Normal Hemoglobin Levels Research Articles

Effect of Hemoglobin Levels on the Process of Healing Post Sectio Caesarea Wounds

The long healing of post sectio caesarea wounds has an impact on patients and their families.In addition to the additional burdensome costs, patients can experience trauma due to the wound healing process that lasts a long time.Hemoglobin is the main component that transports oxygen and nutrients needed for the wound healing process. This study aims to analyze the effect of hemoglobin levels on the healing process of post sectio caesarea wounds at Aminah Hospital Blitar.The research design uses a case control approach samples were taken using consecutive sampling techniques with research inclusion criteria of 89 respondents.Data on hemoglobin levels were taken from secondary data on preoperative hemoglobin levels of patients in medical record documents and data on the process of wound healing seen from the results of one-time observation when the patient controls the obstetric polyclinic between day 7 to day 10 post sectio caesarea.Data were analyzed using a simple linear regression test. The results showed that 62.9% of respondents had normal hemoglobin levels and 79.77% of respondents showed good wound healing processes.The results of the statistical test analysis showed a p value of 0.000 which was smaller than α of 0.05 with an R-square of 0.196.This means that there is an effect of hemoglobin levels on the wound healing process post sectio caesarea.So it is expected that pregnant women and their families pay attention to the value of hemoglobin levels during pregnancy and after delivery to ensure health and wound healing post sectio caesarea.Keywords:hemoglobin,wound,post sectio caesarea

Unlocking the mystery of the role of Vitamin D in iron deficiency anemia in antenatal women: a case control study in a tertiary care hospital in New Delhi

BackgroundVitamin D deficiency and anemia are clinical conditions that coexist during pregnancy. A high prevalence of Vitamin D deficiency ranging from 50 to 94% is seen throughout the country. The aim of the study was to discover the association between Vitamin D status and iron deficiency anemia during pregnancy. Improving the vitamin D status of pregnant women is crucial to prevent iron deficiency anemia and can improve maternal and fetal outcomes.MethodsA case–control study including 94 primigravida women of age within the age group 18 to 30 years, divided into two groups: a Case Group of 48 patients with already diagnosed iron deficiency anemia (mild to moderate) and a Control Group of 46 antenatal women with normal hemoglobin levels. Data on sociodemographic, clinical characteristics, and the levels of 25(OH) Vitamin D was estimated in both the groups. The association of 25(OH)D levels and anemia was then determined using suitable statistical analysis.ResultsAmong pregnant women affected with anemia, 75% of women had serum Vitamin D concentrations < 20 ng/ml compared to 52.2% of women in the controls. Maternal serum vitamin D level was significantly lower in pregnant women affected with anemia (19.61 ± 13.12) as compared to control (29.43 ± 24.05); (p = 0.024). A positive correlation was found between hemoglobin and vitamin D levels in pregnant women (Pearson’s r = 0.200, p = 0.05).ConclusionsThese findings provide evidence suggesting that Vitamin D deficiency or insufficiency during pregnancy may be a risk factor for anemia and correction of Vitamin D levels can improve hemoglobin levels. Educational efforts should be made to include safe vitamin D intake in antenatal care.

Association of Periprocedural Haemoglobin Reduction and Myocardial Injury in Patients with Unstable Angina Undergoing Percutaneous Coronary Intervention

Background: Patients undergoing percutaneous coronary intervention are at risk of different complications such as periprocedural bleeding and acute hemoglobin reduction that can lead to myocardial injury. Blood loss through the catheter during the procedure and through puncture site haematoma causes periprocedural acute haemoglobin drop. Objectives: To find out the association between acute haemoglobin reduction and myocardial injury after PCI in patients with unstable angina. Methods: This prospective observational study was conducted at the National Institute of Cardiovascular Diseases (NICVD) for one year of time. A total of 130 patients were enrolled based on inclusion and exclusion criteria during the study period. Haemoglobin and troponin-I were measured before and after PCI within 24 to 48 hours of the procedure. On the basis of post-procedural acute haemoglobin level, the study population was categorized into two groups: Group I patients with normal haemoglobin levels and Group II patients with significant acute haemoglobin reduction (≥ 1 gm/dl). Results: A total of 24 patients developed a periprocedural myocardial injury, among them 17 (70.8%) were in the reduced haemoglobin group and 7 (29.2%) in the normal haemoglobin group. Elevation of troponin I after PCI was higher in group II than in group I patients with a statistically significant difference. Multivariate logistic regression analysis showed that haemoglobin reduction was an independent predictor of PMI (OR 1.94; 95% CI, 1.241-8.684; p = 0.01). Conclusion: Periprocedural haemoglobin reduction in patients with unstable angina was associated with myocardial injury after percutaneous coronary intervention (PCI).

