North Africa Research Articles

A new canid host for subcutaneous ticks: A report from Algeria in an African golden wolf (Canis lupaster)

BackgroundTicks are hematophagous ectoparasites that feed on the skin surface of their host. Subcutaneous localizations of ticks have predominantly been associated with red foxes, documenting new cases still brings new and potentially valuable data for tackling this unusual situation. The objective of this study is to report the presence of subcutaneous ticks in a new host and on a new continent. MethodsBetween February 2022 and September 2023, 47 road-killed animal carcasses belonging mostly to carnivorous species were subjected to a comprehensive parasitological necropsy. Upon detection of subcutaneous tick, the protuberance was excised, dissected, and preserved in labeled vials containing ethanol. Identification of the subcutaneous tick was carried out at the species level. ResultsA single nodule of subcutaneous ticks was found in an African golden wolf (Canis lupaster) collected from Northern Algeria; no other cases of unusual tick locations were observed. Based on morphological criteria the tick was identified as Ixodes ricinus / I. inopinatus. ConclusionThis study represents the first documentation of subcutaneous tick in an African golden wolf (Canis lupaster), thereby broadening the host spectrum for this atypical location. Furthermore, it underscores North Africa as a new geographical area where this phenomenon occurs.

General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants

Adiposity can be measured using BMI (which is based on weight and height) as well as indices of abdominal adiposity. We examined the association between BMI and waist-to-height ratio (WHtR) within and across populations of different world regions and quantified how well these two metrics discriminate between people with and without hypertension. We used data from studies carried out from 1990 to 2023 on BMI, WHtR and hypertension in people aged 20-64 years in representative samples of the general population in eight world regions. We graphically compared the regional distributions of BMI and WHtR, and calculated Pearson's correlation coefficients between BMI and WHtR within each region. We used mixed-effects linear regression to estimate the extent to which WHtR varies across regions at the same BMI. We graphically examined the prevalence of hypertension and the distribution of people who have hypertension both in relation to BMI and WHtR, and we assessed how closely BMI and WHtR discriminate between participants with and without hypertension using C-statistic and net reclassification improvement (NRI). The correlation between BMI and WHtR ranged from 0·76 to 0·89 within different regions. After adjusting for age and BMI, mean WHtR was highest in south Asia for both sexes, followed by Latin America and the Caribbean and the region of central Asia, Middle East and north Africa. Mean WHtR was lowest in central and eastern Europe for both sexes, in the high-income western region for women, and in Oceania for men. Conversely, to achieve an equivalent WHtR, the BMI of the population of south Asia would need to be, on average, 2·79 kg/m2 (95% CI 2·31-3·28) lower for women and 1·28 kg/m2 (1·02-1·54) lower for men than in the high-income western region. In every region, hypertension prevalence increased with both BMI and WHtR. Models with either of these two adiposity metrics had virtually identical C-statistics and NRIs for every region and sex, with C-statistics ranging from 0·72 to 0·81 and NRIs ranging from 0·34 to 0·57 in different region and sex combinations. When both BMI and WHtR were used, performance improved only slightly compared with using either adiposity measure alone. BMI can distinguish young and middle-aged adults with higher versus lower amounts of abdominal adiposity with moderate-to-high accuracy, and both BMI and WHtR distinguish people with or without hypertension. However, at the same BMI level, people in south Asia, Latin America and the Caribbean, and the region of central Asia, Middle East and north Africa, have higher WHtR than in the other regions. UK Medical Research Council and UK Research and Innovation (Innovate UK).

