Neutral Control Condition Research Articles

The use of ‘artificial saliva’ as a neutral control condition in gustatory research: Artificial saliva is not a neutral gustatory stimulus

Distilled water with NaHCO3 and KCl is a solution often referred to as ‘artificial saliva’ because its chemical composition mimics human saliva. It is often used as a control stimulus in gustatory research, especially in neuroimaging, owing to the claim that it does not produce a response in primary gustatory cortex Yet evidence that human research volunteers perceive this liquid as affectively neutral is lacking. Unpublished data from our lab suggested that this solution might be perceived as aversive. This study set out to systematically test the parameters influencing taste neutrality. We used two different concentrations of distilled water with NaHCO3 and KCl, as well as bottled water as a control stimulus. Healthy adults rated all stimuli on two separate scales to rule out an interpretation based on the specifics of a single scale. Our participants rated artificial saliva as aversive on both scales. The bottled water was rated as neutral in valence on both scales, and as significantly less intense in sensation than both concentrations of the artificial saliva. This is the first study to have directly tested the subjective feelings that accompany the ingestion of these oft-used solutions on a trial-by-trial basis. We found that these stimuli, which were previously assumed to be neutral, may not be perceived as such by research participants. Therefore, future gustatory studies should take care when using this solution as a neutral baseline. It is advised that trial-by-trial ratings are collected. Also, depending on the nature of future studies, bottled water may be considered as a preferable neutral baseline.

Heightened degree connectivity of the striatum in obsessive-compulsive disorder induced by symptom provocation

BackgroundNeurosurgical intervention studies have provided direct evidence that the ventral striatum/nucleus accumbens (NAc) mediates symptoms of obsessive-compulsive disorder (OCD), yet meta-analysis of functional neuroimaging studies using symptom provocation revealed no striatal activation differences, and the existing studies reporting hyperactivity found abnormalities in dorsal but not ventral striatal subdivisions. Resting-state neuroimaging evidence holds that corticostriatal areas are more connected both locally and to distant regions, but the functional inferences to be drawn from these altered network characteristics regarding the present experience of OCD symptoms remain limited. MethodsThe present study tested whether symptom provocation induces abnormally high striatal network connectivity using two independent datasets of unmedicated patients with OCD. One study (14 patients, 14 matched controls) required passive viewing of OC-related, emotionally aversive and neutral pictures, the other (21 patients, 21 controls) involved self-referential evaluation of the same picture types, as well as distraction from these stimuli (engagement in a simple task). ResultsHeightened local connectivity of the dorsal striatum occurred during passive viewing of briefly presented OC-related pictures in patients, however group differences were also observed in a neutral control condition. In contrast, distracted symptom provocation selectively yielded local connectivity differences of the ventral striatum, as heightened NAc connectivity to its immediate neighborhood was exclusively observed when OC-related pictures were accompanied by concurrent task demands. LimitationsSmall samples sizes. ConclusionsIn moderately affected patients with OCD, symptom provocation induces a discrete, condition-specific network abnormality anchored in NAc, the location targeted by deep brain stimulation for refractory patients with OCD.

Morality in advertising: An fMRI study on persuasion in communication.

Advertising slogans serve the function of persuasive communication by presenting catchy phrases. To decide whether a slogan is convincing or not, cognitive reasoning is assumed to be complemented by a more implicit and intuitive route of information processing, presumably similar to evaluating normative judgments in moral statements. We employed functional magnetic resonance imaging (fMRI) while Western male subjects judged advertising slogans and moral statements as another decision task with subjective nature. Compared to a neutral control condition that targeted declarative memory and to an aesthetic-related condition, the evaluation processes in both domains engaged the anterior medial prefrontal cortex (mPFC), which is associated with decision-making incorporating personal value. Conjoint activations were also observed in the left temporoparietal junction (TPJ) when compared to the aesthetics condition. Results are discussed with reference to domain-independence, a suspected difference to aesthetic-like appreciations, and functional organization in the mPFC and the TPJ.