Replenishment of iron deficiency in women before the use of assisted reproductive technologies

Introduction. Anemia is a major health problem worldwide, increasing the risks of low birth weight, preterm birth, perinatal mortality, stillbirth, postpartum hemorrhage, and maternal mortality. Replenishing iron deficiency at the stage of preconceptional preparation reduces the incidence of IDA and can reduce the incidence of pregnancy complications and improve perinatal outcomes.Aim. To evaluate the effectiveness of ferrous sulfate 80 mg and its potential to replenish iron deficiency in women with infertility before using assisted reproductive technologies (ART).Materials and methods. A prospective clinical longitudinal study was conducted from May to September 2023 at LLC Health Clinic, Moscow. The study included women (n = 34) at the stage of pregnancy planning by IVF with a diagnosed iron deficiency. Iron deficiency was established in accordance with the following criteria: decrease in serum ferritin level less than 30 μg/l, serum iron level less than 15 μmol/l.Results. After 12 weeks of taking ferrous sulfate, the average hemoglobin level increased from 112.3 ± 6.5 (101–119) g/l to 118.5 ± 6.5 (110–133) g/l (W-Wilcoxon 9300 test, p = 0.003), mean serum iron level from 15.4 ± 4.0 (5.7–22.5) μmol/l to 34.8 ± 7.1 (20.1–46.7) μmol/l (Wilcoxon W test 602.0, p &lt; 0.001), mean ferritin level from 8.2 ± 3.1 (4.5–17.0) μg/ml to 37.6 ± 6.7 (30.6–52.6) μg/ml (Wilcoxon W test 595.0, p &lt; 0.001).Conclusions. Timely examination of patients for iron deficiency and iron deficiency anemia at the stage of preconceptional preparation makes it possible to prescribe an effective correction, thereby helping to reduce the risks of complications of pregnancy and childbirth.

Cerebral hemodynamics and oxygenation in adult patients with sickle cell disease after stem cell transplantation.

Sickle cell disease (SCD) is characterized by chronic hemolytic anemia associated with impaired cerebral hemodynamics and oxygen metabolism. Hematopoietic stem cell transplantation (HSCT) is currently the only curative treatment for patients with SCD. Whereas normalization of hemoglobin levels and hemolysis markers has been reported after HSCT, its effects on cerebral perfusion and oxygenation in adult SCD patients remain largely unexplored. This study investigated the effects of HSCT on cerebral blood flow (CBF), oxygen delivery, cerebrovascular reserve (CVR), oxygen extraction fraction (OEF), and cerebral metabolic rate of oxygen (CMRO2 ) in 17 adult SCD patients (mean age: 25.0 ± 8.0, 6 females) before and after HSCT and 10 healthy ethnicity-matched controls (mean age: 28.0 ± 8.8, 6 females) using MRI. For the CVR assessment, perfusion scans were performed before and after acetazolamide as a vasodilatory stimulus. Following HSCT, gray and white matter (GM and WM) CBF decreased (p < .01), while GM and WM CVR increased (p < .01) compared with the baseline measures. OEF and CMRO2 also increased towards levels in healthy controls (p < .01). The normalization of cerebral perfusion and oxygen metabolism corresponded with a significant increase in hemoglobin levels and decreases in reticulocytes, total bilirubin, and LDH as markers of hemolysis (p < .01). This study shows that HSCT results in the normalization of cerebral perfusion and oxygen metabolism, even in adult patients with SCD. Future follow-up MRI scans will determine whether the observed normalization of cerebral hemodynamics and oxygen metabolism prevents new silent cerebral infarcts.