Assessing the impact of hydrogen trade towards low-carbon energy transition

Hydrogen is increasingly recognized as a pivotal commodity in the low-carbon energy transition, bridging regional disparities in hydrogen production capacity and facilitating international energy trade. Existing research has yet to delve into the impact of global hydrogen trade on energy transitions, as well as the key factors driving the development of hydrogen trade. This study, utilizing the updated GCAM-TU model, which mainly extends the original Global Change Analysis Model (GCAM) with a hydrogen trade module, provides a multi-scenario outlook on the characteristics of hydrogen trade and its impact on global and regional energy transition. The findings indicate that by 2050, the global hydrogen trade volume is expected to reach 9-19EJ, accounting for a quarter of the global hydrogen consumption in different scenarios, with green hydrogen trade dominating due to its cost advantages. Pipeline hydrogen and ammonia shipping will govern the trade market, representing 33%–61% and 24%–64% of trade volume, respectively, while liquid hydrogen shipping holds an advantage for medium distances. Hydrogen trade is projected to increase global hydrogen demand by 1.2–5.3EJ and reduce hydrogen prices by 11%–36% in the European Union, Japan, and South Korea, thereby expanding their hydrogen consumption by 8%–55% and reducing regional carbon prices by 1%–6%. Moreover, hydrogen trade significantly alters the regional distribution of global hydrogen production, with major exporting regions such as North and East Africa increasing their hydrogen production for export by up to 150%. To facilitate the development of hydrogen and hydrogen trade, it is crucial for potential importing and exporting regions to enhance global financial and technological cooperation, develop key hydrogen production and transportation technologies, and retrofit existing nature gas infrastructure to reduce costs. Additionally, forming stable trade partnerships is essential for maintaining energy security in the hydrogen trade.

Diagnostic challenges and outcome of fatty acid oxidation defects in a tertiary care center in Lebanon

BackgroundFatty acid oxidation defects are rare autosomal recessive disorders with variable clinical manifestations and outcome. Early detection by systematic neonatal screening may improve their prognosis. Long-term outcome studies of these disorders in the Middle East and North Africa region are limited. The purpose of this study is to report the diagnostic challenges and outcome of fatty acid oxidation defects in a major tertiary care center in Lebanon, a resource-constrained country in the Middle East.MethodsA retrospective review of charts of all fatty acid oxidation defects sequential patients diagnosed and followed at our center was conducted. Collected data included: parental consanguinity, age at diagnosis, clinical presentation, biochemical profile, confirmatory diagnosis, treatment and outcome. A genotype–phenotype correlation was also performed, when available.ResultsSeven types of fatty acid oxidation defects were identified in a total of 34 patients from 21 families. Most families (79%) were consanguineous (first-degree cousins). The majority were diagnosed when clinically symptomatic (78%), at various ages between 10 days and 19 years (average: 2 years). Follow-up duration spanned between 2 months and 15 years (average: 5 years). The remainder of the patients were detected while still asymptomatic by systematic neonatal screening (9%) or due to positive family history (9%). The most common defect was carnitine transporter deficiency (50%) with an exclusive cardiac presentation related to a founder variant c.981C > T, (p.Arg254*) in the SLC22A5 gene. Medium chain acyl-CoA dehydrogenase deficiency was found in 13% only, which could be explained by the absence of systematic neonatal screening. Rare gene variants were detected in very long chain and multiple acyl-CoA dehydrogenase deficiency. The worse prognosis was observed in very long chain acyl-CoA dehydrogenase deficiency. The overall survival at last follow-up reached 75% with a complete reversal of symptoms with treatment in most patients (63%), despite their late diagnosis.ConclusionsOur experience highlights the diagnostic challenges and outcome of fatty acid oxidation defects in a resource-constrained country with high consanguinity rates. Physicians’ awareness and systematic neonatal screening are key for diagnosis. Larger genotype–phenotype studies are still needed to understand the natural history of these rare diseases and possibly improve their outcome.

Risk assessment and categorization of terrorist attacks based on the Global Terrorism Database from 1970 to 2020

Risk assessment and categorization of terrorist attacks can assist enhance awareness of terrorism and give crucial information support for anti-terrorism efforts. This study utilizes quantitative approaches for the risk assessment and categorization of terrorist attacks. A total of 210,454 terrorist attacks that occurred worldwide from 1970 through 2020 were collected in the Global Terrorism Database, and 22 indicators related to the risk of terrorist attacks were selected. Then, the moment estimation theory and four comprehensive evaluation models were utilized to identify the top 10 riskiest terrorist attacks in the world. Furthermore, the five clustering analysis methods and three evaluation criteria were performed for the risk categorization of terrorist attacks, and the visual analysis was carried out using the kernel density estimation method. The research results have identified the top 10 riskiest global terrorist attacks, which were led by the September 11 terrorist attack event, along with their downward counterfactual events. The spatial distribution of global terrorist attack risk is primarily composed of four “turbulent cores” in the region of Central Asia, Middle East & North Africa, South Asia, and Central America & Caribbean. This study also provided insights and recommendations for anti-terrorism efforts. It has realized the risk assessment and categorization of terrorist attacks, aiding in the swift identification of its risk levels, and holds immense significance for safeguarding global national security and societal stability under new circumstances.

