Hydraulic fracturing is today the primary means of initiating, increasing, and maintaining well productivity in unconventional shale gas reservoirs. However, hydraulic fracturing is attracting public concern over its rapid growth in use and environmental footprint, including potential hazards such as induced seismicity. To mitigate these concerns, there is a need to better understand the level of hazard present with respect to the magnitudes of the events possible, recognizing that these are not equal across different shale gas plays due to regional differences in the geological conditions or even within the same shale gas play due to local differences.An empirical study is presented here along with a series of numerical simulations to investigate the influence of the tectonic stress regime on the magnitude and magnitude distribution of induced seismicity events related to hydraulic fracturing practices. A database of determined earthquake focal mechanisms was first used to determine the tectonic stress regime for different North American shale gas basins. Next, induced events associated with hydraulic fracturing operations were identified to determine the magnitude distributions and b-values for these different shale gas basins. To support these empirical analyses, 3-D numerical modelling was performed to further investigate the mechanistic responses and event magnitudes under different simulated stress regimes. The empirical analysis results show that thrust faulting stress regimes have lower b-values than strike-slip stress regimes and therefore are more susceptible to larger induced seismicity events. The numerical simulations show that this is related to the stresses acting on a thrust fault (relative to the fault dip angle) being higher and more concentrated across a larger slip area. Slip in this case, and the stored strain energy being released, was observed to occur as a single large magnitude event. In contrast, numerical simulations for the other faulting types showed the stresses to be more distributed across the fault plane. This results in multiple slip events involving smaller slip areas and therefore with smaller event magnitudes, assuming all other factors are kept the same.