We consider two-body and quasi-two-body decays of the type f_1 rightarrow f_2 B, where f_1 and f_2 are spin-1/2 fermions and B a spin-0 or spin-1 boson. After recalling the non-covariant formalism for decay amplitudes, we derive the expression of the differential decay width and of the polarizations of the final spinning particles, both on- and off-shell. We find an intriguing geometrical interpretation of the results about the polarization. We also illustrate some methods for measuring the polarizations of the resonances and for optimizing data analysis. Then we propose applications to semi-leptonic weak decays, with a major attention to the T-odd component of the polarization; this may help to find, simultaneously, possible time-reversal violations and hints to physics beyond the standard model. We suggest also a CPT test. Last, we discuss some T-odd observables for the production process of f_1 and for the study of the strong final state interactions of non-leptonic decays.