Interview: Reflections on Three Decades of Islamic Nonviolence

Abstract This article comprises a discussion with Prof. Mohammed Abu-Nimer, a trailblazer in the field of Peace Studies focusing on Islam and Muslim communities. It explores Prof. Abu-Nimer's reflections on the development of this field over the past three decades. It focuses in particular on methodological, institutional, and inter-cultural challenges and developments during that time. Like Prof. Abu-Nimer's long career, it is international in scope and explores convergences and divergences in the experiences and discourses surrounding Muslim-led nonviolent resistance, peacemaking and peacebuilding initiatives in the Middle East and North Africa, South Asia, and Sub-Saharan Africa. It also includes discussion of the role played by cultural difference and hybridity in translating the distinct peace and nonviolence repertoires of Western and non-Western cultural and political contexts.

Corporate social responsibility impact on customer-based brand equity in the Moroccan luxury hotel context: mediating role of customer value co-creation

Purpose This study aims to examine the impact of corporate social responsibility (CSR) on customer-based brand equity (CBBE), with a focus on the mediating role of customer value cocreation (CVCC). The objective is to understand the direct and indirect links between CSR and the dimensions of CBBE (image, quality, awareness, loyalty) in the context of the luxury hotel industry, thus filling existing gaps. Design/methodology/approach This quantitative study of luxury hotel guests in Morocco used a questionnaire. After a pilot study with 10 professionals, the final version was administered, generating 204 valid responses. Purposive convenience sampling was chosen. PLS analysis was favored. Findings The results highlight the significant influence of CSR on the four dimensions of CBBE. Likewise, CVCC exerts a significant effect on CBBE aspects, except for brand loyalty. CVCC partially mediates the relationship between CSR and brand image, perceived quality and brand awareness. However, it does not have a significant mediating role in the CSR−brand loyalty relationship. Research limitations/implications The study, despite its contributions, is limited to the luxury hotel industry in Morocco, raising concerns of external validity. Future research should diversify service contexts and explore the multidimensionality of CSR. Practical implications Luxury hotel managers should prioritize authentic communication to optimize their CBBE through CVCC. An inclusive and strategic approach to cocreation is essential to strengthen the impact of CSR on CBBE. Integrating CSR into customer touchpoints and human resources policies is crucial. Originality/value This study, to the best of the authors’ knowledge, enriches understanding of the complex interactions between CSR, CVCC and CBBE in Morocco and North Africa. Its originality lies in its exclusive contribution to the region’s marketing literature, broadening the field of knowledge. By exploring these relationships in the specific context of the region, it offers new perspectives to researchers and practitioners interested in CSR, CVCC and CBBE.

Knowledge gaps related to HIV and condom use for preventing pregnancy: a cross-sectional study among migrants in Sweden

BackgroundInformation and knowledge of sexual and reproductive health and rights (SRHR) plays a crucial role in promoting safe sexual practices among young migrants. We aimed to assess the sociodemographic factors of migrants associated with knowledge of condoms and the prevention, treatment, and transmission of HIV to highlight the need for SRHR information, including comprehensive sexual health education.MethodsA cross-sectional survey was conducted (2018–2019) among migrants at Swedish language schools and high schools across Sweden. The survey included questions about knowledge of condom use for preventing pregnancy and HIV treatment and transmission. Descriptive statistics were calculated, and multivariable logistic regression analyses were performed to assess the responses to the knowledge questions and sociodemographic characteristics.ResultsOut of 3430 respondents (median age: 35, interquartile range: 20), approximately 39% were unaware that condoms can prevent unplanned pregnancies. Only 58% of the respondents knew that condoms reduce the risk of contracting HIV. About 77% were unaware of HIV treatment, and 52% reported not knowing that a woman with HIV could transmit the virus to her baby during pregnancy or breastfeeding. Incorrect knowledge about condom use to prevent unwanted pregnancy was associated with several factors: younger age (15–19 years) adjusted odds ratio (aOR) 1.35; 95% confidence interval (CI), 1.02–1.79); female respondents (aOR: 1.68; 95% CI 1.36–2.07); lack of previous sexual health education (aOR: 2.57; 95% CI 2.11–3.13); low level of education (aOR: 1.30; 95% CI 1.04–1.61). Originating from the Americas, European, or sub-Saharan African regions was associated with a 34–42% decreased likelihood of incorrect knowledge that condoms can reduce the risk of HIV infection compared to respondents from the Middle East and North Africa (MENA). More than half (64%) of respondents reported needing more SRHR information.ConclusionsWe found significant knowledge gaps on HIV and condom use for preventing pregnancy among migrants in Sweden. Comprehensive sexual health education in language schools, along with information to newly arrived migrants from diverse regional backgrounds and targeted sexual health services to younger individuals, women, and those who lack sexual health education, are needed to address these information gaps and provide crucial SRHR education and information.

