Non-conventional Treatment Research Articles

Case Report: Grade II Hypertension Accompanied by Obesity with Consumption of Propolis Herbs

Hypertension is often said to be a silent killer, because it is a deadly disease without being accompanied by symptoms first as a warning for the victim. Hypertension with the incidence of obesity is still common. The prevalence of hypertension accompanied by obesity also continues to increase. According to some studies, obesity and hypertension have a meaningful relationship. One alternative treatment that can be an option to lower blood pressure is herbal therapy. Herbal medicine is classified as complementary medicine is a phenomenon that appears today among many other non-conventional treatment phenomena, such as treatment with herbs or herbal therapy, acupuncture, and cupping. The use of herbs is one of the alternative treatments chosen by the community other than conventional (medical) treatment.One of the natural products produced is propolis. Propolis is one of the natural products produced by bees and is widely used as a medicine or supplement, anti-inflammatory, disease treatment, accelerating wound healing, and others. The patient in this case is a woman with the age of 50 years. Patients come with complaints of dizziness, headache and low back pain accompanied by a history of hypertension, and obesity. The patient was diagnosed with Grade 2 Hypertension on Treatment, and Obesity was given therapy in the form of Amlodipine 10 mg 1x1, Paracetamol 500 mg 3x1 and Vitamin B Complex 2x1.Hypertension suffered by patients is hypertension obtained due to several predisposing factors in patients, namely diet, obesity, age, and gender.

Assessment of surface and groundwater quality in Tikamgarh city, Madhya Pradesh, India

Surface water and groundwater are primary resources for communities living in arid and semi-arid regions. The expansion of industrial and agricultural practices has raised pressure on natural resources. Water quality assessment provides valuable information about potential of resources for intended uses. The correlation study was carried out on the physicochemical parameters of surface water and groundwater in the Tikamgarh city. The physicochemical parameters, such as pH, total dissolved solids (TDS), total hardness (TH), calcium (Ca2+), magnesium (Mg2+), total alkalinity (TA), sulphate (SO42-), fluoride (F-), iron (Fe), nitrate (NO3-), chloride (Cl-) and turbidity were analysed to determine correlation between parameters. The grab sampling technique was adopted to collect water samples from selected dug wells and reservoirs. The results of physicochemical parameters were fitted in the correlation coefficient equation to predict probable values of different parameters for selected locations. Results of the correlation study showed that calcium and TH are strongly correlated, followed by TH with chloride. However, Ca2+, TH, Cl-, TA, TDS, SO42-, and iron show a high correlation. The findings show that water quality can be managed by controlling TH and TDS concentrations through conventional and non-conventional treatment methods.

Biotechnological Approach to Treat Textile Dyeing Effluents: A Critical Review Analysing the Practical Applications

Although the textile industry is one of the significant contributors to the global economy, approximately 10% of the annual global dye production, amounting to 7 × 106 tonnes and spanning a spectrum of 10,000 different dye variants, is wasted in the dyeing process and subsequently released into the environment. Following the dyeing and processing stages, this waste contributes to environmental pollution, making the textile industry account for 20% of the overall industrial water pollution worldwide. Traditional treatment of effluents is burdensome for the majority of textile units that are micro-scale enterprises. A significant challenge is that there isn't a single, commercially viable way to efficiently treat wastewater from textile industries. Scholars from several disciplines are working together to investigate novel approaches that are assiduously directed at addressing environmental issues by minimising waste, thereby promoting sustainability, circular economy, and industrial symbiosis. This study aims to address the challenges associated with the treatment process of textile dye-related effluents by conducting a comprehensive analysis of recent research on treatment processes and advancements and exploration of biotechnological treatment methods that are focused on achieving the reuse of treated water. The review covers different processes, traditional, current and emerging techniques, and it emphasises their use in practical situations. Also, the efficiency, specificity, and environmental friendliness of different biotechnological approaches are discussed offering a comparison of their benefits and drawbacks. A holistic remediation approach is advocated by harmonizing both conventional and non-conventional treatment methods for a more comprehensive solution.

