Normal Activity Levels Research Articles

A random encounter model for wildlife density estimation with vertically oriented camera traps

AbstractThe random encounter model (REM) estimates animal densities from camera‐trap data by correcting capture rates for a set of biological variables of the animals (average group size, speed and activity level) and characteristics of camera sensors. The REM has been widely used for setups in which cameras are mounted on trees or other structures aimed parallel to the ground. Here, we modify the REM formula to accommodate an alternative field of view acquired with vertically oriented camera traps, a type of deployment used to avoid camera theft and damage. We show how the calculations can be adapted to account for a different detection zone with minor modifications. We find that the effective detection area can be close to a rectangle with dimensions influenced by the properties of the Fresnel lens of the camera's motion sensor, the body mass of different species and the height of the camera. The other REM parameters remain the same. We tested the modified REM (vREM) by applying it to wildlife data collected with vertically oriented camera traps in Bardia National Park, Nepal. We further validated that the effective detection area for the camera model used was best approximated as a rectangle shape using maximum likelihood estimation. Density estimates obtained broadly matched independent density estimates for nine species from the previous studies in Bardia with varying body sizes by four orders of magnitude. We conclude that these modifications allow the REM to be effectively used for mammal density estimation for species with a wide range of body sizes, with vertically oriented camera traps.

Покращення рухової активності в учнів 5 класів засобами рухливих ігор

The purpose of the work is to substantiate theoretically and verify experimentally the effectiveness of the method for improving 5th grade students’ motor activity by means of mobile games. Material and methods. The pedagogical experiment was carried out on the basis of the Krolevets Lyceum No. 1 of the Krolevets City Council of the Sumy Region. It enrolled 32 students of 5th grade from the main medical group. They were divided into a control group (CG, n=16, 5-A grade) and an experimental group (EG, n=16, 5-B grade). The term of the pedagogical experiment was September-November, 2023. Pupils of CG and EG studied according to the Model curriculum "Physical culture. 5-6 grades" for institutions of general secondary education. During Physical Education lessons in the CG, the teacher followed the planned tasks and work plan. A developed method of improving motor activity by means of mobile games was implemented in EG. Research methods: theoretical analysis of scientific and methodical literature, pedagogical experiment. The level of motor activity was determined on the basis of a set of indicators: the time of students’ motor activity with a reflection of its content and quality at different moments of the regime, which was determined with the method of individual timing; the amount of motor activity using the pedometry method for quantitative assessment of motor activity; the intensity of motor activity by the pulsometry method (calculation of heart rate in bpm) when various types of muscle activity were performed; methods of mathematical statistics. The results. At the ascertaining stage of the pedagogical experiment, the following indicators of the 5th grade students’ motor activity level were obtained: in CG, 3 students (19%) had a high level, 7 students (44%) had an average level, and 6 students (37%) had a low level. In EG, 3 students (19%) had a high level, 6 students (37%) had an average level, and 7 students (44%) had a low level. It is necessary to note that the indicators of CG and EG were at the same level. At the formative stage of the pedagogical experiment, a method for improving the motor activity of 5th grade students by means of mobile games was developed and implemented. The developed method was implemented into all forms of physical culture and health work in institution of general secondary education. Its content included mobile games directly during Physical Education lessons and during other forms. The developed method was implemented in three directions, in particular with students, teachers and parents. At the control stage of the pedagogical experiment, the following indicators were obtained: in CG, 4 students (25%) had a high level of motor activity, 7 students (44%) had an average level, and 5 students (31%) had a low level. In EG, 6 students (38%) had a high level of motor activity, 7 students (44%) had an average level, 3 students (18%) had a low level. Thus, in CG there is a significant percentage of 5th grade students who have a low level of motor activity, while in EG there are high and average levels of motor activity among 5th grade students. This fact proves the effectiveness of developed method for improving 5th grade students’ motor activity by means of mobile games. Conclusions. The method we had developed for improving 5th grade students’ motor activity by means of mobile games confirmed its effectiveness during the experimental test and can be recommended for use in the practical activities of a Physical Education teacher.