One third of African rivers fail to meet the ’good ambient water quality’ nutrient targets

The ambition of Sustainable Development Goal (SDG) target 6.3 is to improve global water quality by 2030. SDG indicator 6.3.2 monitors progress towards this target by assessing water bodies against ‘good’ ambient water quality criteria, with nutrients (nitrogen and phosphorus) as part of the key metrics. However, large data gaps present a fundamental challenge, especially for Africa on how to assess the progress being made with respect to both the current and desired future situations. Here, a continental water quality model for Africa is presented to simulate river sediment load, Total Nitrogen (TN) and Total Phosphorus (TP) loads and concentrations. Furthermore, critical areas and hotspots of TN and TP pollution are mapped for the period 2017 – 2019, in relation to the United Nations Environment Programme (UNEP) target thresholds used for the assessment of SDG indicator 6.3.2. Utilizing the UNEP’s criteria, which designates a water body as having “good ambient water quality” if 80% or more of its monitored values meet their targets, it is estimated that 44 % and 15 % of African rivers fail to meet the set water quality thresholds for simulated TP and TN, respectively. When synthesizing data for both TP and TN, 34 % of the rivers do not qualify as having “good ambient water quality”. Geographically, the most pronounced nutrient pollution hotspots were in North Africa, Niger River Delta, Nile River basin, Congo River basin and specific zones in Southern Africa. These areas correlate with regions characterized by high inputs of fertilizers, manure and wastewater discharge.

Female economic participation and sustainable development in African countries: The moderating role of governance

AbstractThis study examines the impact of female economic participation on sustainable development and the moderating role of governance in African countries using data between 2002 and 2022. Despite the significant contributions of women to the economy, they remain underrepresented in economic governance. The study employs the two‐step dynamic system GMM approaches with fixed effects and Driscoll–Kraay standard errors, and to address potential endogeneity. The findings reveal that while female economic participation positively affects sustainable development, poor governance weakens this relationship, suggesting a substitutive rather than complementary role of governance. The study establishes a governance threshold of 2.667, on a scale of 0–5, above which female economic participation significantly enhances sustainable development. Subregional analyses indicate varying impacts, with governance complementing female economic involvement in Central and Southern Africa but acting as a substitute in East, North, and West Africa. These insights underscore the need for enhanced governance and targeted policies to empower women and promote sustainable development across the African continent and the need for incorporating context.

Understanding the response of tropical overturning circulations to greenhouse gas and aerosol forcing

Abstract While observational records provide evidence for strengthening of the Pacific Walker circulation and the boreal winter Hadley cell (HC) over the last few decades, the underlying causes are not well understood. This study investigates the radiative effects of CO2 and anthropogenic aerosols on regional variations in the intensity of tropical meridional (Hadley-like) and zonal (Walker-like) overturning circulations, based on a suite of experiments using the IITM Earth System Model (IITM-ESM) along with supplementary analysis of observed and reanalysis datasets. Two key findings emerge from our study (i) strengthening of the Pacific Walker circulation with enhanced zonal sea surface temperature (SST) gradients and precipitation increase over the tropical Indo-Pacific, in response to global warming via ocean-atmosphere coupled feedbacks (ii) aerosol-induced intensification of regional meridional overturning circulation over the (0 − 120◦E) longitudinal domain resulting from inter hemispheric energy imbalance and southward shift of the southern hemispheric (SH) rainfall belt extending eastward from Africa across the Indian Ocean. Our results suggest that the combined radiative influence of increased CO2 and northern hemispheric (NH) anthropogenic aerosols reinforces the regional meridional overturning circulation, by enhancing convection over the SH and promoting widespread descent over the NH subtropics and mid-latitudes covering northern Africa, Mediterranean, parts of middle-East, West and South Asia. The present findings have important implications for the regional water resources, agriculture and environment.

