Normal Transition Research Articles

Rapid crystal growth kinetics of tungsten dendrites under electrostatic levitation state

The rapid crystal growth kinetics of tungsten dendrites within extremely refractory W60Re40 liquid alloy was examined under electrostatic levitation state. Tungsten dendrite growth through two solidification modes was revealed through modulating the active nucleation and spontaneous nucleation within the liquid undercooling range between 145 and 470 K, leading to the displacement of normal peritectic transition by metastable isomorphous solidification. The tungsten dendrites kept the priority growth direction of 〈100〉 and their growth velocity versus undercooling showed a power law function. The liquid alloy would solidify through normal peritectic transition if assisted with active nucleation from bottom Mo electrode.

Mobile impurity probing a two-dimensional superfluid phase transition

The use of atomically sized quantum systems as highly sensitive measuring devices represents an exciting and quickly growing research field. Here, we explore the properties of a quasiparticle formed by a mobile impurity interacting with a two-dimensional fermionic superfluid. The energy of the quasiparticle is shown to be lowered by superfluid pairing as this increases the compressibility of the Fermi gas, thereby making it easier for the impurity to perturb its surroundings. We demonstrate that the fundamentally discontinuous nature of the superfluid to normal phase transition of a two-dimensional system, leads to a rapid increase in the quasiparticle energy around the critical temperature. The magnitude of this increase exhibits a nonmonotonic behavior as a function of the pairing strength with a sizable maximum in the cross-over region, where the spatial extend of the Cooper pairs is comparable to the interparticle spacing. Since the quasiparticle energy is measurable with present experimental techniques, our results illustrate how impurities entangled with their environment can serve as useful probes for non-trivial thermal and quantum correlations.

Numerical Simulation of One-Sided Normal Zone Propagation in Large Helical Device Conductors

The large helical device (LHD) at the National Institute for Fusion Science (NIFS) is the world's largest heliotron-type superconducting magnetic device for nuclear fusion. At the start of the LHD experiment, a phenomenon in which a finite length of the normal zone propagates only to one side, is observed in the region below the rated operating point. The LHD conductor comprises a NbTi/Cu Rutherford conductor, pure aluminum stabilizer, and copper sheath. The aluminum-stabilized conductor is known to exhibit anomalous magnetoresistance due to Hall currents flowing in its cross-section. To simulate the one-sided propagation phenomenon, a quench simulation is performed, considering the Hall effect. A difference is observed in the current-transfer length from the Rutherford conductor to the aluminum stabilizer and copper sheath between the left front and the right front of the normal zone, and the Joule heat in the Rutherford conductor immediately after the normal transition is asymmetric. Under He II cooling (2 K) and a magnetic flux density of 6 T, the one-sided propagation phenomenon is numerically simulated in the transport current range of 15–17 kA. These results are in good agreement with the experimental results.

Microbiome in Critical Care: An Unconventional and Unknown Ally.