Nutrition Education Using E-Booklet Against Hemoglobin Levels of Young Women

Anemia in adolescent girls is characterized by Hb levels &lt; 12 g / dl. Anemia is influenced by various factors including nutritional intake, and knowledge. Anemia results in learning concentration, fatigue, to decreased learning achievement. One of them overcomes this problem by giving Fe supplements and nutrition education. The purpose of this study was to determine the relationship between nutrition education using e-booklets on hemoglobin levels in adolescent girls. The design of this study was a Quasi-Experiment with a comparison group. The study was divided into the treatment group and the comparison group. Providing nutrition education using e-booklets and Fe supplements for 3 weeks in the treatment group. The number of respondents was 36 in the treatment group and the comparison in the comparison group. The results of the t-dependent test showed an average difference in the two groups with a p-value of  0.05. The average hemoglobin level of the treatment group was 0.411 g / dl and the comparison group was 0.2 g / dl. The results of the t-independent test showed no difference in the average hemoglobin levels of the treatment group with a comparison group with a p-value of  0.05. The average difference in hemoglobin levels in the treatment group with the comparison group was 0.211 g / dl. Fe supplements and nutrition education with e-booklets can increase Hb levels.

THU601 Massive Pericardial Effusion As Sole Symptom For Uncontrolled Hypothyroidism.

Abstract Disclosure: D.A. Lopez: None. M. Caban: None. C. Camacho: None. Y. Fuentes: None. M. Sanchez: None. K. Velez: None. Hypothyroidism is a common endocrine disorder with worldwide prevalence resulting from deficiency of thyroid hormone that can affect multiple organs. It can be asymptomatic and subclinical or symptomatic with fatal complications. Hypothyroidism can present with symptoms such as fatigue, slow movement and slow speech, cold intolerance, constipation, weight gain, and bradycardia. Hypothyroidism can be the cause of pericardial effusion due to increase membrane permeability. Massive pericardial effusion or pericardial tamponade is rare. Pericardial effusion can also be caused by autoimmune conditions, infections, uremia, medications, iatrogenic, and trauma. This is a case of 68-year-old Hispanic female with past medical history of hypothyroidism that was admitted to the hospital due to large pericardial effusion. These findings were found incidentally by her primary care physician during a preoperative evaluation for cataract surgery. Chest X-ray showed massive enlargement of the cardiac silhouette. Echocardiogram was ordered presenting large circumferential pericardial effusion with moderate diastolic right atrial collapse reason why patient was sent to the hospital. Physical examination showed distant heart sounds but absent jugular venous distention. Vital signs were within normal limits. Beck's triad was absent. Electrocardiogram showed a sinus rhythm with low QRS voltage. Patient denied any recent procedure, trauma, myocardial infarction, malignancy, or fever. Complete blood count was without leukocytosis, normal hemoglobin levels and platelet count. Basic metabolic panel presented without electrolyte disturbances and preserved renal function. Evaluation for causes of pericardial effusion was made including autoimmune conditions. Results showed negative ANA, Rheumatoid factor, Anti-dsDNA antibody, Anti-Scl-70 antibody, anti-U1-ribonucleoprotein, anti-Ro, and anti-La. Inflammatory markers were within normal limits. TSH level were in 22.5μIU/mL (0.03-5.0μIU/mL) with undetectable Free T4 pointing towards uncontrolled hypothyroidism as the cause of her large pericardial effusion. Patient denied other symptoms of hypothyroidism. She agreed not being compliant with levothyroxine. Pericardiocentesis was done and 750ml of pericardial fluid was removed. A catheter was placed and 200ml of fluid was drained on the second day. Catheter was removed and Echocardiogram showed immediate resolution of the diastolic right atrial collapse. She was sent home with adequate medical therapy and intense education of hypothyroidism. As a take home message, this unique case presents the importance of being compliant to medical therapy since the initial presentation of uncontrolled hypothyroidism could be a fatal complication as pericardial effusion. This could’ve been prevented if compliance with medications was encourage since the beginning of this disorder. Presentation: Thursday, June 15, 2023

Laboratory, clinical, neurological and neuropsychological features of the course of post-COVID syndrome in patients with cerebrovascular disease

