Examination of bioactive mother-liquors from previous large scale experiments on the antimicrobial agents from the Nigerian medicinal plant, Erythrina mildbraedii, led to the isolation and structural characterization of two new pterocarpans, erybraedin D and E. Erybraedin D was initially isolated as its apparently artifactual hemiethyl phthalate ester. Both new pterocarpans possess marginal antimicrobial potency in vitro