Ancient medicine for a modern disease: traditional Amazonian medicine to treat substance use disorders

ABSTRACTBackground: There exists an underexploited opportunity to develop innovative therapeutic approaches to SUDs based upon the complementarity between modern and traditional health systems.Objectives: Illustrate the feasibility and potentiality of such an approach through the comprehensive description of Takiwasi Center’s treatment model and program, where health concepts and practices from traditional Amazonian medicine work synergistically with modern psychotherapy and medicine in an intercultural dialog to assist in the rehabilitation of people suffering from SUDs.Methods: The description was built from a review of the literature, institutional data, participatory observation and unstructured interviews with staff, researchers and patients during treatment.Results: Since the foundation of the Takiwasi Center in 1992 in the peruvian Amazon, more than a thousand patients with different socio-cultural, ethnic and religious backgrounds have received residential treatment. We present how traditional Amazonian medicine techniques and health concepts cooperate to complement modern psychology in a therapeutic community setting and propose some hypotheses about the neurobiological, psycho-emotional and spiritual healing mechanisms triggered by the program to help people identify and heal the roots of their substance misuse and addictive behavior. We also summarize quantitative outcomes during treatment showing significant improvements in a wide variety of mental health indicators.Conclusion: Takiwasi Center’s program is an option for people seeking non-conventional treatment who are sensitive to traditional Amazonian medicine practices and ready to explore the roots of their addiction. From this intercultural approach, some lessons could emerge toward a broader understanding of SUDs that may result in better patient care.

Effect of melatonin on sleep quality and EEG features in childhood epilepsy: a possible non-conventional treatment.

Sleep and epilepsy are characterized by a bidirectional relationship. Indeed, epilepsy predisposes to the development of sleep disorders, while sleep deprivation may exacerbate epilepsy. In addition, antiseizure medication can disrupt normal sleep architecture. Therefore, adequate sleep hygiene could lead to improvement in seizure control. The present study aimed to evaluate the effect of melatonin on seizure frequency, EEG tracing, and sleep in children with focal idiopathic epilepsy. This observation study evaluated the effect of 4 mg oral melatonin in ameliorating sleep-wake cycle, seizure frequency, and EEG features in children with focal idiopathic epilepsy of infancy. Twenty children were enrolled from September 2020 to August 2021. The study consisted of serial controls at enrollment (t0), at 3 months (t1), and at 6 months (t2) including neurological examination, questionnaire about sleep disturbances (CSHQ), and EEG. A significant improvement in sleep quality and daytime sleepiness was observed after melatonin supplementation. Furthermore, we observed a noteworthy improvement in EEG tracing at t2 that exhibited a significant correlation with improvements in CSHQ scores. The studies conducted so far to evaluate the effect of melatonin in persons with epilepsy do not lead to definitive conclusions. Despite the small population sample and the study design, we report sleep and EEG improvement after melatonin administration in our cohort. Larger studies are needed to further study the neuroprotective and anticonvulsant properties of melatonin.

Incidental findings on preoperative head and neck MRI for orthognathic surgery in jaw deformity patients

ObjectiveImaging is a critical component of orthognathic treatment. Magnetic resonance imaging (MRI) is a non-invasive method for observing the temporomandibular joint (TMJ). At our institution, MR images of the TMJ are also used when planning treatment for jaw deformities, head and neck screening images are also acquired using a head coil during MR imaging of the TMJ to confirm the presence of incidental findings (IFs) of head and neck lesions. IFs may require additional examination and/or treatment, even if the lesion is asymptomatic. This article presents a review of diseases detected as IFs during MR imaging. Case reports are also presented in which the detection of an IF affected the management of the jaw deformity. MethodsReports of 401 patients with jaw deformities who underwent TMJ MR imaging including head and neck screening before preoperative orthodontic treatment were retrospectively reviewed. ResultsAsymptomatic IFs were detected in 89 patients on screening images performed simultaneously with the TMJ MR imaging. The most common site was the maxillary sinus, and the most common lesions were inflammatory lesions. Although most of the IFs were not clinically significant, 10 required treatment prior to orthognathic treatment or required more detailed examination. ConclusionsAlthough small in number, some of the IFs detected in this study required the use of non-conventional treatment strategies. Our approach of combining TMJ MR imaging with head and neck screening assists not only in evaluating the TMJ but also in detecting lesions that are difficult to detect in radiographic images.

