In emerging economies, exploiting capability advantage is critical to new ventures¡¯ survival and prosperity. Though extant research has noticed the important role of valuable resources in this process, it largely ignores the utilization of strategic flexibility (via resource flexibility and coordination flexibility) in effectively exploiting capability advantage. Addressing this oversight, we examine different direct effects of resource flexibility and coordination flexibility on exploiting capability advantage for new ventures in China. Additionally, we investigate whether managerial ties (via ties with other firms and ties with the government) play a catalyst or retardant role in this process. Our empirical results suggest that while coordination flexibility has a pure positive effect on exploiting capability advantage, resource flexibility has an inverted U-shaped effect. Further, ties with other firms will advance the positive effect of resource flexibility but impede the exertion of coordination flexibility, while ties with the government can promote the utilization of strategic flexibility on exploiting capability advantage.