was found in 80 (46.5%) of the 172 examined samples. Lab-scale experiments revealed that PEG precipitation using centrifugation had the best recovery efficiency (up to 30%). Viral SARS-CoV-2 load obtained from sewage data, adjusted by analytical method and normalized by population of each WWTP, showed a good association with the clinical data in the study area. This study highlights that environmental surveillance data need to be carefully analyzed before their use in the WBE, also considering the sensibility of the analytical methods.

Effects of Climate Change on Freshwater Biodiversity

This Special Issue intended to collect articles focusing on the assessment of the possible effects of climate changes on aquatic species inhabiting inland waters all over the world, including the possible synergistic effects in combination with other anthropogenic stressors. A total of six original articles were published that report on investigations of different freshwater ecosystems across the world, including the mountain streams of the Western United States and Northwest Italy, river basins of Northwest China and Central Italy, a larger lowland river in north Italy, and a high-elevation temporary pond in Central Italy. In most of these papers, special attention was devoted to the repercussions of the climate change and its effects on three important components of the biotic community: the fish, benthic macroinvertebrates, and zooplankton. According to the aims of this Special Issue, three of the articles offer new insight into the synergistic effects of global warming together with other anthropogenic stressors, including water exploitation and alien species invasions. In light of the studies’ aim to highlight the effects of climate change, three papers provided analyses of environmental data collected through long-term monitoring. The scientific findings provided by these studies could help to create sound management strategies for freshwater biodiversity conservation.

Oncological patient management on the territory: the results of a survey in the north-west of Italy.

To investigate the role of community pharmacists in the therapeutic process of oncological patients and to assess these patients' state of acceptance of their disease and their relationship with their therapies, we performed a survey in some oncological clinics in Turin (north-west of Italy). The survey was carried out in a three months' period by means of a questionnaire. The questionnaire was administered on paper to oncological patients that attended 5 oncological clinics in Turin. The questionnaire was self-administered. 266 patients filled out the questionnaire. More than half of patients reported that their cancer diagnosis interfered with normal life very much or extremely and almost 70% of patients reported that they were accepting of what happened and were trying to fight back. 65% of patients answered that it is important or very important that pharmacists are aware of their health status. About 3 out of 4 patients thought that pharmacists giving information on medicines purchased and on how to use them is important or very important and that it is important to receive information concerning health and the effects of medication taken. Our study underlines the role of territorial health units in the management of oncological patients. It can be said that the community pharmacy is certainly a channel of election, not only in cancer prevention but also in the management of those patients who have already been diagnosed with cancer. More comprehensive and specific pharmacist training is necessary for the management of this type of patient. Furthermore, it is necessary to improve the awareness of this issue in community pharmacists at the local and national levels by creating a network of qualified pharmacies developed in collaboration with oncologists, GPs, dermatologists, psychologists and cosmetics companies.

Antimicrobial Resistance of Salmonella Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018-2020 in the Northwest of Italy.

Antimicrobial resistance is one of the most challenging public health problems worldwide, and integrated surveillance is a key aspect in a One Health control strategy. Additionally, Salmonella is the second most common zoonosis in Europe. We aimed to investigate the circulation of Salmonella strains and their related antimicrobial resistance in human, environmental, and wild boar samples from the northwest of Italy, from 2018 to 2020, to obtain a more comprehensive epidemiological picture. Salmonella Typhimurium 1,4,[5],12:i:-, S. Veneziana and S. Newport were the most common serotypes occurring in humans, the environment, and wild boar, respectively. Antimicrobial resistance was rather common in Salmonella isolates, with those from human displaying the highest degree of resistance against sulfadiazine-sulfamerazine-sulfamethazine (&gt;90% of resistance). Moreover, resistance against azithromycin were exclusively observed in environmental samples, while only 7.7% (95% CI = 1.6-20.8) of wild boar isolates experienced resistance against trimethoprim-sulfamethoxazole. Multidrug resistance concurrently involved up to seven antimicrobial classes in human isolates, including third-generation cephalosporins and fluoroquinolones. Salmonella Typhimurium in humans and serotypes Goldcoast and Rissen from environmental sources showed the highest levels of resistance. This study shows diverse antimicrobial resistance patterns in Salmonella strains isolated from different sources and gives a broad picture of antimicrobial resistance spread in wild animals, humans, and the environment.

Replacing Agricultural Diesel Fuel with Biomethane from Agricultural Waste: Assessment of Biomass Availability and Potential Energy Supply in Piedmont (North-West Italy)

Agricultural and livestock wastes are an important resource for the production of renewable fuels such as biomethane, and the effective management of the components of supply chain, such as available biomass feedstock, are critical to the transition to a low-carbon circular economy. Considering that more than half of the emissions (CO2eq) generated in agriculture come from the use of fossil fuels to power tractors and other agricultural machinery, replacing diesel fuel in tractors with biofuels produced within the agricultural supply chain could contribute to greenhouse gas emissions reduction and to energy self-sufficiency for the local agricultural sectors. This study evaluated, at the regional level (Piedmont—north-west Italy), the potential production of biomethane from local agricultural wastes (crop residues and livestock manure), the potential energy supply to power tractors and the potential CO2 emission reduction by replacing diesel fuel. Based on mean annual available agricultural wastes over the last seven years (2015–2021) in the Piedmont region, the annual potential biomethane yield of 910 × 106 m3 year−1 was estimated, equivalent to a thermal energy of 30.1 × 109 MJ year−1, which is 3.8 times higher than the energy requirements for the regional tractors’ fleet. The estimated potential CO2 emission reduction is about 93.8 t of CO2 year−1, corresponding to 16.8% potential reduction. The study demonstrates the potential of local agriculture to replace diesel fuel with biomethane from waste to meet energy needs and carbon neutrality.

Who were the losers and winners during the Covid-19 pandemic? The rise of remote working in suburban areas

ABSTRACT The Covid-19 pandemic has rapidly altered the habits and lifestyles of every citizen worldwide and will have effects in the medium to long terms. The need for ‘social distancing’ has negatively affected urban areas and encouraged a rescheduling of working methods. Knowledge-intensive activities have been massively undertaken on a large scale in remote working, mainly carried out at home. Within this context, the paper explores the changes in working modalities towards remote working by focusing on the Lombardy region in north-west Italy. Specifically, it explores the renewed suitability of the municipalities outside the regional capital city of Milan with regard to remote workers during the pandemic and compares it with the period before the pandemic, and also it analyses which determinants play a role. The results show that municipalities closer to Milan with a strong broadband connection, a high concentration of knowledge workers and foreign immigrants are more suitable for hosting remote workers.