Abstract Background During segmentectomy for early-stage non-small cell lung cancer (NSCLC), the recommended distance between the tumour and the intersegmental plane is at least 1 cm and the recommended ratio between tumour and surgical margin (M/T) should be at least 1. Aims The aim of the study is to evaluate the association between surgical margin and the risk of recurrence, as well as overall survival, after pulmonary segmentectomy. Methods Single centre study of consecutive patients undergoing pulmonary segmentectomy for cT1N0M0 NSCLC from January 2017 to December 2022. Results In total, 291 patients (median age: 69 years) underwent segmentectomy for cT1a (n=65), cT1b (n=152) and cT1c (n=74) cN0 NSCLC. Surgical approach was performed by video-assisted thoracic surgery in 99% and conversion thoracotomy was necessary in 2.4%. Single segmentectomy was performed in 183 patients (63%). The median number of dissected lymph nodes was 7 (IQR 4-12). The median size of tumour was 15 mm (IQR 11-20). The median surgical margin was 13mm (IQR 7-22) with 32% of patients had surgical margin of less than 10mm with only one patient with R1 resection. M/T ratio >1 was achieved in 49%. Nodal upstaging was found in 14 patients (5%). During the follow-up, 63 patients (21%) were lost and removed from analyses. Local recurrence was observed in only 3 patients (1%) and distant in 19 patients (8%). Recurrence free survival was significantly associated with PET FDG uptake > 3 (HR:4.89), pleural invasion (HR: 3.02) and nodal upstaging (HR: 3.79). However, surgical margin <10 mm or ratio < 1 were not correlated with increased recurrence (HR: 0.78; p=0.624) (HR: 0.69; p = 0.404) or poorer survival (HR: 1.14; p=0.806) (HR: 1.73; p= 0.309), respectively. Conclusion Our preliminary data indicates that local recurrence is infrequent after pulmonary segmentectomy for cT1N0 NSCLC, even with a limited surgical margin.