The risk of a severe course of new coronavirus infection(COVID-19) due to the development of acute respiratory distress syndrome is extremely high, which is especially true forpatients with comorbidities.The aimof the study is to demonstrate the peculiarities ofthe course and intensive care measures in new coronavirusinfection COVID-19 in children with comorbidities.Patients and methods:On the example of clinical cases,the characteristics of the course of a new coronavirus infection of COVID-19 in children with systemic lupus erythematosus and bronchopulmonary dysplasia are considered.Results:The main data from the history and clinical laboratory examination are reflected, which made it possible toidentify a cytokine storm in a timely manner, a high risk ofadverse course and begin timely specific pathogenetic therapy, including immunoglobulins for intravenous administration, hydroxychloroquine, ritonavir in combination withlopinavir, azithromycin and dexamethasone. Particular attention is paid to the need to limit infusion therapy, maintaina negative water balance and optimal blood oxygen capacity,ambiguity of opinions on the need for routine use of albuminand dexamethasone solutions in patients with COVID-19 hasbeen demonstrated.Conclusion:Children with comorbidities are characterized by a severe course of a new coronavirus infection COVID-19, which requires timely pathogenetic therapy takinginto account the individual characteristics of the patient.
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