Spinal muscle characteristics during three different types of locomotion activities among college students with idiopathic scoliosis

Background contextPhysical activities such as walking and climbing stairs are pervasive in human daily life. Individuals with scoliosis frequently encounter dysfunction in their muscle recruitment. Multiple studies have corroborated the presence of muscle dysfunction in individuals diagnosed with scoliosis. However, there is currently a noteworthy research gap regarding the exploration of changes in muscle characteristics and disparities from those observed in individuals without scoliosis during everyday activities, specifically stair climbing.PurposeThis study aims to examine the unique patterns of muscle activity during daily life in individuals with scoliosis and distinguish the specific differences between scoliosis patients and the healthy controls. The findings of this study are significantly important for the future accurate assessment of scoliosis and the development of rehabilitation treatment plans.Study designCase–control study.Sample sizeTwenty eight idiopathic scoliosis patients and twenty eight controls.Outcome measuresRoot Mean Square(RMS), Maximum Voluntary Isometric Contraction(MVIC)%, RMS ratio(RMS convex / RMS concave).MethodsThe surface electromyography (sEMG) device used in this study was the Delsys Trigno, with a sampling frequency of 1500 Hz. It recorded the activation level, peak contraction, and average activation level of the erector spinae (at T6, T10, and L3 levels), gluteus maximus, gluteus medius, external oblique, and rectus abdominis muscles during three different types of locomotion for both the 28 individuals with idiopathic scoliosis and the 28 control participants.ResultsThe movement patterns of the idiopathic scoliosis patients significantly differ from those of the normal population during level walking and ascending or descending stairs. In level walking, there is an asymmetry in the activation levels of the T6 and L3 erector spinae muscles, with lower activation on the convex side compared to the concave side. Similarly, during stair ascent, the activation of the T6 and T10 erector spinae muscles is asymmetric, with higher activation on the convex side than the concave side. Moreover, during stair descent, the activation of the T6 erector spinae muscle is asymmetric, with higher activation on the convex side than the concave side.ConclusionsDuring level walking and stair activities, idiopathic scoliosis patients exhibit pronounced abnormal movement patterns that significantly differ from those of the control group. Under different activity conditions such as level walking, ascending and descending stairs, idiopathic scoliosis patients demonstrate abnormal muscle activation in different segments of the spine. It is crucial for clinicians to prioritize the symmetry of muscle activation in the spinal region of idiopathic scoliosis patients and consider incorporating symmetry training for these muscles.

Diagnosis of canine B-cell chronic lymphoid leukemia with a CD21 negative phenotype using the LT21 clone CD21 antibody in flow cytometry: a case report