Low subjective socioeconomic status alters taste-based perceptual sensitivity to the energy density of beverages

Lower socioeconomic status (SES) is associated with increased consumption of energy-dense foods and sugar-sweetened beverages. Recent findings suggest that the mere perception of having lower subjective SES (SSES) compared to others was sufficient to elicit heightened preferences and consumption of higher energy foods and meals. This increased drive for energy intake associated with low SSES may be accompanied by heightened perceptual sensitivity to the presence of energy in foods, which may aid discrimination and selection of energy-dense foods. The present study tested this prediction by investigating whether acute experiences of low SSES may produce subsequent shifts in perceptual sensitivity to the energy density of beverages. Participants performed two taste tests on 6 iced tea beverages that varied in energy density prior to (at baseline) and after an experimental SSES manipulation. There were no differences in general frequency of ice tea consumption across the SSES conditions. Results revealed that participants were better at perceiving beverages that were higher in energy to be more energy dense following the low SSES manipulation (compared to baseline evaluations). By contrast, participants in the high SSES and neutral control conditions exhibited no overall consistent change in sensitivity to perceived energy density across the beverages following the manipulation. Additionally, no effects of SSES manipulation were observed for rated palatability of the beverages. These findings demonstrate that subjective experiences of having inadequate socioeconomic resources may produce taste-based perceptual shifts that increase sensitivity to the presence of energy in foods, potentially through heightened attentiveness to or expectations of sensory characteristics that signal energy (i.e., sweetness, texture). Such perceptual shifts may have been adaptive for facilitating the discrimination and selection of energy-dense foods in the face of resource insecurity. Importantly, this study suggests that merely perceiving a socioeconomic disadvantage may enhance identification and consumption of energy-dense foods and beverages, which may represent a psychosocial process that contributes to socioeconomic disparities in consumption of energy dense foods, and may be operational via heightened perceptual sensitivity to sensory cues associated with the presence of energy in the consumed food.

I'll cry instead: Mu suppression responses to tearful facial expressions

Tears are a facial expression of emotion that readily elicit empathic responses from observers. It is currently unknown whether these empathic responses to tears are influenced by specific neural substrates. The EEG mu rhythm is one method of investigating the human mirror neuron system, purported to underlie the sharing of affective states and a facilitator of social cognition. The purpose of this research was to explore the mu response to tearful expressions of emotion. Sixty-eight participants viewed happy and sad faces, both with and without tears, in addition to a neutral control condition. Participants first completed an emotion discrimination task, and then an imitation condition where they were required to mimic the displayed expression. Mu enhancement was found in response to the discrimination task, whilst suppression was demonstrated in response to the imitation condition. Examination of the suppression scores revealed that greater suppression was observed in response to happy-tear and sad tear-free expressions. Planned contrasts exploring suppression to neutral faces revealed no significant differences between emotional and neutral conditions. The mu response to neutral expressions resembled that of the happy-tear and the sad tear-free conditions, lending support to the idea that ambiguous emotional expressions require greater sensorimotor engagement. This study provides preliminary evidence for the role of the mirror neuron system in discerning tearful expressions of emotion in the absence of context.

The spatial orienting of the focus of attention in working memory makes use of inhibition: Evidence by hemispheric asymmetries in posterior alpha oscillations

Retroactive cuing of information after encoding improves working memory performance. However, there is an ongoing debate on the contribution of target enhancement vs. distractor inhibition attentional sub-processes to this behavioral benefit. We investigated the electrophysiological correlates of retroactive attentional orienting by means of oscillatory EEG parameters. In order to disentangle excitatory and inhibitory attentional processes, the to-be-memorized information was presented in a way that posterior hemispheric asymmetries in oscillatory power could be unambiguously linked to lateral target vs. distractor processing. We found an increase of posterior alpha power (8–14 Hz) contralateral to the position of non-cued working memory content and a decrease of alpha power contralateral to cued positions. These effects were insensitive to the number of cued or non-cued items, supporting their relation to the spatial orienting of attention. Importantly, only the alpha power increase contralateral to non-cued positions differed reliably from the asymmetry in a neutral control condition, highlighting the importance of an inhibitory mechanism for the retroactive focusing of attention. Furthermore, the alpha power asymmetries relative to the positions of cued and non-cued items predicted the individual susceptibility to interference by irrelevant information during working memory retrieval. These findings indicate that the retroactive orienting of the focus of attention can bias the mental representations of non-spatial stimulus features stored in working memory and thereby promote a target-oriented retrieval process.