The digestive tract represents an interface between the external environment and the body where the interaction of a complex polymicrobial ecology has an important influence on health and disease. The physiological mechanisms that are altered during hospitalization and in the intensive care unit (ICU) contribute to the pathobiota's growth. Intestinal dysbiosis occurs within hours of being admitted to ICU. This may be due to different factors, such as alterations of normal intestinal transit, administration of various medications, or alterations in the intestinal wall, which causes a cascade of events that will lead to the increase of nitrates and decrease of oxygen concentration, and the liberation of free radicals. This work aims to report the latest updates on the microbiota's contribution to developing sepsis in patients in the ICU department. In this short review, the latest scientific findings on the mechanisms of intestinal immune defenses performed both locally and systemically have been reviewed. Additionally, we considered it necessary to review the literature on the basis of the many studies carried out on the microbiota in the critically ill as a prevention to the spread of the infection in these patients. This review has been written to answer four main questions: 1- What are the main intestinal flora's defense mechanisms that help us to prevent the risk of developing systemic diseases? 2- What are the main Systemic Abnormalities of Dysbiosis? 3- What are the Modern Strategies Used in ICU to Prevent the Infection Spreading? 4- What is the Relationship between COVID-19 and Microbiota? We reviewed 72 articles using the combination of following keywords: "microbiota" and "microbiota" and "intensive care", "intensive care" and "gut", "critical illness", "microbiota" and "critical care", "microbiota" and "sepsis", "microbiota" and "infection", and "gastrointestinal immunity" in: Cochrane Controlled Trials Register, Cochrane Library, Medline and Pubmed, Google Scholar, Ovid/Wiley. Moreover, we also consulted the site ClinicalTrials.com to find out studies that have been recently conducted or are currently ongoing. The critical illness can alter intestinal bacterial flora leading to homeostasis disequilibrium. Despite numerous mechanisms, such as epithelial cells with calciform cells that together build a mechanical barrier for pathogenic bacteria, the presence of mucous associated lymphoid tissue (MALT) which stimulates an immune response through the production of interferon-gamma (IFN-y) and THN-a or or from the production of anti-inflammatory cytokines produced by lymphocytes Thelper 2. But these defenses can be altered following hospitalization in ICU and lead to serious complications, such as acute respiratory distress syndrome (ARDS), health care associated pneumonia (HAP) and ventilator associated pneumonia (VAP), systemic infection and multiple organ failure (MOF), but also to the development of coronary artery disease (CAD). In addition, the microbiota has a significant impact on the development of intestinal complications and the severity of the SARS-COVID-19 patients. The microbiota is recognized as one of the important factors that can worsen the clinical conditions of patients who are already very frail in the intensive care unit. At the same time, the microbiota also plays a crucial role in the prevention of ICU-associated complications. By using the resources that are available, such as probiotics, synbiotics or fecal microbiota transplantation (FMT), we can preserve the integrity of the microbiota and the GUT, which will later help maintain homeostasis in ICU patients.

Temperature-sensitive spin-wave nonreciprocity induced by interlayer dipolar coupling in ferromagnet/paramagnet and ferromagnet/superconductor hybrid systems

Spin-wave (SW) spectra have theoretically been studied in a thin film of a ferromagnet (FM) on a substrate from a paramagnet (PM) (an FM above the critical temperature) or from superconductor (SC). A spin wave propagating in the FM induces the dynamic magnetization and superconducting current in the underlying PM and SC, respectively, which affect the SW propagation by their magnetic fields. As a result of this interaction, the SW spectrum becomes nonreciprocal to depend on the sign of the SW wave vector q. We show that the nonreciprocal contribution to the SW spectra in FM/PM and FM/SC systems is given by the frequency shift of {\Delta}{\omega}(q)={\omega}(q)-{\omega}(-q)=a(T)({\tau}{\cdot}q) with {\tau}=(n{\times}M) being the toroidal magnetic moment, M the FM magnetization, n the unit vector normal to the FM/PM(SC) interface, and a(T) the temperature-dependent constant of a dipole nature, whose sign depends on the substrate type. As the {\Delta}{\omega}(T) dependence is strong at temperatures T close to the critical temperature Tc for the FM-PM or normal metal-SC transition, one gets a possibility to control the frequency SW nonreciprocity with temperature variation near Tc. The dipolar mechanism we propose for SW frequency nonreciprocity is promising for introducing this property of SW propagation into functional devices.

