In this work, we reveal possibility using information soliton to resist senescence of certain important bio-excitations (such as Davydov solitons) which play a fundamental role in information processing of life. For this goal, a type of external field interaction with original system is introduced. This field enables the total system to be described by a nonlinear Master equation. Then we found that the nonlinear term in the equation drives the initial excitation to evolve as a kind of information soliton asymptotically. It is this information soliton to resist decaying of the excitations. This provides a constructive way to prolong age of biological excitations by exerting an external field, which forms a basis used in medical devices or treatments.
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