Genome Tunisia Project: paving the way for precision medicine in North Africa

BackgroundKey discoveries and innovations in the field of human genetics have led to the foundation of molecular and personalized medicine. Here, we present the Genome Tunisia Project, a two-phased initiative (2022–2035) which aims to deliver the reference sequence of the Tunisian Genome and to support the implementation of personalized medicine in Tunisia, a North African country that represents a central hub of population admixture and human migration between African, European, and Asian populations.The main goal of this initiative is to develop a healthcare system capable of incorporating omics data for use in routine medical practice, enabling medical doctors to better prevent, diagnose, and treat patients.MethodsA multidisciplinary partnership involving Tunisian experts from different institutions has come to discern all requirements that would be of high priority to fulfill the project’s goals. One of the most urgent priorities is to determine the reference sequence of the Tunisian Genome. In addition, extensive situation analysis and revision of the education programs, community awareness, appropriate infrastructure including sequencing platforms and biobanking, as well as ethical and regulatory frameworks, have been undertaken towards building sufficient capacity to integrate personalized medicine into the Tunisian healthcare system.ResultsIn the framework of this project, an ecosystem with all engaged stakeholders has been implemented including healthcare providers, clinicians, researchers, pharmacists, bioinformaticians, industry, policymakers, and advocacy groups. This initiative will also help to reinforce research and innovation capacities in the field of genomics and to strengthen discoverability in the health sector.ConclusionsGenome Tunisia is the first initiative in North Africa that seeks to demonstrate the major impact that can be achieved by Human Genome Projects in low- and middle-income countries to strengthen research and to improve disease management and treatment outcomes, thereby reducing the social and economic burden on healthcare systems. Sharing this experience within the African scientific community is a chance to turn a major challenge into an opportunity for dissemination and outreach. Additional efforts are now being made to advance personalized medicine in patient care by educating consumers and providers, accelerating research and innovation, and supporting necessary changes in policy and regulation.

Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2

Nasopharyngeal carcinoma (NPC) is a malignant tumor of epithelial origin in head and neck with high incidence rate in South China, Southeast Asia and North Africa. The intervention of tumor-associated macrophages (Mφs) (TAMs)-mediated immunosuppression is a potential therapeutic strategy against tumor metastasis, but the exact mechanisms of TAM-mediated immunosuppression in nasopharyngeal carcinoma are unclear. Furthermore, how TAM affects the occurrence and development of nasopharyngeal carcinoma through metabolism is rarely involved. In this work, we revealed that NPC cells promoted M2-type Mφ polarization and elevated itaconic acid (ITA) release. Also, TAMs facilitated NPC cell proliferation, migration, and invasion through immune response gene 1 (IRG1)-catalyzed ITA production. Then, IRG1-mediated ITA production in TAMs repressed the killing of CD8+ T cells, induced M2-type polarization of TAMs, and reduced the phagocytosis of TAMs. Moreover, we demonstrated ITA played a tumor immunosuppressive role by binding and dampening ten-eleven translocation-2 (TET2) expression. Finally, we proved that ITA promotes NPC growth by facilitating immune escape in CD34+ hematopoietic stem cell humanized mice. In Conclusion, TAM-derived ITA facilitated NPC progression by enhancing immune escape through targeting TET2, highlighting that interfering with the metabolic pathway of ITA may be a potential strategy for NPC treatment.

Regional Heterogeneity of the Results of Glucagon-Like Peptide 1 Receptor Agonist Trials in Type 2 Diabetes: A Reanalysis of Individual Participant Data.

Multiregional trials are designed under the assumption that treatment effect applies to the entire target population, yet several factors may introduce geographic heterogeneity in treatment effect. We explored whether such variations exist in trials assessing the efficacy of glucagon-like peptide 1 receptor agonists (GLP-1RAs) in major cardiovascular events (MACE) in type 2 diabetes. A systematic search of Medline and the Cochrane Library was conducted from inception until 30 June 2020. We included international randomized controlled trials comparing any GLP-1RA versus placebo, with MACE as a primary end point. Individual participant data were subsequently requested from the sponsor or through data sharing platforms. For each trial, we calculated hazard ratios (HRs) and their 95% CIs for MACE, subgrouped by region. We then performed a random-effects meta-analysis and conducted meta-regressions to assess the influence of predetermined variables of interest on treatment effect. We included six trials including 45,426 patients. Baseline risk of MACE ranged from 2.9 per 100 patient-years in Southern Asia to 7.4 per 100 patient-years in Sub-Saharan Africa. HRs for MACE ranged between 0.25 (95% CI 0.05, 1.12) in Northern Africa to 0.98 (0.79, 1.22) in Western Europe. There was no significant subgroup difference across regions (P = 0.70). Baseline risk of MACE and indexes of development status (i.e., Human Development Index, gross domestic product) were independently associated with GLP-1RA efficacy. This study does not suggest any regional heterogeneity of GLP-1RA efficacy in MACE. However, a higher baseline risk and lower development status were associated with a greater benefit of these drugs.