Mind the gap between feeling bad and feeling dead: Stress but not death reminders elicit endocrine responses

Stressors and mortality salience share considerable conceptual overlap. Thus, we examined the impact of a standard mortality salience and a standard stress manipulation on the activation of the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis via endocrine measures of stress; a neutral control condition completed the design. The results revealed that stress elicits increased salivary α-amylase and salivary cortisol reactions; however, no endocrine reactions were found in the mortality salience and the control conditions. To the contrary, we did not find any differences regarding positive and negative affect between any conditions. Implications for social and health psychology are being discussed.

Do All Eagles Fly High? The Generic Overgeneralization Effect: The Impact of Fillers in Truth Value Judgment Tasks

Abstract The generic overgeneralization effect is an attested tendency to accept false universal generalizations such as “all eagles fly” or “all snakes lay eggs” as true. In this paper, we discuss the generic overgeneralization effect demonstrated by Polish adult speakers. We asked 313 native speakers of Polish to evaluate universal quantified generalizations such as “all eagles fly” or “all snakes lay eggs” as true or false. The control group of 107 respondents provided data on the acceptance rates of the corresponding generic generalizations such as “eagles fly” or “snakes lay eggs”. By determining the impact of test fillers on the participants’ acceptance rates, the study aimed to identify the scope of the generic overgeneralization effect. We manipulated four conditions: the universal negative, positive, neutral, and generic control conditions. The results showed significant differences between the first two conditions, but neither the negative nor the positive condition differed from the neutral one. The overall acceptance rates of universal statements were 63% for the negative condition, 49% for the positive condition, 55% for the neutral condition, and 90% for the control group. Overall, the participants accepted universal quantified statements at high rates even when they were prompted to reject them. The results may be interpreted as another piece of evidence in support of the generic overgeneralization effect.

Worry alters speed-accuracy tradeoffs but does not impair sustained attention

Worry has been experimentally linked to a range of cognitive consequences, including impairments in working memory, inhibition, and cognitive control. However, findings are mixed, and the effects of worry on other phenomenologically-relevant constructs, such as sustained attention, have received less attention. Potential confounds such as speed-accuracy tradeoffs have also received little attention, as have psychometric and related design considerations, and potential moderators beyond trait worry. The present study investigated the effects of experimentally-induced worry versus a neutral control condition on speed-accuracy tradeoff-corrected performance on a validated measure of sustained attention (88 participants; within-subjects). Moderation by trait worry and trait mindfulness was probed in confirmatory and exploratory analyses, respectively. Worry led to faster and less accurate responding relative to the neutral comparison condition. There was no main effect of condition or trait worry on sustained attention after accounting for speed-accuracy tradeoffs. In exploratory analyses, higher trait mindfulness was robustly related to better post-worry performance, including after controlling for trait worry, general distress, and post-neutral performance, and correction for multiple comparisons. Follow-up analyses exploring dissociable mindfulness facets found a robust relationship between present-moment attention and post-worry performance. Future research should experimentally manipulate mindfulness facets to probe causality and inform treatment development.

