Health is the most basic human right and one of the most important indicators of sustainable development. Individuals, communities and societies depend on healthy ecosystems support to remain healthy. Well-functioning ecosystems provide goods and services essential for human health. These goods and services include nutrition and food security, clean air and fresh water, medicines, cultural and spiritual values, and contributions to local livelihoods and economic development. They can also help to limit disease and stabilize the climate. However, over the years human activities have been constantly placing pressure on earth’s natural resources to meet the demands of the economies and the needs of a rapidly growing global population, which has resulted in the transformation of basic natural processes such as weather/climate, biogeochemical cycling, and more so the biological diversity in which the evolutionary changes depend. It is projected that less than 25% of Earth’s surface remains free from substantial impacts of human activities and the proportion is set to fall to a mere 10% or less by 2050. Constant human activities are resulting in soil, water and air pollution, increased emissions of greenhouse gases, deforestation and land use change, expanded urban areas, introduction of non-native species, and inadequately planned development of water and land resources to meet food and energy needs. These changes are having both direct and indirect impacts on our climate, ecosystems and biological diversity and human health. Thus, the integrated course of action that involves both individual and the government efforts must be instituted to tackle both human-induced drivers of biodiversity loss, disease emergence and the loss of ecosystem services that support health and general human well-being.