Unveiling the nexus: exploring the influence of terrorism on energy trade in China and the Belt and Road countries

An examination of the scale of energy trade between China and the countries along the Belt and Road, as well as the terrorist activities in these countries from 2008 to 2019, has been conducted in this study. The spatial and temporal evolution law is revealed through the use of exploratory spatial data analysis. The spatial Durbin model is employed to investigate the impacts and spatial spillover effects of terrorist activities along the Belt and Road on China’s energy trade with these countries. The findings of the study are as follows: Spatial clustering is exhibited by the energy scale of China’s imports and exports with countries along the routes and terrorist activities along the routes, with energy imports concentrated in West Asia and North Africa, energy exports concentrated in Southeast Asia, and terrorist activities concentrated in West Asia and North Africa, South Asia, and Central Asia. A negative effect on the scale of China’s energy imports from the countries along the route is exerted by the terrorism index, and a positive spatial spillover effect is present. The number of terrorist activities and deaths have a negative effect on the scale of China’s energy imports from the countries along the route, but there is no spatial spillover effect. The terrorism index does not affect the scale of energy exports from China to countries along the route, but there is a negative spatial spillover effect. There are differences in the spatial spillover effects of the number of terrorist activities and deaths on the scale of China’s energy exports. The level of economic development, liner transportation convenience, and energy exports dependence of the countries along the route also significantly influence China’s energy trade with these countries.

Racial and ethnic differences in second primary lung cancer risk among lung cancer survivors.

Recent therapeutic advances have improved survival among lung cancer (LC) patients, who are now at high risk of second primary lung cancer (SPLC). Hispanics comprise the largest minority in the United States, who have shown a lower LC incidence and mortality than other races, and yet their SPLC risk is poorly understood. We quantified the SPLC incidence patterns among Hispanics vs other races. We used data from the Multiethnic Cohort, a population-based cohort of 5 races (African American, Japanese American, Hispanic, Native Hawaiian, and White), recruited between 1993 and 1996 and followed through 2017. We identified patients diagnosed with initial primary lung cancer (IPLC) and SPLC via linkage to Surveillance, Epidemiology, and End Resultsregistries. We estimated the 10-year cumulative incidence of IPLC (in the entire cohort) and SPLC (among IPLC patients). A standardized incidence ratio (SIR) was calculated as the ratio of SPLC-to-IPLC incidence by race and ethnicity. Among 202 692 participants, 6788 (3.3%) developed IPLC over 3 871 417 person-years. The 10-year cumulative IPLC incidence was lower among Hispanics (0.80%, 0.72 to 0.88) vs Whites (1.67%, 1.56 to 1.78) or Blacks (2.44%, 2.28 to 2.60). However, the 10-year SPLC incidence following IPLC was higher among Hispanics (3.11%, 1.62 to 4.61) vs Whites (2.80%, 1.94 to 3.66) or Blacks (2.29%, 1.48 to 3.10), resulting in a significantly higher SIR for Hispanics (SIR = 8.27, 5.05 to 12.78) vs Whites (SIR = 5.60, 4.11 to 7.45) or Blacks (SIR = 3.48, 2.42 to 4.84; P < .001). Hispanics have a higher SPLC incidence following IPLC than other races, which may be potentially due to better survival after IPLC and extended duration for SPLC development. Continuing surveillance is warranted to reduce racial disparities among LC survivors.

The health behaviors differences among male and female school-age adolescents in the Middle East and North Africa region countries: a meta-analysis of the Global School-based Student Health Survey data.