Loss of functional heterogeneity along the CA3 transverse axis in aging

Age-related deficits in pattern separation have been postulated to bias the output of hippocampal memory processing toward pattern completion, which can cause deficits in accurate memory retrieval. Although the CA3 region of the hippocampus is often conceptualized as a homogeneous network involved in pattern completion, growing evidence demonstrates a functional gradient in CA3 along the transverse axis, as pattern-separated outputs (dominant in the more proximal CA3) transition to pattern-completed outputs (dominant in the more distal CA3). We examined the neural representations along the CA3 transverse axis in young (Y), aged memory-unimpaired (AU), and aged memory-impaired (AI) rats when different changes were made to the environment. Functional heterogeneity in CA3 was observed in Y and AU rats when the environmental similarity was high (altered cues or altered environment shapes in the same room), with more orthogonalized representations in proximal CA3 than in distal CA3. In contrast, AI rats showed reduced orthogonalization in proximal CA3 but showed normal (i.e., generalized) representations in distal CA3, with little evidence of a functional gradient. Under experimental conditions when the environmental similarity was low (different rooms), representations in proximal and distal CA3 remapped in all rats, showing that CA3 of AI rats is able to encode distinctive representations for inputs with greater dissimilarity. These experiments support the hypotheses that the age-related bias toward hippocampal pattern completion is due to the loss in AI rats of the normal transition from pattern separation to pattern completion along the CA3 transverse axis.

Deep Visual Proteomics defines single-cell identity and heterogeneity

Despite the availabilty of imaging-based and mass-spectrometry-based methods for spatial proteomics, a key challenge remains connecting images with single-cell-resolution protein abundance measurements. Here, we introduce Deep Visual Proteomics (DVP), which combines artificial-intelligence-driven image analysis of cellular phenotypes with automated single-cell or single-nucleus laser microdissection and ultra-high-sensitivity mass spectrometry. DVP links protein abundance to complex cellular or subcellular phenotypes while preserving spatial context. By individually excising nuclei from cell culture, we classified distinct cell states with proteomic profiles defined by known and uncharacterized proteins. In an archived primary melanoma tissue, DVP identified spatially resolved proteome changes as normal melanocytes transition to fully invasive melanoma, revealing pathways that change in a spatial manner as cancer progresses, such as mRNA splicing dysregulation in metastatic vertical growth that coincides with reduced interferon signaling and antigen presentation. The ability of DVP to retain precise spatial proteomic information in the tissue context has implications for the molecular profiling of clinical samples.

The calculation and measurement of electromagnetic energy flows for investigation of critical current estimation for high-temperature superconducting coil by means of pick-up coils

For practical operations of high-temperature superconducting (HTS) devices, we have proposed a monitoring and diagnosing system to detect the degradations of superconducting properties before normal transitions occur locally in the HTS winding. The proposed system estimates the distributions of critical current indirectly from measurement results of the active power components of the Poynting vector around the monitoring HTS devices conducting ac currents by means of pick-up coils pairs mounted surrounding the HTS devices. For this purpose, it is necessary to solve the inverse problem. In order to estimate the critical current distribution, therefore, it is first necessary to be able to calculate the measurement signal distribution from the critical current distribution of the monitoring coil. This paper first proposes the calculation method of signal distributions measured by our system, next reports the results of the experiments and analysis, which were carried out to verify the validity of the calculation method. A pancake coil wound with Bi-2223 multifilamentary tape exposed to a uniform AC magnetic field was assumed as a monitoring coil in the experiments and analyses. The good agreement between the measured signals obtained from the experiments and the numerical analysis demonstrates the effectiveness of the proposed calculation method of measured signals.

Chemical Solution Deposition of Insulating Yttria Nanolayers as Current Flow Diverter in Superconducting GdBa2Cu3O7-δ Coated Conductors.