Janus film evaporator with improved light-trapping and gradient interfacial hydrophilicity toward sustainable solar-driven desalination and purification

Solar-driven desalination and purification offers a promising approach to water treatment, while the clean water yields under natural sunlight can be further increased by developing well-designed evaporators. Herein, a TiN/GO//GO Janus film was fabricated to realize the synergetic effect of effective photothermal conversion and water transportation. The top TiN/GO hybrid layer possesses high solar absorption and thermal conversion efficiency, while the bottom GO layer promotes expeditious water transport. Moreover, the film maintains gradient interfacial hydrophilicity due to the reservation of oxygen-functional groups, which facilitate the formation of thin liquid film at water-film interface and increase heat utilization efficiency. Therefore, the Janus film is demonstrated to possess high evaporation rate of 1.70 kg m−2 h−1 for various non-conventional water resources under 1 solar illumination, which is comparable or better than most of the film evaporators. The excellent durability is demonstrated in a wide acid–base range (pH 2–11) and salinity range (0–250‰) over 30 cycles. The outdoor device with Janus film exhibits daily water yield of 7.44 kg m−2, indicating a potential application in efficient solar-driven desalination and non-conventional water treatment.

Untargeted metabolomic analysis to explore the impact of soil amendments in a non-conventional wastewater treatment

As non-conventional wastewater treatment, vegetation filters make the most of the natural attenuation processes that occur in soil to remove contaminants, while providing several environmental benefits. However, this practice may introduce contaminants of emerging concern (CECs) and their transformation products (TPs) into the environment. A potential improvement to the system was tested using column experiments containing soil (S) and soil amended with woodchips (SW) or biochar (SB) irrigated with synthetic wastewater that included 11 selected CECs. This study evaluated: i) known CECs attenuation and ii) unknown metabolites formation. Known CECs attenuation was assessed by total mass balance by considering both water and soil media. An untargeted metabolomic strategy was developed to assess the formation of unknown metabolites and to identify them in water samples. The results indicated that SB enhanced CECs attenuation and led to the formation of fewer metabolites. Sorption and biodegradation processes were favored by the bigger surface area of particles in SB column, especially for compounds with negative charges. Incorporating woodchips into soil shortened retention times in the column, which reduced attenuation phenomena and resulted in the formation of significantly more metabolites. Incomplete biodegradation reactions, fostered by shorter retention times in SW column could mainly explain these results.

AN OVERVIEW OF EPILEPSY DISEASES & PRESENT CONDITION OF EPILEPSY IN BANGLADESH

Even though epilepsy is one of the most prevalent and debilitating neurological disorders, our knowledge of its precise pathogenesis and therapeutic rationale is limited. Sixty-five million individuals throughout the globe are living with epilepsy, which imposes a substantial burden in terms of disability, mortality, comorbidities, stigma, and expenses due to seizures. Significant progress has been made in the last decade toward a better understanding of the pathophysiological underpinnings of the illness and the variables that influence its prognosis. These developments have resulted in updated criteria and terminology for the diagnosis and categorization of epilepsy and new conceptual and operational definitions. However, while there has been a significant rise in antiepileptic medications in the last 20 years, around a third of patients still refuse to respond to conventional therapy and take non-conventional treatment. Furthermore, only a tiny percentage of drug-resistant patients get epilepsy surgery, despite the fact that more than half of those who undergo surgery experience permanent independence from seizures. This article aims to introduce readers to the clinical aspects of epilepsy by covering topics including diagnostic methods, risk factors, and treatment strategies, as well as the current scenario of epilepsy in Bangladesh. KEYWORDS: Epilepsy, Prevalence, Causes, Diagnosis, Management.

