ABSTRACTIn order to analyze non-stationary signals, like Electroencephalogram (EEG), it is sometimes easier to segment signals into pseudo-stationary segments. In this paper, the cascade of linear predictive coding (LPC) and non-linear Volterra filter is employed for modeling of noise in EEG signal and this methodology is applied to the procedure of change-point detection, for estimating the number of change-points and their exact location which is a powerful way to detect the change-points as precisely as possible. The earlier results are completed by constructing algorithms that use the cascade of LPC and non-linear Volterra filter for modeling the relation between noisy signal and noise in practical situations. In a Bayesian configuration, the posterior distribution of the change-point sequence is constructed and then Markov Chain Monte Carlo procedure is used for sampling this posterior distribution. The simulation results for segmentation of synthetic and real EEG data show that by applying our newly proposed methodology, the specificity and sensitivity of the segmentation are highly improved. In the case of synthetic data, the change-points are estimated completely precise (100% correct) in 70% of times and they are estimated with at least 98% accuracy in other times.