A review of the literature reveals a wide range of terms for conditions after coronavirus disease (COVID-19): post-­COVID syndrome, post-acute COVID syndrome, chronic COVID-19, long-term complications of COVID-19, long COVID-19, and post-acute sequelae of severe acute respiratory syndrome coronavirus 2 infection. All these terms and others indicate that after ­COVID-19, a person does not return to his/her usual state of health. Many scientists are researching and looking for the causes of these symptoms, why and when they occur, and how to diagnose and treat them. Therefore, the aim of the study was to improve the diagnosis of post-COVID syndrome in patients with cerebrovascular disease (CVD) by studying clinical, neurological, laboratory and neuropsychological markers. Materials and methods. The study uses psychometric methods — Beck Anxiety Inventory, Hamilton Depression Rating Scale, Fatigue Assessment Scale; neuropsychological — Montreal Cognitive Assessment; clinical — neurological status; laboratory — hemoglobin, C-reactive protein, fibrinogen, albumin, ferritin, lactate dehydrogenase. All patients were divided into four groups: the first group included 20 people with post-­COVID syndrome and CVD, the second — 15 individuals with post-COVID syndrome without CVD, the third — 15 patients without post-COVID syndrome with CVD, and the fourth — 15 people without post-COVID syndrome and without CVD. Results. In the group of patients with post-COVID syndrome with cerebrovascular disease (n1 = 20), the average level of hemoglobin (M = 115.15 ± 4.93) and albumin (M = 32.15 ± 1.53) was below the normal range; the content of fibrinogen (M = 6.04 ± 0.82), C-reactive protein (M = 5.50 ± 0.68) was above normal. Data of the Hamilton Depression Rating Scale indicate that patients with post-COVID syndrome and cerebrovascular disease Data of the Hamilton Depression Rating Scale indicate that patients with post-COVID syndrome and cerebrovascular disease (n1 = 20) had a mild depression (M = 6.75 ± 3.90; M = 8.60 ± ± 3.06). Correlation analysis revealed a direct relationship between cognitive functions and hemoglobin (r = 0.455, p ≤ 0.01), albumin (r = 0.571, p ≤ 0.01) and an inverse relationship between cognitive functions and fibrinogen (r = –0.605, p ≤ 0.01), C-reactive protein (r = –0.547, p ≤ 0.01), ferritin (r = 0.408, p ≤ 0.01). There was an inverse correlation between anxiety and hemoglobin (r = –0.619, p ≤ 0.01) and albumin (r = –0.567, p ≤ 0.01) and a direct relationship between anxiety and fibrinogen (r = 0.550, p ≤ 0.01) and C-reactive protein (r = 0.537, p ≤ 0.01). The depression scale negatively correlates with the level of hemoglobin (r = –0.597, p ≤ 0.01), albumin (r = –0.543, p ≤ 0.01) and directly with the content of fibrinogen (r = 0.433, p ≤ 0.01), C-reactive protein (r = 0.383, p ≤ 0.01) and lactate dehydrogenase (r = 0.276, p ≤ 0.05). The indicators of fibrinogen, C-reactive protein, and ferritin were the highest in the group of patients with post-COVID syndrome and cerebrovascular disease. According to the obtained data, there are statistically significant differences between four groups in cognitive functions (χ2 = 36.419, p ≤ 0.01), fatigue (χ2 = 37.251, p ≤ 0.01), anxiety (χ2 = 37.981, p ≤ 0.01) and depression (χ2 = 37.171, p ≤ 0.01). The highest rate of fatigue, anxiety, and depression was found in patients with post-COVID syndrome and cerebrovascular disease.

Fish-Based Complementary Feeding Practices Increasing Macro and Micro Nutrient Intake And Hemoglobin Levels in Anemia Toddlers

Iron deficiency anemia in toddlers can be prevented by introducing complementary foods alongside breastfeeding. Fish, rich in protein and iron, offers a valuable nutritional source for young children, but proper processing is crucial. This research investigated the impact of fish-based complementary food processing practices (known as MP-ASI in Indonesia) on the nutritional intake and hemoglobin levels of children under five in Tiro District, Pidie Regency. Using a quasi-experimental design, this study involved 40 toddlers from the stunting-prone area of Tiro District, Pidie Regency, along with their mothers as respondents. The toddlers, aged 12-36 months without severe illnesses, were included in the study. The intervention comprised educating and practicing complementary food processing. Before-and-after intervention comparisons showed significant improvements in energy, carbohydrate, protein, zinc, and iron intake levels. Additionally, there was a notable increase in the average hemoglobin (Hb) level, rising by 1.06 g/dl after one month of fish-based complementary food processing intervention. In summary, this intervention effectively enhanced the nutritional quality of children's intake and increased their hemoglobin levels, contributing to the prevention of iron deficiency anemia in toddlers.