BackgroundChronic lymphoid leukemia (CLL) is a hematological disorder characterized by the clonal expansion of small mature lymphocytes that accumulate in the blood and bone marrow. CLL can arise from B-, T-, or natural killer cell clones. The cytological evaluation of blood smears is often the simplest and least invasive method for diagnosing lymphoid leukemia. Immunophenotyping is used to further subclassify the type of lymphoid leukemia.Case presentationA 15-year-old, 4.4-kg spayed female Shih Tzu was presented to the veterinary medical teaching hospital of Kangwon National University. Despite having a normal appetite and activity level, cervical and inguinal lymph node enlargement was noted on physical examination. Complete blood count revealed severe leukocytosis, severe lymphocytosis, and monocytosis. Splenomegaly, hepatomegaly, and lymph node enlargement were detected on radiographic and ultrasonographic examination. Immunophenotyping was performed using peripheral blood mononuclear cells (PBMCs). The majority of lymphocytes exhibited the following profiles: CD3−CD79a− (97.5%), CD4−CD8− (98.6%), CD21−CD79a− (98.4%), CD34− (0.1%), CD45+ (99.6%), major histocompatibility complex class II+ (99.5%), and CD14− (0.5%). Based on the immunophenotyping results, possible differentials considered included the following: the majority of lymphocytes may be natural killer (NK) cell clones, plasma cell clones, or show aberrant expression or loss of CD21 marker due to the neoplastic nature of the cells. Further flow cytometry was performed using antibodies against CD3, CD5, CD94, and granzyme B. The combined results indicated that the predominant lymphocyte subset in the PBMCs was CD3−CD5−CD21−CD94−granzyme B−. To confirm monoclonality and exclude the aberrant loss of CD markers, a polymerase chain reaction for antigen receptor rearrangement (PARR) assay was conducted. The PARR assay, using DNA from blood and lymph node samples, showed B-cell monoclonality. Immunocytochemistry using PBMCs showed that the plasma cell marker Multiple Myeloma Oncogene 1 (MUM1) was not expressed. Therefore, the diagnosis was confirmed to be B-cell CLL.ConclusionImmunophenotyping can help subclassify the type of lymphoid leukemia; however, as tumor cells can show aberrant expression or loss of the CD21 marker, combining immunophenotyping with the PARR assay could yield a more accurate diagnosis.

Genetic analysis of antithrombin deficiency among Thai patients with thrombosis

Hereditary antithrombin (AT) deficiency, primarily caused by mutations of SERPINC1 mutations, is a strong risk factor for occurrences and recurrences of venous thrombosis. While AT activity level measurements may be interfered by several factors, genetic analysis is more definitive for diagnosis. This study aims to address the knowledge gap of genetic basis of AT deficiency among Thai patients. Samples were collected from patients with thrombosis and low AT activities. Cases with acquired causes of low AT were excluded. All 7 exons of the SERPINC1 gene were PCR amplified and subjected to Sanger sequencing. The study included 15 patients and 6 controls with normal AT activity levels. The results revealed the presence of 6 benign single nucleotide polymorphisms (SNPs) located in intron 1, 2, exon 5 and intron 5. Two of these SNPs in intron 2 were first described here. Notably, a novel SNP in exon 3, SERPINC1 c.570 C>G (p.Y190X), was discovered. This is likely pathogenic because the premature stop codon led to a non-functional protein. The results suggest that pathogenic SERPINC1 variants detectable by DNA sequencing are uncommon among Thai patients with low AT activity levels underscoring the role of genetic analysis for definitive diagnosis. Further studies involving larger numbers of patients are required.

Tritium content in water bodies in regions of peaceful nuclear explosions

Sites of peaceful nuclear explosions pose a potential radiation hazard to the territories of the Russian Federation, primarily due to the possible release of radioactivity from the explosion cavity into aquifers and onto the earth's surface. Therefore, it is essential to conduct regular monitoring of anthropogenic radionuclides in drinking water sources in settlements located near the sites of peaceful nuclear explosions. Tritium serves as an indicator of the potential release of other anthropogenic radionuclides. Monitoring its levels in water bodies in regions where peaceful nuclear explosions were perfomed, and comparing this data with that from Roshydromet across the Russian Federation, allows for an assessment of the reliability of the engineering barriers between the central explosion zone and the environment with respect to preventing radionuclide migration into aquifers. One method for evaluating the reliability of these barriers is the assessment of tritium specific activity in drinking water sources. This article presents results of the study involving 220 water samples collected from drinking water sources (wells, boreholes, springs, central water supply systems) and surface waters within 167 settlements across 17 subjects of the Russian Federation, where 50 peaceful nuclear explosions were conducted between 1965 and 1988. The samples were collected between May and September 2024 in the settlements within a 30 km radius of a peaceful nuclear explosion site. Measurements of tritium specific activity were performed using the Quantulus 1220-003 alpha-beta spectrometric radiometer. The research revealed that the specific activity of tritium in underground water sources is significantly lower (Student's test p<0,05) than in surface waters. The average specific activity levels of tritium in boreholes, rivers, and lakes were 3.0, 3.45, and 4.31 Bq/kg, respectively. The specific activity of tritium in drinking water sources within the regions of peaceful nuclear explosions was found to be at the background levels recorded by Roshydromet, ranging from 1.1 to 5 Bq/kg.

