We present precise predictions for four-lepton plus jets production at the LHC obtained within the fully automated Sherpa+OpenLoops framework. Off-shell intermediate vector bosons and related interferences are consistently included using the complex-mass scheme. Four-lepton plus 0- and 1-jet final states are described at NLO accuracy, and the precision of the simulation is further increased by squared quark-loop NNLO contributions in the gg -> 4l, gg -> 4l+g, gq -> 4l+q, and qq -> 4l+g channels. These NLO and NNLO contributions are matched to the Sherpa parton shower, and the 0- and 1-jet final states are consistently merged using the MEPS@NLO technique. Thanks to Sudakov resummation, the parton shower provides improved predictions and uncertainty estimates for exclusive observables. This is important when jet vetoes or jet bins are used to separate four-lepton final states arising from Higgs decays, diboson production, and top-pair production. Detailed predictions are presented for the ATLAS and CMS H->WW analyses at 8 TeV in the 0- and 1-jet bins. Assessing renormalisation-, factorisation- and resummation-scale uncertainties, which reflect also unknown subleading Sudakov logarithms in jet bins, we find that residual perturbative uncertainties are as small as a few percent.