The primary benefit of a metallic stabilization/shunt in high temperature superconductor (HTS) coated conductors (CCs) is to prevent joule heating damage by providing an alternative path for the current flow during the HTS normal state transition (i.e., quench). However, the shunt presence in combination with unavoidable fluctuations in the critical current (Ic) of the HTS film can develop a localized quench along the CC’s length if the operational current is kept close to Ic. This scenario, also known as the hot-spot regime, can lead to the rupture of the CC if the local quench does not propagate fast enough. The current flow diverter (CFD) is the CC architecture concept that has proven to increase the conductor’s robustness against a hot-spot regime by simply boosting the quench velocity in the CC, which avoids the shunt compromise in some applications. This work investigates a practical manufacturing route for incorporating the CFD architecture in a reel-to-reel system via the preparation of yttrium oxide (Y2O3) as an insulating thin nanolayer (∼100 nm) on top of a GdBa2Cu3O7 (GdBCO) superconductor. Chemical solution deposition (CSD) using ink jet printing (IJP) is shown to be a suitable manufacturing approach. Two sequences of the experimental steps have been investigated, where oxygenation of the GdBCO layer is performed after or before the solution deposition and the Y2O3 nanolayer thermal treatment formation step. A correlated analysis of the microstructure, in situ oxygenation kinetics, and superconducting properties of the Ag/Y2O3/GdBCO trilayer processed under different conditions shows that a new customized functional CC can be prepared. The successful achievement of the CFD effect in the case of the preoxygenated customized CC was confirmed by measuring the current transfer length, thus demonstrating the effectiveness of the CSD-IJP as a processing method.

Synthesis, structural evolution, and dielectric properties of a new perovskite solid solution (Pb0.5Sr0.5)(Zr0.5Ti0.5)O3–PbTiO3

AbstractTo explore lead‐reduced dielectric materials in the SrTiO3–PbTiO3–PbZrO3 ternary system, a novel solid solution between relaxor ferroelectric (Pb0.5Sr0.5)(Zr0.5Ti0.5)O3 and ferroelectric PbTiO3, namely (1 − x)(Pb0.5Sr0.5) (Zr0.5Ti0.5)O3–xPbTiO3 (lead–strontium–zirconate–titanate [PSZT]–PT), has been synthesized in the perovskite structure by high‐temperature solid‐state reaction method in the form of ceramics. The crystal structure and phase symmetry of the materials synthesized were analyzed and resolved based on X‐ray powder diffraction (XRD) data through both the Pawley and Rietveld refinements. The results of the structural refinements indicate that at low PT‐concentration end of the solid solution system, for example, x = 0.05, the PSZT–PT solid solution exhibits a cubic structural symmetry (with the space group Pm‐3m). As the PT concentration (x) increases, the structure of (1 − x)PSZT–xPT gradually transforms from the cubic to a tetragonal (P4mm) phase. In the composition range of x = 0.10–0.25, a mixture of the cubic and tetragonal phases was identified. As the concentration of PT increases, the proportion of the tetragonal phase increases at the expense of the cubic phase. For a composition of x > 0.25, a pure tetragonal phase is observed. The dielectric properties of the materials were studied by measuring the permittivity as a function of temperature at various frequencies. For the composition of x = 0.05, the temperature dependence of dielectric constant shows typical relaxor behavior. For x = 0.35, the dielectric peaks indicate a normal ferroelectric phase transition. Overall, a structural transformation from a central‐symmetric, nonpolar cubic phase to a non‐centrosymmetric, polar tetragonal phase is induced by the substitution of PT for PSZT in the pseudo‐binary solid solution of (1 − x)PSZT–xPT, which also reveals an interesting relaxor to ferroelectric crossover phenomenon.

Electrocardiographic QRS axis shift, rotation and COVİD-19.

In patients with coronavirus disease-2019 (COVID-19), severe dyspnea is the most dramatic complication. Severe respiratory difficulties may include electrocardiographic frontal QRS axis rightward shift (Rws) and clockwise rotation (Cwr). This study investigated the predictability of advanced lung tomography findings with QRS axis shift and rotation. This was a retrospective analysis of 160 patients. Patients were divided into the following two groups: normal (n = 80) and low (n = 80) oxygen saturation. These groups were further divided into four groups according to the rightward and leftward axis shift (Lws) on the electrocardiographic follow-up findings. These groups were compared in terms of electrocardiographic rotation (Cwr, counterclockwise rotation, or normal transition), tomographic stage (CO-RADS5(advanced)/CO-RADS1-4), electrocardiographic intervals, and laboratory findings. In patients with low oxygen saturation, the amount of QRS axis shift, Cwr, and tomographic stage were significantly higher in the Rws group than in the Lws group. There were no differences in the above parameters between the Rws and Lws groups in patients with normal oxygen saturation. Logistic regression analysis revealed that the presence of Cwr and Rws independently increased the risk of CO-RADS5 by 18.9 and 4.6 fold, respectively, in patients with low oxygen saturation. In COVID-19 patients who have dyspnea with low oxygen saturation, electrocardiographically clockwise rotation with a rightward axis shift demonstrated good sensitivity (80% [0.657-0.943]) and specificity (80% [0.552->1]) for predicting advanced lung tomographic findings. NCT04698083.

