Being assertive helps the nursing students to control and handle stressful situations in a healthy manner which boosts their personal power, self confidence and self esteem. The study aimed at assessing the assertiveness, self-esteem and stress among nursing students. Quantitative Non experimental descriptive design was used for the study. Non probability purposive sampling was used to select 64 subjects for the study. Majority 98% of the study subjects were somewhat assertive, 64% had normal self-esteem, 69% had moderate stress and 25% had severe stress. There was a significant difference in the assertiveness between first and the second year with a mean difference of 11.556 at p<0.05. There was a significant difference in the self-esteem between first and third year with a mean difference of 2.732, and between the first year and internship with a mean difference of 3.160 at p<0.05. There was no significant difference in stress between the groups.