Research work on the adverse effects of noise on annoyance in adults is well documented in Western Europe, but there is a knowledge gap concerning this type of research in Central and Eastern Europe (CEE), South-East Europe (SEE), and Newly Independent States (NIS). The objective of this review was to present findings and to propose future research directions for the studies on the effects of environmental noise on annoyance in adults conducted in these countries. After systematic search in accessible databases, scientific journals, conference proceedings, international and national reports in English and other languages, the authors identified 29 papers to be included to this review: 24 papers related to annoyance due to road traffic noise and 5 papers related to annoyance from other noise sources. In most of the identified studies, a cross-sectional design prevailed and the evaluations were mainly performed subjectively. The lack of recent annoyance studies related to railway and aircraft traffic noise was identified. Only two studies from NIS countries used noise exposure data for the evaluation of population annoyance according to the European Environmental Noise Directive (END). Capacity building in CEE, SEE, and NIS countries is necessary to acquire the "know-how" on how to implement and use the different scenarios for evaluating population annoyance by environmental noise, depending on the availability and suitability of noise exposure data. Particular attention should be given to the possible use of END noise exposure data, where applicable.