Spinodal strain glass in Mn-Cu alloys

Strain glasses (STGs), which are characterized by nanodomains of martensite formed via a strain glass transition, can produce many unusual properties not possessed by normal martensitic alloys. These nanodomains originate from the formation of short-range strain ordering by the disruption of otherwise long-range strain ordering or normal martensitic transformation through sufficient atomic/nanoscale random stress/strain field. So far the atomic/nanoscale randomness is known to be from either point defects, dislocations, or nanoprecipitates. Here we report a spinodal STG alloy Mn60Cu40, which stems from nanoscale composition modulations (5-20 nm) formed in the early stage of spinodal decomposition, which is identified by STEM-EDS and HRTEM. For short-time (<50 min) aged sample, a strain glass transition was identified by its typical signatures including invariance of global face-centered cubic (fcc) structure with cooling, frequency dependence of elastic moduli at STG transition temperature (Tg) following a Vogel-Fulcher relationship, non-ergodicity as manifested by zero-field-colling/field-cooling curves, and the formation of martensitic face-centered tetragonal (fct) nanodomains. For long-time (≥50 min) aged sample, a normal martensitic transition from fcc to fct appears with cooling, being consistent with literatures. As the result, a temperature vs. aging-time phase diagram of spinodal STG was established and shows a crossover from STG to martensite above a critical aging time. The spinodal STG exhibits a non-magnetic Elinvar behavior, i.e., nearly constant elastic modulus over a wide temperature range, together with high-damping capacity. We anticipate that the spinodal STG and associated novel properties may also be found in other metallic and ceramic spinodal materials.

Observation of a Jump-Like Transition from Fast to Normal Kinetics of Facets for Free-Growing Helium Crystals

The growth kinetics is studied of free-growing helium crystals within the temperature range 0.5-0.83 K and supersaturations to 10 mbar. For the pressure supersaturations above 0.5 mbar, numerous drastic changes are observed in the growth kinetics for all crystalline facets from the normal and slow kinetics to the anomalously high or burst-like one. It is found for the first time that the anomalous to normal transition in the facet growth kinetics occurs in a jump like manner within a time 80 {\mu}s interval of the measurement record.

Aberrant RET expression affects normal mammary gland post-lactation transition, enhancing cancer potential.

ABSTRACTRET is a receptor tyrosine kinase with oncogenic potential in the mammary epithelium. Several receptors with oncogenic activity in the breast are known to participate in specific developmental stages. We found that RET is differentially expressed during mouse mammary gland development: RET is present in lactation and its expression dramatically decreases in involution, the period during which the lactating gland returns to a quiescent state after weaning. Based on epidemiological and pre-clinical findings, involution has been described as tumor promoting. Using the Ret/MTB doxycycline-inducible mouse transgenic system, we show that sustained expression of RET in the mammary epithelium during the post-lactation transition to involution is accompanied by alterations in tissue remodeling and an enhancement of cancer potential. Following constitutive Ret expression, we observed a significant increase in neoplastic lesions in the post-involuting versus the virgin mammary gland. Furthermore, we show that abnormal RET overexpression during lactation promotes factors that prime involution, including premature activation of Stat3 signaling and, using RNA sequencing, an acute-phase inflammatory signature. Our results demonstrate that RET overexpression negatively affects the normal post-lactation transition.

