A mathematical analysis for a steady, incompressible, laminar Carreau nanofluid flow over a porous cone and wedge is considered. The novelty of this research work is to scrutinize an exponential space-dependent Cattaneo–Christov heat flux and quadratic Rosseland approximation effects. Two-phase nanofluid model, i.e., Brownian motion, and thermophoretic effects are included. This study also employs non-linear thermal radiation and convective surface boundary conditions to investigate heat transport phenomena. The Carreau nanofluid boundary layer equations are derived using the standard boundary layer approximations. By applying the similarity transformations, the managing set of partial differential equations (PDEs) becomes a system of connected non-linear ordinary differential equations (ODEs). The resultant non-linear ODEs are solved numerically utilizing the numerical method, particularly the bvp4c function in MATLAB. The significances of the fluid motion are visualized by sketching several Carreau nanofluid flow’s relevant parameters using graphic outputs. The effects of a wide range of thermophysical variables on liquid properties including velocity, temperature, concentration, skin-friction, Nusselt number, and Sherwood number are investigated and discussed. This study’s findings are compared to previously announced results within a limited range, where strong validation was seen. The results demonstrate that the opposite mechanism is observed with repercussion of Weissenberg number (We) on velocity profile and concentration, the enhancement of We increases the momentum boundary layer while it reduces the concentration boundary layer. The outcomes could be applied to the cooling of equipment, electronics, and various industrial units.