The discovery of the “ruins” of Guatacondo, in the Atacama Desert of northern Chile, made the news in 1963. It was the pinnacle of a process of scientific colonization of this territory that had begun in the 19th century and connected multiple experts with the desert and its history. This paper explores the context of discovery of an archaeological site in the Atacama to show how archaeology—as a field of knowledge and a scientific practice—emerged in the interstices of projects of colonial expansion and capitalist modernization, often merging public and private interests. Weaving together histories of scientific explorations, museum operations, and extractivist enterprises, it highlights deep connections between geopolitics and ideology with the seemingly apolitical and objective nature of archaeology. Starting with the peripheral figure of Emil de Bruyne—an engineer employed by one of the biggest mining operations in the Atacama Desert of northern Chile—we explore the role of different actors within a network of well-connected people whose personal histories, intellectual backgrounds, and personal positions gave shape to the practice of archaeology in this part of the Atacama Desert.