“Buy him some Tesla stocks for his baptism”: Gender differences among young savers

This paper investigates gender roles in children’s savings, specifically defined as differences pertaining to age, capital invested, financial activity and portfolio composition, using a sample of 58,000 children. We observe gender differences between young female and male account holders. The average age and activity level of boys are significantly higher whereas girls hold more capital in their accounts. We note that activity interacts with both gender, age and capital, and is decisive in explaining financial behaviour, especially that of boys. We conclude that girls have a lower share of saving in direct-owned stock already before the age of one and among teenagers, particularly ages 15–17 years. We discuss our findings applying structuration theory, differentiating between implicit and explicit parental impact prevailing among adolescents, and the definite caring regarding younger children. For policymakers and managers, awareness that gender differences regarding financial behaviour prevail is an important insight.

Dynamic changes of media prefrontal cortex astrocytic activity in response to negative stimuli in male mice

Astrocytes play significant roles in regulating the central stress response. Chronic stress impairs the structure and function of astrocytes in many brain regions such as media prefrontal cortex (mPFC) in multiple neuropsychiatric conditions, but the astrocytic dynamics on the timescale of behavior remains unclear. Here, we recorded mPFC astrocytic activity in freely behaving mice and found that astrocytes are activated immediately by different aversive stimuli. Astrocyte specific GCaMP6s calcium indicator were virally expressed in mPFC astrocytes and fiber photometry experiments revealed that astrocytes are activated by tail-restraint (TRT), foot shock (FS), open arm exploration, stressor of height, predator odor and social defeat (SD) stress. ΔF/F analyses demonstrated that an unpredictable stimulus such as elevated platform stress (EPS) at the initial encounter induced the most intense and rapid changes in astrocytic calcium activity, while a predictable 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) stimulus resulted in the weakest response with a longer peak latency. In TRT, FS or SD test, a somatic stimulus led to higher average calcium activity level and faster average peak latency in repeated trails. Similar to TMT stimulus, astrocytic calcium activity in elevated plus maze (EPM) test exhibited a smaller average change in amplitude and the longest peak latency during open arm exploration. Moreover, astrocytic calcium activity exhibited different changes across behavioral states in SD tests. Our findings show that mPFC astrocytes exhibit distinct patterns of calcium activity in response to various negative stimuli, indicating that the dynamic activity of astrocytes may reflect the stress-related behavioral state under different stimulus conditions.

Measurement of radioactivity and hazard index of Gonadal dose in selected Cement samples in Iraq.

Given the importance of cement as a basic material in construction, this study was undertaken to evaluate the level of radioactivity in a selected group of cement samples most used in construction to determine whether they are safe for human health. In this investigative study, nine samples of cement, both domestic and imported, that are often used in construction projects in Iraq were gathered. A NaI (Tl) gamma-ray spectrometer (3"x3") was used to measure the radioactivity in the samples. The average specific activity levels in the tested cement samples were 11.373±0.522, 5.795 ± 0.230, and 179.123±2.207 Bq/Kg, respectively. Also calculated was the average of the radium, which was equivalent to 33.449±1.022 Bq/kg. As for the risk indicators, the internal risk coefficient was 0.121±0.004 and external risk coefficient was 0.090 ±0.002. While studying the radiation doses, the values of effective annual internal dose was 0.080 mSv/y, external dose rates were 0.020 mSv/y, absorbed dose ratio was 16.321±0.476 nGy/h, and gamma index was 0.253±0.007. In the end, and depending on what was studied from various variables, with an average of 115.59 Sv/y, the annual gonadal equivalent dose risk (AGED) was calculated. The world average values were used to compare all the results. Finally, it was discovered that the radiation parameter levels of none of the samples had a detrimental effect on human health.

