In the paper, the modulation effect of rotor-stator interaction subjected to fluctuating rotation speed is investigated numerically. A quasi-bivariate variable mode decomposition method for analyzing non-stationary flow fields is proposed for the first time. Different from the previous studies, this paper emphasizes the local features of the transient flow field at fluctuating rotation speed. The results show that the impact of fluctuating rotation speed on the impeller force is limited, but it significantly impacts the pressure pulsation at fluctuating frequency. The correlation between amplitude and fluctuation ratio is positive. Meanwhile, the fluctuating rotation speed also induces sidebands centered on the blade passing frequency and its harmonics. The periodic changes in rotational speed lead to frequency and amplitude modulation of pressure pulsations. The magnitude of the instantaneous frequency and amplitude increases as the fluctuation ratio grows. The change in pressure field is well synchronized with the rotational speed, while the change in velocity field lags behind the rotational speed. The variation of pressure field with rotational speed is mainly attributed to two aspects. One is the flow structure at the fluctuating frequency, and the other is the instantaneous component of the flow structure at blade passing frequency.