This work reviews retrofitting new waste energy, carbon and water intensive technologies into existing industrial facilities (including electricity generators) to increase net energy, carbon, and water use efficiencies. The three applications reviewed are microalgal ponds consuming flue gasses and providing thermal power station cooling services, thermally driven membrane distillation desalination, and hydrometallurgical solution mining processes to indirectly remove water contaminants, and additional power station cooling. The aim of this work is to explore the unique challenge of site-specificity of retrofitting any or all of the reviewed technologies within existing facilities for commercial operations. The theoretical basis behind higher aggregated efficiencies is essentially vertical integration of infrastructure, energy, and material flows, reducing total costs, net waste, and associated potential environmental contamination. Whilst solution mining and some thermal desalination technologies are not necessarily new in isolation, new technical developments enable these technologies to use waste heat and waste water by operating in parallel with industrial facilities, and effectively subsidise microalgae biofuel water pumping and dewatering. This research determines three fundamental developments are required to enable wide-scale industrial co-located vertical integration efficiencies: (1) fundamental engineering, (2) monitoring system innovation, and (3) technology/knowledge transfer.