Pengaruh Pemberian Jus Umbi Bit terhadap Kadar Hemoglobin Ibu Hamil Trimester III

WHO data (2020), it estimated that worldwide around 32 million pregnant women have anemia. In Indonesia, the incidence of anemia in pregnant women increased in 2018 by 48.8% when compared to 2013, which was 37.1%. Garut Regency in 2019 the prevalence of pregnant women with anemia was 6669 people. Karangpawitan Health Center in 2021, out of 834 pregnant women, 31.5% experienced anemia in the first trimester and as many as 168 pregnant women in third trimester (20.1%). Non-pharmacologically the treatment and prevention of anemia is by consuming green vegetables, nuts, chicken liver, beet tubers, red guava fruit and others. The content of beet tubers in the list of food ingredients includes 108 mg of folic acid, 27.0 mg of calcium, 43.0 mg of phosphorus, 43 mg of vitamin C, 23 mg of magnesium, 9.6 mg of carbohydrates, 1.0 mg of iron (Ministry of Health RI, 2016). Folic acid is very good to help the formation of the baby's brain and overcome the problem of anemia. The purpose of the study was to determine the effect of beetroot juice on hemoglobin levels of pregnant women in the third trimester at Karangpawitan Public Health Center, Garut Regency. The methodology of this research uses Pre test - Post test with control group design. The population in the study were all pregnant women in the third trimester as many as 129 people The samples in this study were TM III pregnant women who experienced mild anemia using purposive sampling as many as 30 people who were divided into 2 groups, namely 15 people in the experimental group and 15 people in the control group. The instruments used are observation sheets and technical instructions for beetroot juice. Data analysis used Paired T-test and Independent Samples Test. The results of the study the average hemoglobin level in the experimental group before being given beet juice was 9.160 and after beet juice was 10.807, while in the control group before the intervention was 8.933 and after the intervention was 9.813. The bivariate results showed a p-value of 0.000 &lt;0.05. The conclusion is that there is an effect of giving beetroot juice + Fe tablets on hemoglobin levels of pregnant women in the third trimester at Karangpawitan Health Center, Garut Regency In 2023. With this study, consumption of beet root juice can be an alternative in increasing hemoglobin levels in pregnant women.

Hospital-Acquired Anemia in Patients with Acute Coronary Syndrome: Epidemiology and Potential Impact on Long-Term Outcome

BackgroundAnemia (either pre-existing or hospital-acquired) is considered an independent predictor of mortality in acute coronary syndromes. However, it is still not clear whether anemia should be considered as a marker of worse health status or a therapeutic target. We sought to investigate the relationship between hospital-acquired anemia and clinical and laboratory findings and to assess the association with mortality and major cardiovascular events at long-term follow-up. MethodsPatients consecutively admitted at Niguarda Hospital between February 2014 and November 2020 for an acute coronary syndrome were included in this cohort analysis and classified as anemic at admission (group A), with normal hemoglobin at admission but developing anemia during hospitalization (hospital-acquired anemia) (group B); and with normal hemoglobin levels throughout admission (group C). ResultsAmong 1294 patients included, group A included 353 (27%) patients, group B 468 (36%), and group C 473 patients (37%). In terms of cardiovascular burden and incidence of death, major cardiovascular events and bleeding at 4.9-year median follow-up, group B had an intermediate risk profile as compared with A and C. Baseline anemia was an independent predictor of death (hazard ratio 1.51; 95% confidence interval, 1.02-2.25; P = .04) along with frailty, Charlson comorbidity Index, estimated glomerular filtration rate, previous myocardial infarction, and left ventricular ejection fraction. Conversely, hospital-acquired anemia was not associated with increased mortality (hazard ratio 1.18; 95% confidence interval, 0.8-1.75; P = .4). ConclusionsHospital-acquired anemia affects one-third of patients hospitalized for acute coronary syndrome and is associated with age, frailty, and comorbidity burden, but was not found to be an independent predictor of long-term mortality.