Understanding gender disparities in adolescent health behaviors is crucial for developing targeted health promotion strategies. This study uses data from the Global School-based Student Health Survey (GSHS) across 17 MENA countries to analyze gender differences in adolescent health behaviors, aiming to provide a comprehensive overview for both boys and girls. This meta-analysis incorporates data from recent years of the GSHS, covering 17 MENA countries. The objective was to assess and compare health behaviors between adolescent girls and boys. A random-effects model was employed to calculate odds ratios for gender comparisons in these behaviors. Statistical analyses and modeling were performed using JAMOVI software. In most MENA countries, boys consumed more vegetables compared to girls. Girls were less likely to frequent fast food establishments (OR = 0.82, 95% CI: 0.69-0.98) and generally exhibited better self-care behaviors. Boys reported a higher prevalence of physical altercations (OR = 2.18, 95% CI: 1.88-2.51) and were more involved in fights (OR = 3.00, 95% CI: 2.46-3.67). Girls were more likely to miss school without permission and were consistently described as kinder and more helpful across various income levels. However, in some countries such as Oman and Tunisia, boys missed school more frequently. There were no significant gender differences in parental oversight of homework or knowledge of students' activities, but girls were reported to have stronger parental relationships and better parental understanding of their problems and free time, with exceptions in Morocco and the Palestinian Territory-Gaza. Boys were more likely to engage in smoking (OR = 3.57, 95% CI: 2.69-4.76) and other substance use. Conversely, girls reported higher levels of physical inactivity and loneliness, but also demonstrated greater kindness and helpfulness in school settings and stronger parental relationships. Policymakers in the MENA region should develop and implement gender-specific interventions targeting key areas such as hygiene practices, physical activity, and substance use. By focusing on these targeted strategies, they can address the distinct health behaviors and needs of both boys and girls. Effective interventions in these areas are crucial for improving overall health outcomes and promoting healthier lifestyles, thereby enhancing adolescent health and well-being across the region.

Mitochondrial DNA of the Arabian Camel Camelus dromedarius.

The Camelidae family, ranging from southwest Asia to north Africa, South America, and Australia, includes key domesticated species adapted to diverse environments. Among these, the Arabian camel (Camelus dromedarius) is vital to the cultural and economic landscape of the Arabian Peninsula. This review explores the mitochondrial DNA of the dromedary camel, focusing on the D-loop region to understand its genetic diversity, maternal inheritance, and evolutionary history. We aim to investigate the unique characteristics of Arabian camel mtDNA, analyze the D-loop for genetic diversity and maternal lineage patterns, and explore the implications of mitochondrial genomic studies for camel domestication and adaptation. Key findings on mtDNA structure and variation highlight significant genetic differences and adaptive traits. The D-loop, essential for mtDNA replication and transcription, reveals extensive polymorphisms and haplotypes, providing insights into dromedary camel domestication and breeding history. Comparative analyses with other camelid species reveal unique genetic signatures in the Arabian camel, reflecting its evolutionary and adaptive pathways. Finally, this review integrates recent advancements in mitochondrial genomics, demonstrating camel genetic diversity and potential applications in conservation and breeding programs. Through comprehensive mitochondrial genome analysis, we aim to enhance the understanding of Camelidae genetics and contribute to the preservation and improvement of these vital animals.

The anatomy of urban regeneration-led gentrification in the middle east and north Africa—A systematic literature review

The anatomy of urban regeneration-led gentrification in the middle east and north Africa—A systematic literature review

Influence of meteorological conditions on the variability of indoor and outdoor particulate matter concentrations in a selected Polish health resort

The article evaluates air pollution by particulate matter (PM) in indoor and outdoor air in one of the Polish health resorts, where children and adults with respiratory diseases are treated. The highest indoor PM concentrations were recorded during the winter season. Therefore, the maximum average daily concentration values in indoor air for the PM10, PM2.5, and PM1 fractions were 50, 42 and 23 µg/m3, respectively. In the case of outdoor air, the highest average daily concentrations of PM2.5 reached a value of 40 µg/m3. The analyses and backward trajectories of episodes of high PM concentrations showed the impact of supra-regional sources and the influx of pollutants from North Africa on the variability of PM concentrations. The correlation between selected meteorological parameters and PM concentrations shows the relationship between PM concentrations and wind speed. For example, the correlation coefficients between PM1(I) and PM1(O) concentrations and wind speed were − 0.8 and − 0.7 respectively. These factors determined episodes of high PM concentrations during winter periods in the outdoor air, which were then transferred to the indoor air. Elevated concentrations in indoor air during summer were also influenced by chimney/gravity ventilation and the appearance of reverse chimney effect.