Penatalaksanaan Terapi Komplementer dan Alternatif secara Holistik untuk Meningkatkan Pemberdayaan Keluarga pada Penyakit Menahun

According Dinas Kesehatan Kabupaten Banjar data, hypertension and diabetes mellitus are the most common in this area. Hypertension and diabetes mellitus are chronic diseases that most suffer from community members in Kabupaten Banja. In providing nursing care to residents who suffer from chronic diseases, it is necessary to increase nurses' confidence in nursing values ​​which are the guidelines and foundations in providing nursing-care, which must be embedded both in individuals, families and communities. Health not only expected but also to be fit for people that apart from being healthy. The holistic concept is the basis and goal of complementary and alternative medicine for individuals or citizens. Complementary and Alternative Therapy is a non-conventional treatment aimed at improving the degree of public health in dealing with chronic illnesses suffered. Results of short interviews with 10 villagers, there were 8 residents who said they often feel bored in taking medicine because it has been too long, so the family needs to provide support. Based on the data above, the author team seeks to improve the health status of the community and is very important in order to achieve a better standard of living. Strategies to achieve health status. The objective of activity is to implement screening of complementary and alternative therapy management to residents, so that local health workers can follow up the problem that’s happen.

Non-Conventional Induction Heat Treatment: Effect of Design and Electrical Parameters on Apple Juice Safety and Quality

The proposed non-conventional induction heating, which combines an MSCP and VDC structure, was proved to have excellent thermal effect. Different from other electric field sterilization, this electrotechnology operates with no electrodes, and it is a continuous-flow process with short-duration (about 20 s). In current study, the parameters related to temperature rise were investigated, including applied voltage, frequency, the diameter of the secondary coil and heating tube, as well as their length, etc. It was demonstrated that a smaller diameter of the heating tube, parallel connection sample coils, and higher frequency were beneficial for the inactivation of microorganisms. At 500 Hz, the optimal condition is 800 V, d1 = 2 mm, and L1 = 10 cm. Notably, the system could inactivate all microorganisms and maintained the physicochemical properties of apple juice at 40 kHz. It suggests that this structural design has the potential for industrial applications and the proposed induction heating can realize the rapid sterilization of liquid food without applying electrodes.

Role of natural products in alleviation of Huntington's disease: An overview

Huntington's disease (HD) is an autosomal cognitive impairment neurodegenerative disorder that is characterized by behavioral and psychiatric disorders followed by dementia. HD is caused by repeated expansion of cytosine-adenine-guanine trinucleotide within the Huntingtin gene ( Htt ), which encodes for polyglutamine repeat in Huntingtin protein (Htt). Although a number of conventional treatment options such as antipsychotic drugs, antidepressants, mood stabilizing agents, anti-anxiety drugs and omega fatty acids are available for HD but all of them are associated with one or more side effects. Herbal products are an alternative remedies used for treatment of diverse pathological conditions are comparatively safe as compared to synthetic molecules. The present review summarizes various clinical and preclinical studies involving phytoconstituents which have been explored for treatment of huntington disease. Literature search was conducted using various electronic database i.e Scopus, Google, Pubmed, Web of Science. Search was conducted using different keywords such as “huntignton disease”, “herbal products”, “phytoconstituents”, “antihuntignton botanicals”, “herbal products for huntington disease”, “natural products for huntington disease” and “phytomedicine for huntington disease”. Further studies were screening by assessing abstracts and cross references and previously published review and research articles. A number of natural products are reported with antihuntington effects in various clinical and preclinical studies and some of them are also available as herbal formulations. Prominent phytoconstituents present in different plants exhibiting antihuntington effects include asiatic acid, celastrol, sesamol psoralen, isopsoralen, quercetin, madecassic acid, catechin, kaempferol, charantin, 6-shogoal, ellagic acid, celastrine, bacoside A, ginkgolide B, withaferin A, curcumin, scopoletin, caffeine, β-sitosterol, vitexin, rutin, apigenin, luteolin, cannabidiol, tetrahydrocannabinol, and resveratrol. The plant extracts containing these phytoconstituents or their isolated components are reported to exhibit antihuntington effect by targeting various enzymes, modulating inflammatory mediators and/or by improving cognitive impairment. Although, various preclinical studies have shown promising effects of phytochemicals in treatment of Huntington disease, but further investigation is required to prove their efficacy and safety in human beings. • Huntington disease (HD) statics and its etiology. • Conventional and nonconventional treatment approaches for HD and their side effects. • Role of antihuntington botanicals in disease treatment. • Mechanism involved in suppression of huntington disease by herbal products.