MANAJEMEN ASUHAN KEBIDANAN SEGERA BAYI BARU LAHIR BERKELANJUTAN PADA BAYI NY “M” DENGAN IKTERUS NEONATORUM FISIOLOGIS DI RUMAH SAKIT UMUM BAHAGIA MAKASSAR TAHUN 2021

Introduction Neonatal jaundice is a clinical condition in infants characterized by a yellow discoloration of the skin and sclera due to excessive accumulation of unconjugated bilirubin. There were about 60% of term infants who experience jaundice in the first week of their age, and about 80% of cases were found in preterm infants. Neontaol jaundice in newborns was a common problem often faced by health workers. The increase level of bilirubin in newborns has been considered to be a normal transition phase. However, the excessive increase of bilirubin in blood can cause a janudice which requires a special treatment. The major purpose of this research was to investigate and conduct a midwifery care management on a newborn of Mrs. “M” with the case of physiological jaundice at Bahagia General Hospital of Makassar. This research was conducted on October 8 to November 21, 2021, and this study was based on the 7 stages of Varney management approach and SOAP documentation procedure. The findings of this study indicated that there were no obstacles found during the process of treatment on the newborn of Mrs. “M”. The treatments and care were conducted for five times for approaximately 1 month. During the process, it was found that the newborn had undergone a jaundice on his skin since october 7, 2021. However, on the third visit, it was apparent that the infant’s condition was better in which the bilirubin level saw a considerable fall. As a result, the treatment of phototheraphy could be discontinued. This study concluded that the newborn’s condition had been good due to the quick and proper treatment and care given to the baby. In this case, the roles of mifwives and health workers are highly significant to deal with patients with the case of neonatal jaundice. Moreover, it is also expected to midwives to give proper understanding and information to the families on the patient so that they could help in the healing process of the baby.

Reversible transition from ferrofluid drop to spikes due to an approaching magnet

Remarkably, we experimentally evidenced normal field instability-driven reversible transition from ferrofluid droplet to spikes, when a sessile ferrofluid drop is exposed to a varying magnetic field gradient due to an approaching magnet, without flipping its direction of motion. We find the reversible transition is attributed to the critical magnetization of the ferrofluid and a characteristic wavelength that control normal-field instability. We extend the theory of magnetic instability by including non-uniformity in the magnetic field in all directions to predict the critical condition for transition, which is in good agreement with experiments. The spacing between spikes and spike height, and the number of spikes measured from experiments are in agreement with existing theory.

Segmental pairs of dermal secretory cells release proteins into the hemolymph at the larval-pupal molt

At each molt of Manduca, the large dermal secretory cells expel the protein contents of their vacuoles into the hemocoel. The constellation of proteins expelled at the last larval-pupal molt, however, differs qualitatively from those proteins released at earlier larval-larval molts. Secretory cells at the two stages not only have different lectin staining properties but also have different proteins that separate on two-dimensional gels. Numerous physiological changes accompany the termination of the last larval instar, including increased chitin synthesis, diminished oxygen delivery, and reduced humoral immunity. Secretion of trehalase that is essential for chitin synthesis and the release of hypoxia up-regulated protein to ameliorate oxygen deprivation help ensure normal transition from larva to pupa. Proteins released by dermal secretory cells at this last molt could supplement the diminished immune defenses mediated by fat body and hemocytes at the end of larval life. Additional immune defenses provided by dermal secretory cells could help ensure a safe transition during a period of increased vulnerability for the newly molted pupa with its soft, thin cuticle and reduced mobility.

Thermal Transitions in Dense Two-Colour QCD

The infamous sign problem makes it impossible to probe dense (baryon density μB &gt; 0) QCD at temperatures near or below the deconfinement threshold. As a workaround, one can explore QCD-like theories such as twocolour QCD (QC2D) which don’t suffer from this sign problem but are qualitively similar to real QCD. Previous studies on smaller lattice volumes have investigated deconfinement and colour superfluid to normal matter transitions. In this study we look at a larger lattice volume Ns = 24 in an attempt to disentangle finite volume and finite temperature effects. We also fit to a larger number of diquark sources to better allow for extrapolation to zero diquark source.