Immune status of students with different levels of physical activity

The nature of changes in the immune system during physical work is a complex process involving many different mechanisms. Research in this direction is an urgent problem. The purpose of the research was to study the indicators of cellular and humoral immunity in students with different levels of physical activity. A total of 77 male students were examined, consisting of 3 groups: 1) with a low level of physical activity (n = 32) – students who were not involved in sports activities on a regular basis; 2) students with an average level of physical activity (n = 22) – beginner sambo wrestlers without sports categories; and 3) students with a high level of physical activity (n = 23) – highly qualified sambo wrestlers – first-class athletes, candidates for masters and masters of sports. In students of all groups, the quantitative content of various phenotypes of lymphocytes in the blood was studied by flow cytometry; serum immunoglobulin levels by laser nephelometry; phagocytic parameters by traditional methods; and oxygen-dependent metabolism of neutrophils by chemiluminescence. In students with a high level of physical activity, the content of T and B lymphocytes in the blood was significantly increased compared to similar indicators of the group with a low level of physical activity and the group of students who did not participate in sports. The concentration of class G immunoglobulin in the blood serum of students with a high level of physical activity significantly exceeded the corresponding values in students with an average level and students not engaged in sports. The highest concentration of class M immunoglobulin was observed in students with high levels of physical activity. Phagocytic activity and phagocytic count in individuals with high levels of physical activity and neutrophils were significantly higher than those of students with medium and low levels of physical activity. The rates of spontaneous and induced chemiluminescence in the groups with high and medium levels of physical activity were significantly higher than in students with low levels. The studies carried out indicate the positive effect of regular training physical activity on the factors of humoral and cellular links of immunity in students in the conditions of the educational environment of a higher educational institution.

Metabolic rate does not scale with body size or activity in some tick species.

Respiration in ticks is highly efficient and exceptionally low. Ticks can survive years between bloodmeals by having low activity and respiration to conserve energetic resources. Our objective was to compare metabolic (VCO2) and activity rates across 6 tick species. We predicted that VCO2 would be different among species and scale linearly with activity and body mass. Activity and CO2 production were measured for 32h in 6 tick species: Dermacentor andersoni, D. variabilis, Haemaphysalis longicornis, Rhipicephalus appendiculatus, R. microplus, and R. sanguineus. Individual ticks were measured for 30min three times to ensure breathing occurred. Absolute and mass-specific VCO2, total activity, body mass, and ventilation patterns were compared among species. As expected, ticks did not always breathe during the 30-minute measurements, especially R. sanguineus. Ventilation patterns differed among species with R. microplus having primarily cyclic patterns and R. appendiculatus having discontinuous gas exchange. VCO2 did not scale with body mass in most species. Haemaphysalis longicornis and R. sanguineus had the lowest VCO2; however, H. longicornis was the second most active species. Life history, including questing behavior and range expansion, could be contributing to differences between species. For instance, H. longicornis had exceptionally low metabolic rates despite above average activity levels, suggesting an energetic advantage which may underlie recently documented range expansions in North America. Our results demonstrate how ticks utilize energetic resources to maximize longevity. Future research describing questing behavior and distribution modeling may help explain differences in metabolic rates and activity and impacts on life history traits.

