The present study was designed to determine the acceptability of PIHCT on pregnant mothers attended ANC at Nekemte government health facilities. A cross-sectional study was conducted from May 1, to June 7, 2009. Modified standardized questionnaires and in-depth interviews were used. Total 422 participants were involved, of these 274 from Nekemte hospital and 148 from Nekemte health center with 100% response rate. The mean age of the participants were 24.24 with SD of 5.02 and their age ranges were 16 to 40. The overall acceptability rate was 370(87.7%). Almost all the respondents 412(97.6%) were knowledgeable to the three cardinal ways of prevention of HIV/AIDS (i.e. Abstinence, avoiding multiple sexual partners and sharing sharps). But 151(35.8%) were knowledgeable to the three methods of HIV transmission from mother to child during pregnancy, child birth & breast feeding. Three hundred ten (73.9%) of the mothers perceived themselves not at risk of HIV/AIDS. Pre-test counseling was given for 337(79.9%) of the mothers (P=0.002). Health workers 260(61.6%) were the most common source of information. Media and religious leaders played a little role in dissemination of information. Acceptability to PIHCT in this study is remarkable. Improving participation of religious leaders and HCWs by giving continuous in-service and pre-service training, couple counseling and designing strategies on change of attitude and practice were recommended.
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