Pelviureteric Junction Obstruction Due to Vascular Anomalies in Children - Simple Surgical Options.

ABSTRACTAims:Pelviureteric junction obstruction (PUJO) due to aberrant lower polar artery is conventionally managed with pyeloplasty. We present our experience of managing PUJO due to “vascular” anomalies-aberrant lower polar artery and vascular adhesions with simpler surgical options.Subjects and Methods:This is a protocol based, retrospective study of PUJO. Preoperative investigations included ultrasonography (USG) and diuretic renogram. An intraoperative methylene blue test (MBT) assessed transit across the Pelviureteric junction (PUJ) after release of vascular compression. Surgical management included adhesiolysis for vascular adhesions and pyelopyelostomy anterior to the aberrant polar artery. Postoperative studies were repeated after 3 and 6 months.Results:Fourteen of 144 PUJO (9.7%) were “vascular” obstructions. Those with vascular adhesions (six) were largely infants with antenatal hydronephrosis. Children with aberrant lower polar artery (eight) were older, had fleeting symptoms, minimally increased pelvic diameter and subtle impairment on diuretic renogram. Majority were term males with urinary tract infection. The MBT showed normal transit across the PUJ in all. Postoperatively, there was progressive improvement on USG and diuretic renogram after 3 and 6 months. None had any complication or redosurgeries. At a mean follow-up of 41.2 months, all are asymptomatic.Conclusions:PUJO due to extrinsic vascular anomalies is rare. Intraoperative evaluation with the MBT ruled out associated intrinsic pathology. We describe two simple surgical alternatives preserving the normal PUJ - adhesiolysis for vascular adhesions and pyelopyelostomy for aberrant lower polar artery. The preliminary outcomes are comparable to conventional pyeloplasty.

THE DYSPHAGIA INVESTIGATION: IS THERE STILL SPACE FOR THE VIDEOFLUOROSCOPIC METHOD?

ABSTRACT - BACKGROUND:Dysphagia can lead to aspiration pneumonia, impacting the nutritional status and quality of life of the patient. The videofluoroscopy is highlighted for allowing both a real-time evaluation and the recording of the images for later review and analysis.AIM: This study aimed to describe the characteristics of the population referred for videofluoroscopy and its value as an investigation method.METHODS: A descriptive and retrospective study was conducted. Exams were analyzed in lateral and anteroposterior views and reviewed using the frame-by-frame analysis software. The variables analyzed were an indication of the exam, previous diseases, dynamics of the oral and pharyngeal phases, and the degree of penetration/aspiration.RESULTS: A total of 141 exams were analyzed. The study population had a median age of 66.24±17.78 years. For the indication of the exam, the investigation of dysphagia was highlighted (n=87, 61.7%) and for previous conditions, diverticulum (n=13, 9.2%), pharyngeal bar (n=12, 8.51%), and stroke and Parkinson’s disease (n=9, 6.4%) were highlighted. In the oral phase, 45 (31.9%) patients had a premature loss, and 108 (76.6%) patients had normal transit time. However, 100 (70.9%) had inadequate ejection. In the pharyngeal phase, 119 (84.4%) had efficient laryngeal displacement and 107 (75.9%) had an adequate opening of the upper esophageal sphincter. The beginning of the pharyngeal phase was classified as inadequate in 131 (92.9%) patients, and 80 (56.74%) had pharyngeal residue. Notably, 100 (70.9%) patients had grade 1 on the penetration/aspiration scale.CONCLUSION: Despite the didactic division of phases, swallowing is complex and has transition stages. Videofluoroscopy is the only method for evaluating all phases of swallowing and its events.