Diehard singles: Bachelorhood as a terror management strategy among avoidant men

AbstractThis research examines the motivational underpinnings of late bachelorhood through the lens of terror management and attachment theory. It was hypothesized that, although close relationships reduce existential concerns for most people, for avoidantly attached singles, thoughts of marriage may increase existential concerns. These hypotheses were tested in two studies among Israeli men. In Study 1, thoughts about getting married increased death thought accessibility (DTA) among avoidant singles compared to thoughts about being alone or a neutral control condition. For nonavoidant singles, thinking about future marriage reduced DTA. In Study 2, mortality salience reduced motivations for being in a relationship among avoidant singles and increased such motivation among those low in avoidant attachment. Results suggest that marriage may cause angst among avoidant single men.

The benefits of expressive writing among newly diagnosed mainland Chinese breast cancer patients.

The study aimed to evaluate the effects of an expressive writing intervention on quality of life (QoL) among mainland Chinese breast cancer patients. A total of 118 Chinese breast cancer patients were randomly assigned to one of four groups: a cancer-facts writing condition (CTL group), an emotional disclosure writing condition (EMO group), a self-regulation writing condition (SR group), or a neutral control condition with no writing tasks (CON group). QoL was assessed by FACT-B at baseline, 3-, and 6-month follow-ups. A repeated measure analysis of variance revealed significant effects of time (F = 13.9, P < 0.001, η2 = 0.20) and the time × group interaction (F = 3.5, P < 0.01, η2 = 0.08) on QoL. Residualized change models showed that the CTL, EMO and SR groups reported higher levels of QoL than the CON group at the 6-month follow-up. The EMO group had a higher level of QoL than the SR group. The CTL group had higher level of physical well-being compared to the SR group. Mainland Chinese breast cancer patients shortly after diagnosis benefit from expressive writing. They benefited more from cancer-facts and emotional disclosure compared to self-regulation. The study indicated that the impact of expressive writing may differ due to stage of cancer survivorship, social, and cultural context.

Between placebo and nocebo: Response to control treatment is mediated by amygdala activity and connectivity.

In experimental placebo and nocebo studies, neutral control treatments are often administered for comparison with active treatments, but are of little interest, as, on average, they result in little change. Yet, when considered at an individual level, they fluctuate between baseline and subsequent measurements and may reveal important information about participants' placebo/nocebo responding tendencies. In a paradigm involving application of creams paired with positive, negative and neutral expectations, some subjects rated identical stimuli in the neutral condition as more painful while others as less painful after treatment with inert cream. We divided subjects into two groups based on the median split in these pre-post responses in the neutral control condition, and investigated (a) fMRI signal differences (post minus pre) between the two groups in neutral condition, and (b) seed-based resting state connectivity of the bilateral amygdala, known to be involved in emotional self-regulation, as well as ambiguous stimulus processing and aversive learning. The results suggested that subjects who rated the same pain stimuli after treatment with explicitly neutral cream as more painful showed stronger fMRI activation of the amygdala during the experiment and had higher connectivity between the left amygdala and the striatum at rest. Neutral pre-post changes predicted behavioural placebo/nocebo response in this and two independent datasets. These findings suggest that measuring pre-post change in the neutral control condition might provide important information about subjects' individual differences in placebo/nocebo response. Pre-post changes in pain ratings in neutral conditions are modulated by amygdala activity and connectivity and can be used to predict placebo/nocebo responses.

Recalled saudade is associated with positive affect, close connectedness, and inspiration

We examined the extent to which recalled saudade is associated with positive and negative affect, loneliness, close and societal connectedness (Study 1), self-esteem (Study 2), and inspiration (Study 3). Participants were either asked to think about a past event that makes them experience saudade or about a neutral event and then to complete a written narrative. Then they responded to sets of items assessing affect, connectedness, loneliness, self-esteem or inspiration. Participants in the recalled saudade condition (either students or adults) scored higher on positive affect, close connectedness and inspiration than participants in the neutral (control) condition. There were, however, no differences between conditions regarding negative affect, loneliness, societal connectedness, and self-esteem. These findings were largely consistent with results from previous studies on the closely related concept of nostalgia.

When does anger boost status?

