Nonsyndromic Wilms Tumor Research Articles

Association of nonsyndromic Wilms tumor with premature centromere division

American Journal of Medical Genetics Part AVolume 124A, Issue 3 p. 332-332 Correspondence Association of nonsyndromic Wilms tumor with premature centromere division Károly Méhes, Corresponding Author Károly Méhes karoly.mehes@aok.pte.hu MTA-PTE Research Group of Clinical Genetics, University of Pécs, Pécs, HungaryJózsef Attila u. 7, H-7623 Pécs, Hungary.Search for more papers by this authorP. Kajtár, P. Kajtár Department of Pediatrics, University of Pécs, Pécs, HungarySearch for more papers by this authorG. Kosztolányi, G. Kosztolányi Department of Medical Genetics and Child Development, University of Pécs, Pécs, HungarySearch for more papers by this author Károly Méhes, Corresponding Author Károly Méhes karoly.mehes@aok.pte.hu MTA-PTE Research Group of Clinical Genetics, University of Pécs, Pécs, HungaryJózsef Attila u. 7, H-7623 Pécs, Hungary.Search for more papers by this authorP. Kajtár, P. Kajtár Department of Pediatrics, University of Pécs, Pécs, HungarySearch for more papers by this authorG. Kosztolányi, G. Kosztolányi Department of Medical Genetics and Child Development, University of Pécs, Pécs, HungarySearch for more papers by this author First published: 09 June 2003 https://doi.org/10.1002/ajmg.a.20311Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume124A, Issue330 January 2004Pages 332-332 RelatedInformation

Association of nonsyndromic Wilms tumor with premature centromere division (PCD).

Wilms tumor was discovered in a 22-month-old otherwise healthy girl. Her pretreatment karyotype proved to be normal 46,XX with total premature division (PCD) in 21% of her lymphocyte mitoses. This phenomenon was not seen in the parents. PCD was found in less than 4% of lymphocyte mitoses of five other children with Wilms tumor. The individual finding provides further evidence for a relation of PCD to tumorigenesis; however, elucidation of the question needs further systematic studies.