Monitoring the heart rate variability of servicewomen of the Armed Forces of Ukraine during the legal regime of martial law

The article features the results of the analysis of heart rate variability of 30 female military personnel (n=30). The purpose of this study was to assess the state of regulatory mechanisms of the autonomic nervous system. The analysis of heart rate variability indicators reflects the general level of autonomic regulation, which is important for assessing the physical and psychological state of military personnel. The RRNN parameter had a median of 814.5 ms, which corresponds to the norm for healthy individuals and indicates a normal level of cardiac activity of females being under the research. The SDNN indicator, which characterizes the total effect of autonomic regulation of blood circulation, was 37.4 ms on the median, which also corresponds to the norm and indicates an adequate level of adaptation capabilities of the body. However, RMSSD was at the median below normal, indicating reduced recovery and high levels of stress among female military personnel. pNN50, which reflects the proportion of consecutive RR intervals differing by more than 50 ms, was also below normal, further confirming reduced parasympathetic activity. The LF index was 301.0 ms² on the median of female military personnel, which is at the lower limit of the norm. The result we obtained may indicate a reduced sympathetic influence or a general depletion of adaptation reserves. The VLF indicator, which characterizes neurohumoral regulation, was also below the norm, which indicates a possible depletion of the body's adaptive reserves. Such studies make it possible to detect signs of fatigue or insufficient recovery in time and take the necessary measures to optimize the training process and the performance of official duties. Our research confirms that heart rate variability is an important indicator of the body's adaptive capabilities, especially in the conditions of martial law, where stress and physical exertion are constant factors of influence.

Phytochemical Study of Ethanol Extract of Gnaphalium uliginosum L. and Evaluation of Its Antimicrobial Activity.

This study evaluates the antibacterial and antifungal effects of ethanol extracts from Gnaphalium uliginosum L. derived from freshly harvested plant biomass, including stems, leaves, flowers, and roots. The extract was analyzed using gas chromatography-mass spectrometry (GC-MS) to determine its antimicrobial activity against phytopathogenic bacteria and fungi. Two methods were used in the experiments: agar well diffusion and double serial dilution. Extraction was carried out using the maceration method with different temperature regimes (25 °C, 45 °C, and 75 °C) and the ultrasonic method at various powers (63-352 W) for different durations (5 and 10 min). It was found that the 70% ethanol extract obtained through the ultrasonic experiment at 189 W power for 10 min and at 252 W power for 5 min had the highest antimicrobial activity compared to the maceration method. The most sensitive components of the extracts were the Gram-positive phytopathogenic bacteria Clavibacter michiganensis and the Gram-negative phytopathogenic bacteria Erwinia carotovora spp., with MIC values of 156 μg/mL. Among the fungi, the most sensitive were Rhizoctonia solani and Alternaria solani (MIC values in the range of 78-156 µg/mL). The evaluation of the antimicrobial activity of extracts using the diffusion method established the presence of a growth suppression zone in the case of C. michiganensis (15-17 mm for flowers, leaves, and total biomass), which corresponds to the average level of antimicrobial activity. These findings suggest that G. uliginosum has potential as a source of biologically active compounds for agricultural use, particularly for developing novel biopesticides.

Expanding Beyond Genetic Subtypes in B-Cell Acute Lymphoblastic Leukemia: A Pathway-Based Stratification of Patients for Precision Oncology.

Precision oncology promises individually tailored drugs and clinical care for patients with cancer: That is, "the right drug, for the right patient, at the right dose, and at the right time." Although stratification of the risk for treatment resistance and toxicity is key to precision oncology, there are multiple ways in which such stratification can be achieved, for example, genetic, functional pathway based, among others. Moving toward precision oncology is sorely needed in the case of acute lymphoblastic leukemia (ALL) wherein adult patients display survival rates ranging from 30% to 70%. The present study reports on the pathway activity signature of adult B-ALL, with an eye to precision oncology. Transcriptome profiles from three different expression datasets, comprising 346 patients who were adolescents or adults with B-ALL, were harnessed to determine the activity of signaling pathways commonly disrupted in B-ALL. Pathway activity analyses revealed that Ph-like ALL closely resembles Ph-positive ALL. Although this was the case at the average pathway activity level, the pathway activity patterns in B-ALL differ from genetic subtypes. Importantly, clustering analysis revealed that five distinct clusters exist in B-ALL patients based on pathway activity, with each cluster displaying a unique pattern of pathway activation. Identifying pathway-based subtypes thus appears to be crucial, considering the inherent heterogeneity among patients with the same genetic subtype. In conclusion, a pathway-based stratification of the B-ALL could potentially allow for simultaneously targeting highly active pathways within each ALL subtype, and thus might open up new avenues of innovation for personalized/precision medicine in this cancer that continues to have poor prognosis in adult patients compared with the children.

