The present investigation addresses the mixed convection two-phase flow of dusty Oldroyd-B fluid towards a vertical stretching surface in the presence of convective boundary condition and nonlinear thermal radiation. The fluid and dust particles motion is coupled only in the course of drag and heat transfer between them. The Stokes linear drag theory is employed to model the drag force. The numerical solutions based on the Runge-Kutta-Fehlberg 45 scheme with shooting method are presented for both fluid and particle phase velocity and temperature fields. Further, numerical results are obtained for skin friction factor and local Nusselt number of prescribed values of pertinent parameters. The results are presented graphically and the physical aspects of the problem are analyzed. The obtained results are validated with existing results and found to be in good agreement. It is found that the mass concentration of the dust particle parameter plays a key role in controlling flow and thermal behaviour of non-Newtonian fluids.