Outcome of Second Primary Malignancies Developing in Multiple Myeloma Patients.

There is an increased risk of second primary malignancies (SMPs) in patients with multiple myeloma (MM). This multinational 'real-world' retrospective study analyzed the characteristics and outcomes of MM patients that developed SPMs. 165 patients were analyzed: 62.4% males; 8.5% with a prior cancer; 113 with solid SPMs, mainly ≥stage 2; and 52 with hematological SPM (hemato-SPM), mainly MDS/AML. Patients with hemato-SPM were younger (p = 0.05) and more frequently had a prior AutoHCT (p = 0.012). The time to SPM was shorter in the older (>65 years) and more heavily pretreated patients. One hundred patients were actively treated at the time of SPM detection. Treatment was discontinued in 52, substituted with another anti-MM therapy in 15, and continued in 33 patients. Treatment discontinuation was predominant in the patients diagnosed with hemato-SPM (76%). The median OS following SPM detection was 8.5 months, and the main cause of death was SPM. A poor ECOG status predicted a shorter OS (PS 3 vs. 0, HR = 5.74, 2.32-14.21, p < 0.001), whereas a normal hemoglobin level (HR = 0.43, 0.19-0.95, p = 0.037) predicted longer OS. With the continuing improvement in OS, a higher proportion of MM patients might develop SPM. The OS following SPM diagnosis is poor; hence, frequent surveillance and early detection are imperative to improve outcomes.

Pengaruh Pemberian Jus Buah Bit Terhadap Peningkatan Kadar Hemoglobin Pada Remaja Putri Dengan Anemia

Anemia occurs when the hemoglobin level is less than normal or the level of red blood cells in the blood decreases. The beetroot betacyanin pigment is known as trimethyl glycine and is widely used as a radical scavenger, protection against disorders caused by oxidative stress (antioxidant), producing cells including red blood cells. So beetroot juice can be used as a non-pharmacological alternative in preventing anemia. This study aims to determine the effect of giving beetroot juice on increasing hemoglobin levels in young women with anemia at Darul Ihsan Muhammadiyah Sragen Middle School. The type of research used is quantitative research methods. The research design used was experimental with a one group pretest – posttest design approach. The sampling technique used simple random sampling, namely 21 anemic teenage girls at Darul Ihsan Muhammadiyah Sragen Middle School. Bivariate analysis used the Wilcoxon Signed Rank Test using SPSS 26 for windows processing. The research showed that the average hemoglobin level before treatment was 11.414 g/dL and the average hemoglobin level after treatment was 11.757 g/dL or an average increase of 0.343 gdL. The result was p = 0.001 (Pvalue &lt; 0.05) p-value. There is an effect of giving beetroot juice on increasing hemoglobin levels in adolescent girls suffering from anemia at Darul Ihsan Muhammadiyah Sragen Middle School.

The Relationship between Protein Intake and Hemoglobin Levels in Women of Reproductive Age at Inche Abdoel Moeis Hospital Samarinda

The prevalence of anemia in Indonesia among women of childbearing age in 2018 was 28.7%. Less protein intake will inhibit the formation of hemoglobin levels. The purpose of this study was to determine the relationship between protein intake and hemoglobin levels in inpatients of women of childbearing age. The population is 87 and the sample is 38 subjects. Samples were taken by purposive sampling using inclusion and exclusion criteria. The statistical test uses the Spearman test. The results show that protein intake and hemoglobin levels have a value of r = 0.81+, p = 0.00 meaning that there is a significant relationship between protein intake and hemoglobin levels with a very strong relationship strength. Inpatients, especially women of childbearing age, are expected to increase protein intake according with the need for both animal and plant origin to maintain normal hemoglobin levels.

Soluble Transferrin Receptor as Iron Deficiency Biomarker: Impact on Exercise Capacity in Heart Failure Patients.