Physical health of high school students with different levels of motor activity

The physical health of children and adolescents is an indicator of the sanitary and hygienic well-being of an educational establishments, reflects the efficiency of the physical education system at schools and the level of physical activity of schoolchildren. An analysis of physical health indicators (height, body weight, hemodynamic and physiometric indicators) in 252 tenth graders was carried out. It was noted that the majority of adolescents (70–82 %) had functional indicators within the age-sex norm; normal physical development was determined in 60 % of schoolchildren. The results of physical fitness tests showed that the «60 m run» was performed at the level of the gold GTO sign, with an unsatisfactory result of the «flexion and extension of the arms in a lying position» test in girls and low results of the «bend forward from a standing position» test in boys. Statistically significant differences were established in the results of pedometer testing among adolescents of health groups I and II (group 1) and schoolchildren with chronic diseases of health groups III and IV (group 2). The physical activity of adolescents in group 1 was 1817 steps higher on weekdays (p=0.000) and on weekends compared to peers in group 2. According to the survey and pedometer data, every third student (34.6 %) was characterized by a low level of physical activity, an average level was found in 49.5 % of tenth graders, and a high level in 15.9 % of schoolchildren. Thus, the average level of physical activity in most adolescents was at the level of 8–9 thousand steps per day and was characterized by low involvement in sports sections, which requires a system of measures to increase the motivation of children and adolescents to engage in physical education.

Quality of life and activities of daily living one year after Coronary Artery Bypass Graft (CABG) surgery: a cross-sectional study

BackgroundDaily activities have been recommended to minimize the long-term complications of coronary artery bypass as one of the strategies to return to the normal activity level, the effectiveness of which needs further investigation. This study aims to determine the quality of life and activities of daily living one year after CABG.MethodsThis cross-sectional study was performed on 206 patients who had undergone CABG for more than one year in 2018 in the north of Iran. The research instrument was a questionnaire including five sections, Data were analyzed using descriptive statistics and Chi2, Mann–Whitney U, Kruskal–Wallis tests, and a Logistic regression model.ResultThe mean score of quality of life was 31.7 ± 2.04 of 12 to 48 possible scores. About Activities of Daily Living results showed 99.5% and 84.7% of the samples needed help with many of these activities respectively. The mean score of quality of life was significantly different based on sex (p < 0.018) and instrumental activity of daily living (p < 0.0001). A logistic regression model was used to determine the factors related to quality of life. The final model showed cross-clamp duration (OR = 0.33,p = 0.014), length of stay(LOS)in the intensive care unit(OR = 0.42,p = 0.05), and instrumental activities of daily living (OR = 0.08,p = 0.001) predicted patients' quality of life one year after coronary artery bypass grafting.ConclusionAlthough more than half of the samples had a good average quality of life score, due to the lack of definitive treatment for coronary artery disease, it is suggested to consider predictive variables to help plan to improve the quality of life of these patients.

Retransmission performance in a stochastic geometric cellular network model

Suppose sender–receiver transmission links in a downlink network at a given data rate are subject to fading, path loss, and inter-cell interference, and that transmissions either pass, suffer loss, or incur retransmission delay. We introduce a method to obtain the average activity level of the system required for handling the buffered work and from this derive the resulting coverage probability and key performance measures. The technique involves a family of stationary buffer distributions which is used to solve iteratively a nonlinear balance equation for the unknown busy-link probability and then identify throughput, loss probability, and delay. The results allow for a straightforward numerical investigation of performance indicators, are in special cases explicit and may be easily used to study the trade-off between reliability, latency, and data rate.