A substantial literature asserts that anger expressions boost status. Across seven studies (N = 4027), we demonstrate that this assertion is often wrong. Rather than boosting status, many anger expressions predictably diminish status. We find that the intensity of expressed anger profoundly influences social perceptions and status conferral. Compared to mildly or moderately angry individuals, extremely angry people are perceived to be less competent and warm, and are thus accorded less status. We also contrast expressions of anger with expressions of sadness across different levels of intensity. At low levels of intensity anger expressions boost status conferral compared to sadness expressions and a neutral control condition, but at high levels of intensity anger expressions harm status conferral compared to sadness expressions and a neutral control condition. Taken together, our findings reveal that the relationship between expressed emotion and status is far more nuanced than prior work has assumed, and that the magnitude of an emotion can substantively moderate its effects.

LikeWant: A new methodology to measure implicit wanting for flavors and fragrances

According to the incentive salience hypothesis framework (Berridge, 2007, 2012; Berridge & Robinson, 1998, 2003; Berridge, Robinson, & Aldridge, 2009), wanting and liking can be dissociated, suggesting that two products having similar liking levels could trigger different wanting behaviors in consumers. Defined as a motivational state that promotes approach toward and consumption of rewarding stimuli, wanting can be measured through the Pavlovian instrumental transfer (PIT) procedure. Having emerged from animal models, the PIT procedure aims to measure the effort exerted by an organism (consumer) to obtain a particular reward (product). By adapting and optimizing existing human PIT procedures, we developed LikeWant, an innovative behavioral method that measures consumers’ motivation to pursue flavors and fragrances as rewards. Two studies were conducted to test the sensitivity of the LikeWant procedure. In the first experiment, we investigated the sensitivity of the LikeWant procedure to measure wanting for a pleasant odor with odorless air as a neutral control. In the second experiment, we assessed the ability of the LikeWant procedure to simultaneously measure wanting for two competing fine fragrances. The results showed that the LikeWant procedure is able to (1) measure wanting for a pleasant odor with odorless air as a neutral control condition and (2) discriminate between two fine fragrances on the basis of their rewarding properties, potentially enabling the use of the procedure in consumer studies.

Comment: Mapping Neutrality Within the Affective Landscape: A Response to Yih, Uusberg, Qian, and Gross

Yih, Uusberg, Qian, and Gross (2019) proposed an appraisal approach to help conceptualize five different states that researchers have used as neutral control conditions. This approach has the potential to enrich our understanding of these states and how they function. Here, we discuss four points to keep in mind while implementing this approach with the hope that these ideas will further assist researchers in understanding how neutrality might fit within the affective landscape.

토크 변동조건에서의 유성기어세트 동적 거동 해석 모델링에 대한 연구

In this paper, to reduce planetary gear noise under the neutral control condition, a dynamic analysis model for multi-stage planetary gear trains of the HMC 6th speed automatic transmissions under a torque fluctuations condition is proposed. The natural frequencies of its system are computed by solving the corresponding eigenvalue problem. Moreover, some forced torque fluctuation response to the planetary gear system is applied to check its influence during neutral control. By undertaking some parameter studies for analysis modeling, an underdrive brake torque fluctuation and underdrive hub inertia are observed to be the most effective factors of the HMC 6th speed automatic transmission’s planetary gear noise under the neutral control condition. To reduce neutral control planetary gear noise, the underdrive torque fluctuation should be reduced whereas underdrive hub inertia should be increased. However, every transmission has some torque fluctuations caused by the valve body control response and friction component characteristic and those also have some manufacturing quality distributions. Therefore, control component inertia is an important item in the neutral control condition. To adapt the neutral control to a next-generation transmission, its control component inertia should be above a certain value.

