This paper presents the first method to enable friction in the Third Medium Contact (TMC) method. TMC embeds a solid in a highly compliant medium, which becomes infinitely stiff under ultimate compression, thus allowing forces to be transferred between the solids when the medium between the solids is compressed. This approach is increasingly adopted for integrating internal contact in structural design processes, owing to its continuous, fully implicit characteristics, simplicity, and its stability when applying regularisation to the third medium regions. The lack of friction has previously restricted the use of the TMC method in simulating real-world contact conditions. Here, we address this issue by (1) integrating an anisotropic term into a Neo-Hookean material model to provide shear resistance, and (2) employing a framework inspired by crystal plasticity that includes a yield criterion specifically designed to replicate the effects of Coulomb friction.The effectiveness of the method is demonstrated through two examples: (1) a smooth sliding contact problem and (2) a non-smooth C-shaped structure. Results demonstrate a close agreement with reference solutions obtained by a conventional Lagrange multiplier approach. While the method, for now, requires user-defined slip directions, it represents a significant advancement by enabling the integration of friction into TMC, thereby broadening its applicability to problems involving realistic frictional contact. Future research should focus on restoring the fully implicit nature of TMC in the presence of friction, and on developing automated slip direction definitions to enhance usability and expand the method’s versatility.