Kadın İnfertilitesinde Spesifik Olmayan Medikal Tedavi Yöntemleri

Infertility, which is defined as the inability to conceive despite one year of unprotected sexual intercourse, affects 15% of couples. Any patient with infertility by definition or at high risk of infertility may be offered an infertility evaluation. In women older than 35 years, this waiting period can be limited to 6 months, and then infertility evaluation can be started. In women older than 40 years, more urgent evaluation and initiation of treatment is the most important option. Evaluation of infertility must be done by experienced and trained physicians and necessary treatments must be followed by these physicians. Alternative treatment methods can be used in patients who do not respond after standard evaluation steps and generally accepted treatment options. Various supportive treatments come to the fore here. These options are used both to obtain better quality oocytes before treatment and to ensure that more follicles participate in stimulation. Antioxidants and metformin are the most commonly used agents before treatment in women who are thought to have insulin resistance, especially considering that oocyte mitochondrial DNA damage increases in advanced female age. On the other hand, agents such as growth hormone that should be used in a controlled manner by experienced specialists have been found effective in many publications. In the presented article, non-conventional treatment options for infertility are explained.

Trihalomethane evaluation in chlorinated treated drinking water sources in Saudi Arabia (Aseer region a case study)

This study was conducted to assess trihalomethane levels in Aseer region's main chlorinated treated drinking water sources over four consecutive seasons (Summer, Autumn, Winter, and Spring) and to gain a better understanding of trihalomethane occurrence, amounts, and the factors involved in trihalomethane formation in study area particularly. The study covered thirteen varied drinking water sources including five conventional filtration treatment plants for surface water and two non-conventional treatment plants for groundwater in addition to six desalinated and blended drinking water reservoirs. Results of the study indicated that exceeded the permissible concentration of total trihalomethane at conventional filtration treatment plants of surface water with maximum values ranging from 111.16 ppb to 208.76 ppb with dominant brominated trihalomethane as bromoform (CHBl3) and dibromochloromethane (CHClBr2), especially during the summer season. Results also showed a positive correlation between trihalomethane formation and the level presence of some trihalomethane precursors like organic carbon, turbidity, bromide ion, and free chlorine whereas, a correlation was negative with pH values.

Evaluating the Non-conventional Achalasia Treatment Modalities.

IntroductionAchalasia is a primary esophageal dysmotility disorder. Despite the high volume of studies addressing the conventional treatments for achalasia, few are debated regarding the non-conventional treatments, such as cardiectomy, cardioplasty, endoluminal substances injection (ethanolamine oleate, polidocanol, botulinum toxin), stents, and certain drugs (beta-agonists, anticholinergic, nitrates, calcium channel blockers, and phosphodiesterase inhibitors).MethodsA critical review was performed.ResultsEndoscopic, surgical, and pharmacological treatments were included. A qualitative synthesis was presented.ConclusionNon-conventional therapeutic options for treating achalasia encompass medical, endoscopic, and surgical procedures. Clinicians and patients need to know all the tools for the management of achalasia. However, several currently available studies of non-conventional treatments lack high-quality evidence, and future randomized trials are still needed.

Analytical method to monitor contaminants of emerging concern in water and soil samples from a non-conventional wastewater treatment system

Nonconventional wastewater treatments, such as vegetation filters (VFs), are propitious systems to attenuate contaminants of emerging concern (CECs) in small municipalities. The development of standardised multiresidue and multimatrix methods suitable for measuring a reliable number of CEC in environmental samples is crucial for monitoring infiltrating concentrations and for ensuring these systems’ treatment capacity. The objective of this study is to develop and validate an analytical method for the simultaneous determination of CECs, including transformation products (TPs), with diverse physico-chemical properties, in environmental samples. The optimised method is based on sample clean-up and preconcentration by solid-phase extraction (SPE), followed by liquid chromatography electrospray ionization tandem mass spectrometry (LC-MS/MS). The method is able to detect and quantify 40 target CECs, including pharmaceuticals of different classes (analgesics, antibiotics, antihypertensives, lipid regulators, anticonvulsants, antidepressants, antiarrhythmics, beta-blockers, amongst others), hormones and lifestyle products with good reproducibility (variations below 23%), in different water matrices, and 28 CECs, in soil samples. Acceptable recoveries (65–120%) were obtained for most of the CECs in all the matrices. However in the soil samples, as complexity required a prior extraction treatment, the recovery of some analytes was affected, which reduced the number of target CECs. The achieved methodological quantification limits (0.05–5 ng/L and 0.04–1.1 ng/g levels for the water and the soil matrices, respectively) were reasonably low for most CECs. The proposed method was successfully applied to monitor CECs in a VF. The CECs detected at higher concentrations are some of the world's most widely used products (e.g. acetaminophen or caffeine and its main TP, paraxanthine). The results showed an almost 70% reduction in CEC concentrations during infiltration. The groundwater data indicated that the VF treatment operation did not affect the underlying aquifer (Cmax found in GW <1 µg/L).