The soluble transferrin receptor (sTfR) is a marker of tissue iron status, which could indicate an increased iron demand at the tissue level. The impact of sTfR levels on functional capacity and quality of life (QoL) in non-anemic heart failure (HF) patients with otherwise normal systemic iron status has not been evaluated. We conducted an observational, prospective, cohort study of 1236 patients with chronic HF. We selected patients with normal hemoglobin levels and normal systemic iron status. Tissue iron deficiency (ID) was defined as levels of sTfR > 75th percentile (1.63 mg per L). The primary endpoints were the distance walked in the 6 min walking test (6MWT) and the overall summary score (OSS) of the Minnesota Living with Heart Failure Questionnaire (MLHFQ). The final study cohort consisted of 215 patients. Overall QoL was significantly worse (51 ± 27 vs. 39 ± 20, p-value = 0.006, respectively), and the 6 MWT distance was significantly worse in patients with tissue ID when compared to patients without tissue ID (206 ± 179 m vs. 314 ± 155, p-value < 0.0001, respectively). Higher sTfR levels, indicating increased iron demand, were associated with a shorter distance in the 6 MWT (standardized β = -0.249, p < 0.001) and a higher MLHFQ OSS (standardized β = 0.183, p-value = 0.008). In this study, we show that in patients with normal systemic iron parameters, higher levels of sTfR are strongly associated with an impaired submaximal exercise capacity and with worse QoL.

Thirty-minute Ambulatory Blood Pressure and Blood Biochemistry Measurements in Adults With Hypertension Using Herbs: A Cross-sectional Study

Introduction: Introduction: Globally, there is a growing interest of herbs usage among hypertensive patients. The aim of study was to investigate thirty-minute ambulatory blood pressure (ABP), blood biochemistry measurements and associated factors among hypertensive adults using herbs. Methods: This cross-sectional study was performed among hypertensive adults complementing herbs and attending primary care clinics in Kinta Valley, Perak. Data was collected using standard International Complementary and Alternative Medicine Questionnaire (I-CAMQ) and measurements of thirty-minute ABP and blood biochemistry were conducted using ambulatory blood pressure monitor and point of care units respectively. Results: A total of 86 hypertensive adults using 55 herb combinations were recruited. 80.3% commonly used traditional Chinese medicine, ulam and fenugreek for more than one year. The median age of the participants was 63. The participants complementing herbs had means’ for waist-hip ratio and BMI in the high (0.92 ± 0.07) and overweight (27.14 ± 5.63) range respectively. Mean ± SD reading of systolic blood pressure was 138 ± 14.27 mm/Hg and 81.4% had normal hemoglobin levels. The mean ± SD of total cholesterol and low-density lipoprotein were normal; 166.81 ± 39.40 mg/dl and 85.15 ± 34.34 mg/dl with higher triglyceride readings 181.02 ± 61.24 mg/dl. SBP (&gt;140 mm/Hg) and age range 61-70, waist/hip ratio (high risk for CVDs) among females and Malay ethnicity were associated with higher TC (p=0.003), HDL (p=0.006), LDL (p=0.001) and Chol/HDL (p=0.036). Conclusion: Complementing drugs with herbs associated with patients aged above 60, females and the Malay ethnicity. The patients’ attitude of complementing drugs with herbs showed no impact on the measured physiological and biochemical parameters. A randomized controlled trial with a fixed herb regime is warranted.

Associations among Food Systems, Food Environments, Food Choices, Food Security, and Nutrition Transition in Limpopo Province, South Africa: A Cross-Sectional Study.

A cross-sectional study was applied to investigate the influence of food systems and food environments on food choices and nutrition transition of households in Limpopo province, South Africa. A sample of 429 households was systematically selected using a paper selection draw from three districts. This paper determines the association among food systems, food environments, food choices, and nutritional measurements of the respondents. A validated questionnaire was used. Most of the respondents responsible for food procurement were females (80.4%). There was a significant association (p < 0.001) between proximity to food stores and dietary diversity of the households. Staple foods such as bread, maize, rice, samp, and mealie rice were available in almost all surveyed households (95.6%). More than half of the households (59.8%) had home gardens in their yards. Almost half of the households (48.4%) had a low Dietary Diversity Score. The study further revealed that 46.0% of households were food secure. Over a third (36.2%) of the respondents were obese, and 32.5% were diabetic. The mean total blood cholesterol was 3.69 ± 0.74 mmol/L. A high percentage of both females (89.6%) and males (91.5%) had normal hemoglobin levels. Almost half of the respondents had normal systolic blood pressure levels (45.6%), and nearly a quarter had high diastolic levels (21.4%). The 25 coping strategies were applied during food shortage periods. Even though the food environments provided both obesogenic and protective foods, the consumption of unhealthy foods was high.