Awe-full uncertainty: Easing discomfort during waiting periods

ABSTRACTWaiting for uncertain news is a common and stressful experience. We examined whether experiencing awe can promote well-being during uncomfortable periods of uncertainty. Across two studies (total N = 729), we examined the relationship between trait awe and well-being as participants awaited feedback on a novel intelligence test or ratings from peers following a group interaction. These studies further examined the effect of an awe induction, compared to positive and neutral control conditions, on well-being. We found partial support for a relationship between trait awe and well-being during waiting periods, particularly with positive emotion. We also found partial support for the benefits of an awe induction: People consistently experienced greater positive emotion and less anxiety in the awe condition compared to a neutral control condition, although these benefits did not always improve upon the positive control experience. Importantly, these benefits emerged regardless of one’s predisposition to experience awe.

The Role of Attitude Strength in Behavioral Spillover: Attitude Matters-But Not Necessarily as a Moderator.

Studies on how one behavior affects subsequent behaviors find evidence for two opposite trends: Sometimes a first behavior increases the likelihood of engaging in additional behaviors that contribute to the same goal (positive behavioral spillover), and at other times a first behavior decreases this likelihood (negative spillover). A factor that may explain both patterns is attitude strength. A stronger (more favorable) attitude toward an issue may make the connections between related behaviors more salient and increase the motivation to work toward the underlying goal. We predicted that people with a stronger (more favorable) attitude are more likely to engage in subsequent behaviors that address an issue they care about. Two experiments tested the prediction in the contexts of pro-environmental and health behavior. Study 1 (N = 378) provided some support for the predicted moderating role of attitude toward the environment when participants recalled either an environmentally friendly or unfriendly action: A strong attitude increased the likelihood, whereas a weak attitude decreased the likelihood of carrying out successive goal-conducive behaviors. When compared to a neutral control condition in Study 2 (N = 929), participants with a weak environmental attitude supported pro-environmental petitions less strongly after an environmentally harmful action. Support for such petitions did not waver, however, among participants with a strong environmental attitude: They consistently acted environmentally friendly. Contrary to the hypothesis, in neither study did strength of attitude toward personal health moderate the effect of an initial behavior in the expected direction. In sum, the two studies provided only limited evidence for behavioral spillover: Participants mostly acted in accordance with their attitude but were hardly affected by recalling previous actions. When behavioral spillover did occur, however, a strong environmental attitude tended to increase the likelihood of acting in an environmentally friendly way, whereas the behavior of those with a weak attitude was less predictable. This research contributes to a more nuanced theoretical understanding of the role of attitude in spillover, but provides only limited evidence for its role as a moderator.

Remembering and Communicating Climate Change Narratives - The Influence of World Views on Selective Recollection.

We examine how people remember stories about climate change and how they communicate these stories to others. Drawing on theories of reconstructive memory and cultural theory, we assume that recollection is systematically affected by an individual’s world view as well as by the world view of the target audience. In an experimental study with a Norwegian representative sample (N = 266), participants read a story about three politicians, in which each protagonist was described as holding a specific world view and as trying to tackle climate change with a corresponding strategy (individualistic/free market oriented, hierarchical/technology-oriented, or egalitarian/sustainability-oriented). After 1 day and then after 1 week, participants were asked to retell the story as if to somebody who was characterized as being either an individualist, a hierarchist, or an egalitarian; in addition, a neutral recall control condition without a specified audience was included. Participants’ own world view was assessed and they were classified as endorsing individualism, or hierarchism, or egalitarianism. We hypothesized that retellings would be selectively reconstructed according to the world view of the participant, as well as tuned to the audience’s world view. We assessed the cognitive structure of the recollected story, and, using methods from computational text analysis, we computed similarities among retellings and the original narrative, and among retellings and world views. Results suggest that (i) retellings become less accurate over time, (ii) retelling to an audience with an explicit world view leads to more strongly filtered retellings than recalling without a specified audience, but the filter operates in a non-specific manner with respect to world views, (iii) the cognitive structure of the recollected story shows small but systematic differences concerning the link between story problem and solution as a function of the participant’s and the audience’s world view. No interaction was found between the world view of the participant and that of the audience. Results emphasize the role of world views in communicating climate change, and might help to better understand phenomena such as polarization and echo chamber effects.