N03 Medication adherence in relation to Health-related Quality of Life in patients with Inflammatory Bowel Disease – A cross-sectional study

Abstract Background Inflammatory Bowel Diseases are chronic diseases often with complex treatment. The treatment is lifelong and complex and may include several different pharmaceutical groups and sometimes surgery. Not rarely is treatment resistance developed and the treatment may come with different degrees of side effects. Earlier research has shown insufficient to medication adherence and a lower degree of health-related quality of life in patients with inflammatory bowel disease. The aim is to describe the relationship between medication adherence and health-related quality of life in a Swedish population diagnosed with inflammatory bowel disease. Additional research questions are if any risk factors of low medication adherence can be identified from the collected variables. Methods This cross-sectional study included N=206 patients from three different regions in Sweden. The questionnaires MMAS-8 and Short Health Scale were used combined with a questionnaire regarding patient characteristics. The data and patient characteristics were described and analyzed using descriptive statistics. Ethical approval has been received from the Regional Ethical Review Board, Linköping, Sweden (no.: 2015/369-31). Results The majority of patients had Ulcerative Colitis (62.6%) There were no significant differences between the different groups of Inflammatory Bowel Disease regarding patient characteristics apart from having gone through surgical procedures, which were more common in patients with Crohn’s disease. A small correlation was shown between medication adherence and the health-related quality of life dimension social function (rho = -0.146; p &amp;lt;0.05). Medication adherence showed no significant correlations to the remaining health-related quality of life dimensions: disease related worry, symptom burden and sense of general well-being. Possible risk factors identified for low medication adherence were age between 30 and 50, working at high occupational level, and higher educational level. Conclusion The complexity of measuring medication adherence has been established, making it difficult to make any certain conclusions regarding the hypothesis in this report. This study showed no clear association between medication adherence and health-related quality of life in patients with inflammatory bowel disease. However, it visualized the need of optimizing the instruments used to measure medication adherence in individuals with a non-conventional treatment plan

Integrative Healthcare in India: A Paradigm Shift in Modern Medical Education and Practice of 21st Century

The famous Canadian physician William Osler once said that “the good physician treats the disease; the great physician treats the patient who has the disease.” Integrative health holds the same philosophy by bringing together conventional and complementary approaches in a coordinated care for the whole person (body, mind, spirit) rather than giving a specializing care to a particular organ system. Integrative health can be contrasted with alternative medicine in which a person takes nonconventional treatment instead of conventional medicine. According to the Consortium of Academic Health Centers for Integrative Medicine and Health, integrative medicine is defined as “the practice of medicine that reaffirms the importance of the relationship between practitioner and patient, focuses on the whole person, is supported by evidence, utilized all appropriate therapeutic and lifestyle approaches, healthcare professionals and disciplines to achieve optimal health and healing.

Untargeted Metabolomic Analysis to Explore the Impact of Soil Amendments in a Non-Conventional Wastewater Treatment

Untargeted Metabolomic Analysis to Explore the Impact of Soil Amendments in a Non-Conventional Wastewater Treatment

Analytical Method to Monitor Contaminants of Emerging Concern in Water and Soil Samples from a Non-Conventional Wastewater Treatment System

Analytical Method to Monitor Contaminants of Emerging Concern in Water and Soil Samples from a Non-Conventional Wastewater Treatment System