Diffuse alveolar haemorrhage in children hospitalised in a tertiary‑level hospital: A retrospective descriptive study.

Diffuse alveolar haemorrhage (DAH) is considered a rare condition in children. There is no consensus on the management of DAH syndromes in Africa or other low- and middle-income countries. In this brief report, the clinical characteristics, management and outcomes of children treated for DAH in the Chris Hani Baragwanath Academic Hospital paediatric pulmonology unit in Johannesburg, South Africa are described. Fifteen children were included in this case series, of whom 11 (73.3%) presented with severe microcytic anaemia. Of the 11 children who had bronchoalveolar lavage, 9 (81.8%; 60.0% of the total) had haemosiderin-laden macrophages on microscopy. Only 5 children had a lung biopsy, of whom 3 (60.0%) had capillaritis. All the children were started on oral prednisone at presentation, and 11 (73.3%) received additional complementary treatment. Nine children (60.0%) had normal haemoglobin levels 1 year after initiation of treatment. Our series supports previous reports that DAH is uncommon in children. A large proportion of our patients responded well to treatment despite some resource limitations. The study provides additional data on children presenting with diffuse alveolar haemorrhage in a South African tertiary hospital. There is a need for South African pulmonologists to come together and conduct a national audit of these patients in different hospitals to determine the incidence in our country, as well as to inform a management plan in the presence or absence of specialised tests.

The Effect of Delayed Cord Clamping (DCC) on Haemoglobin Levels and Oxygen Saturation Levels in Newborns

Background: The case of iron deficiency anaemia in infants is a serious health problem because it interferes with mental and cognitive development. DCC prolongs blood flow from the placenta to the baby through the umbilical cord, increases blood volume, and optimizes oxygen transfusion which might prevent anemia and promote effective self-breathing. Objective: To determine the effect of DCC on Haemoglobin Levels and Oxygen Saturation Levels in Newborns. Method: Experimental research with Post-test Only Control Group design. The total Sampling method was used on 30 newborns as the samples, with 15 intervention groups and 15 control groups. Data collection used the Delayed Cord Clamping procedure, observation sheets, Easy Touch GCHb tool, and Baby SpO2. An Independent T-test was used to process the data. Results: Based on the experiment on 30 infants, it found that the average hemoglobin level of new-borns with the Delayed Cord Clamping treatment was 22.07 gr/dL higher than the hemoglobin level of new-borns without the Delayed Cord Clamping treatment of 17.79 gr/dL. In addition, the average oxygen saturation level of newborns with the Delayed Cord Clamping treatment was 87.4% more than that of newborns without the Delayed Cord Clamping treatment of 77.4%. Conclusion: DCC affects Haemoglobin Levels and Oxygen Saturation Levels in Newborns in the Work Area of the Aikmel Regional Health Centre. There is a need to increase information about the benefits of DCC among health workers.

Pengaruh Paritas Dan Hemoglobin Terhadap Kejadian Preeklamsia

Preeclampsia is one of the leading causes of maternal morbidity and mortality in the world. Parity factors and hemoglobin are suspected of increasing the incidence of preeclampsia. This study aims to determine the effect of parity and hemoglobin on the incidence of preeclampsia. This research is an observational analytic study with a prospective design. The population in this study were preeclampsia pregnant women and healthy pregnant women at Aghisna Medika Kroya General Hospital and Cilacap Regional General Hospital in August–November 2021, with the following inclusion criteria: gestational age 20 weeks, single pregnancy, willingness to become research subjects, and having gadgets. Exclusion criteria were pregnant women who had incomplete medical record data. A total of 36 respondents in the case group were taken by total sampling technique, and 36 respondents in the control group were taken by purposive random sampling technique with a ratio of 1:1. Statistical test using Chi-Square The results showed that 63.89% (23 people) in the case group and 58.33% (21 people) in the control group were multiparas (p = 0.326 0.05), while 69.45% (25 people) in the case group and 58.33% (21) in the control group had normal hemoglobin levels (p = 0.326 0.05). These data show that there is no effect of parity or hemoglobin level on the incidence of preeclampsia.