A 10-week play-based after-school program to improve coordinative abilities and physical fitness capabilities among adolescents: a randomized trial

The average levels of physical activity in children are below the ideal, which may influence children's health and motor competence levels. Therefore, this study aimed to assess the impact of a 10-week play-based after-school program on 50 twelve-year-old students’ anthropometric characteristics (body height and body weight), coordinative abilities (flamingo balance test and T-test agility), and physical fitness (sit and reach, 20-m sprint test, SLJ, CMJ, and handgrip). After baseline assessments, the students were randomly divided into two groups: one participating in a play-based after-school program (experimental group) and the other attending regular PE classes (control group). No differences were noted between the sexes. Analysis revealed baseline differences between groups in body weight, agility T-test, and right-handgrip, with no significant sex differences. Following the intervention, the experimental group demonstrated improvements in the 20-m sprint test (F(1,46) = 11.03, p < 0.01), flamingo balance test (F(1,46) = 9.16, p = 0.004), SLJ (F(1,46) = 5.30, p = 0.03), agility T-test (F(1,46) = 28.30, p < 0.01), and right-handgrip (F(1,46) = 6.59, p < 0.01). In summary, the results suggested that a 10-week play-based after-school program enhances coordinative abilities and physical fitness in 12-year-old children. This underscores the potential advantages of integrating play-based physical activities into schools to promote holistic health and fitness in children.

SIR+ models: accounting for interaction-dependent disease susceptibility in the planning of public health interventions

Avoiding physical contact is regarded as one of the safest and most advisable strategies to follow to reduce pathogen spread. The flip side of this approach is that a lack of social interactions may negatively affect other dimensions of health, like induction of immunosuppressive anxiety and depression or preventing interactions of importance with a diversity of microbes, which may be necessary to train our immune system or to maintain its normal levels of activity. These may in turn negatively affect a population’s susceptibility to infection and the incidence of severe disease. We suggest that future pandemic modelling may benefit from relying on ‘SIR+ models’: epidemiological models extended to account for the benefits of social interactions that affect immune resilience. We develop an SIR+ model and discuss which specific interventions may be more effective in balancing the trade-off between minimizing pathogen spread and maximizing other interaction-dependent health benefits. Our SIR+ model reflects the idea that health is not just the mere absence of disease, but rather a state of physical, mental and social well-being that can also be dependent on the same social connections that allow pathogen spread, and the modelling of public health interventions for future pandemics should account for this multidimensionality.

Analysis of natural occurring radionuclide activity concentration of fish in west coast waters of Sabah, Malaysia

Abstract Fish is an important source of protein in human diets, but concerns arise due to natural radionuclide contamination in food and water sources. The study aimed to assess the concentration radionuclides activities (232Th, 238U, and 40K) in three commercial fish species from west coast waters of Sabah, Malaysia. Additionally, the annual effective dose and cancer risk for adults consuming these fish were evaluated. The concentration analysis was conducted using the inductively coupled plasma-mass spectrometer (ICP-MS) technique. The average concentration levels of radionuclide activity detected, and the annual effective dose was estimated to be much lower than UNSCEAR recommendations. The collective effective dose was estimated at 1.88 μSv y−1 for 232Th, 1.11 μSv y−1 for 238U, and 15.12 μSv y−1 for 40K. The cancer risk for adults from the annual effective dose was also found to be much lower than UNSCEAR and ICRP recommendations. Based on the study’s findings, consuming fish from west coast waters of Sabah is deemed safe. However, it is recommended to establish a long-term monitoring system for radionuclide bioaccumulation in fish to gather valuable information for assessing the potential health risks associated with radionuclides in Malaysia, particularly in the Sabah.